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Drug Interactions between Acid Reducer Plus Antacid and Malarone

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

calcium carbonate proguanil

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Malarone (atovaquone / proguanil)

Using calcium carbonate together with proguanil can decrease the effects of proguanil. Calcium carbonate and proguanil should be taken at least 2 to 3 hours apart. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

magnesium hydroxide proguanil

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Malarone (atovaquone / proguanil)

Using magnesium hydroxide together with proguanil can decrease the effects of proguanil. Magnesium hydroxide and proguanil should be taken at least 2 to 3 hours apart. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

famotidine calcium carbonate

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Minor

famotidine magnesium hydroxide

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide) and Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

calcium carbonate food

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

atovaquone food

Applies to: Malarone (atovaquone / proguanil)

Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone at the same time each day with a meal or a milky drink. If you receive enteral nutrition (tube feeding), take atovaquone with your feeding. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking atovaquone with food.

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Minor

famotidine food

Applies to: Acid Reducer Plus Antacid (calcium carbonate / famotidine / magnesium hydroxide)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.