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What are Ketolides?

Ketolides are a new generation of macrolide antibiotics designed to overcome issues with bacterial resistance to macrolides. They are semi-synthetic antibiotics derived from erythromycin (macrolide antibiotic) and the changes give ketolides a broader spectrum of activity.

Ketolides bind to the bacterial 50S ribosomal subunit and inhibit RNA-dependent protein synthesis. They are bacteriostatic at low concentrations and bactericidal at high concentration, so basically exhibit concentration dependent killing.

Ketolides have good antibacterial activity against Gram-positive bacteria such as those that cause respiratory tract infections.

List of Ketolides

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Ketek Pak
Generic name: telithromycin
No reviews
Generic name: telithromycin
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions treated or associated with ketolides:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.