Drug Interactions between acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide and fentanyl / ropivacaine
This report displays the potential drug interactions for the following 2 drugs:
- acetaminophen/aluminum hydroxide/aspirin/caffeine/magnesium hydroxide
- fentanyl/ropivacaine
Interactions between your drugs
aspirin aluminum hydroxide
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide and acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Using aluminum hydroxide together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin magnesium hydroxide
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide and acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Using magnesium hydroxide together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
acetaminophen ROPivacaine
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide and fentanyl / ropivacaine
Using acetaminophen together with ROPivacaine may cause methemoglobinemia, a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood. Individuals may be more susceptible to developing methemoglobinemia during treatment with these medications if they are very young (especially neonates and infants) or have diseases of the heart or lungs, certain genetic predispositions, or glucose-6-phosphate dehydrogenase deficiency. Medical supervision may be necessary when medications that can cause methemoglobinemia are used together. Signs and symptoms of methemoglobinemia may occur immediately or hours after treatment. Patients or their caregivers should seek immediate medical attention if they develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin caffeine
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide and acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Information for this minor interaction is available on the professional version.
caffeine ROPivacaine
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide and fentanyl / ropivacaine
Information for this minor interaction is available on the professional version.
Drug and food interactions
fentaNYL food
Applies to: fentanyl / ropivacaine
Do not use alcohol or medications that contain alcohol while you are receiving treatment with fentaNYL. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. You should also avoid consuming grapefruit and grapefruit juice, as this may increase the blood levels and effects of fentanyl. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Do not use more than the recommended dose of fentaNYL, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
aluminum hydroxide food
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Citrate, or citric acid, can increase the absorption of aluminum hydroxide. This may lead to elevated blood levels of aluminum, particularly in individuals with reduced kidney function, since aluminum is primarily eliminated by the kidneys. Excess aluminum may deposit and cause problems in various tissues including bone, brain, heart, liver, muscles, and spleen. Over time, weak bones, bone pain, fractures, skeletal deformity, brain disorders, and anemia may develop. Talk to your doctor before using aluminum hydroxide if you have kidney impairment or are on hemodialysis. You should avoid or limit the consumption of citrate-containing foods and beverages (e.G., soft drinks, citrus fruits, fruit juices) during treatment with aluminum hydroxide. Be aware that some effervescent and dispersible drug formulations may also contain citrate and should be restricted as well. Even if you do not have kidney problems, it may be best to separate the dosing of aluminum hydroxide and citrate-containing products by 2 to 3 hours. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
When aluminum hydroxide is taken during enteral nutrition therapy (tube feeding), the tube may get clogged. Therefore, aluminum hydroxide should not be mixed with or given after high-protein tube feedings. The dose should be separated from the feeding by as much as possible, and the tube should be thoroughly flushed before administration of the dose.
acetaminophen food
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin food
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
caffeine food
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Information for this minor interaction is available on the professional version.
aspirin food
Applies to: acetaminophen / aluminum hydroxide / aspirin / caffeine / magnesium hydroxide
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.