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Trifunctional monoclonal antibodies

What are Trifunctional monoclonal antibodies?

Standard monoclonal antibodies have a two matching antigen binding sites and one Fc section that binds to Fc receptor on the antigen-presenting cell .

Trifunctional monoclonal antibodies are made by combining the fragments of two different standard monoclonal antibodies which results in a monoclonal antibody with two different types of antigen binding sites. This makes the antibody bispecific and able to bind to two different sites, for example both a tumour cell and a T cell while still attaching to the Fc receptor of the antigen-present cell.

This makes the trifunctional monoclonal antibody more potent than standard monoclonal antibodies.

There are no drugs in this category. Some medications may have been reclassified. See antineoplastics.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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