Ketolides
What are Ketolides
Ketolides are a new generation of macrolide antibiotics designed to overcome issues with bacterial resistance to macrolides. They are semi-synthetic antibiotics derived from erythromycin (macrolide antibiotic) and the changes give ketolides a broader spectrum of activity.
Ketolides bind to the bacterial 50S ribosomal subunit and inhibit RNA-dependent protein synthesis. They are bacteriostatic at low concentrations and bactericidal at high concentration, so basically exhibit concentration dependent killing.
Ketolides have good antibacterial activity against Gram-positive bacteria such as those that cause respiratory tract infections.
List of Ketolides:
| Drug Name |
Reviews | Ratings |
|
|---|---|---|---|
| Ketek (Pro, More...) generic name: telithromycin |
0 reviews | 0.0 | |
| Ketek Pak (More...) generic name: telithromycin |
0 reviews | 0.0 | |
See also...
Medical conditions associated with ketolides: