There is no reason to withhold breastfeeding after tuberculosis skin testing or to avoid skin testing in nursing mothers.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
There is some evidence that breastfed infants can acquire immune responsiveness to tuberculin via breastmilk.[1-3] However, other investigators have found no evidence of breastmilk transfer of immunity.[4]
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
1.
MartÃnez-Cairo Cueto, S, Alasio-Chavez C, Davila Velasquez, JR. In vitro transfer of immunity against PPD with dialyzable extract of leukocytes from human colostrum. Rev Alerg 1992;39:126-32. [PubMed: 1492196]
2.
Schlesinger JJ, Covelli HD. Evidence for transmission of lymphocyte responses to tuberculin by breast-feeding. Lancet 1977;310:529-32. [PubMed: 95733]
3.
Masters PL. Maternal transmission of skin sensitivity to tuberculin. Lancet 1982;2:276-7. [PubMed: 6124704]
4.
Keller MA, Rodgriguez AL, Alvarez S, et al. Transfer of tuberculin immunity from mother to infant. Pediatr Res 1987;22:277-81. [PubMed: 3658548]
Substance Identification
Substance Name
Tuberculin
CAS Registry Number
92129-86-7
Drug Class
Breast Feeding
Lactation
Milk, Human
Antigens
Purified Protein Derivative
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