Integrase strand transfer inhibitor

Integrase strand transfer inhibitors block the action of integrase, a viral enzyme of the human immunodeficiency virus Type 1 (HIV-1), that is involved in integrating viral DNA into the host chromosome. Integration of the viral DNA into the host DNA is necessary for viral replication. Integrase strand transfer inhibitors is not a cure for HIV or AIDS but is used to prevent human immunodeficiency virus from multiplying in the host.