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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Neosporin, Cortisporin Otic, Polytrim, Maxitrol, Triple Antibiotic, Antibiotic Plus Pain Relief, Polysporin First Aid Antibiotic Ointment, Polysporin Ophthalmic, Terramycin with Polymyxin B Sulfate, Cortisporin Ophthalmic Suspension, Show all 90 »Neosporin Ophthalmic, Neosporin Ophthalmic Ointment, Neo-Poly-Dex, Cortisporin Ointment, Antibiotic Ear, Neosporin + Pain Relief Cream, Polytracin Ophthalmic, Dexacine, Cortisporin Cream, Mycitracin Plus Pain Reliever, Statrol, Methadex, NPD Ophthalmic Ointment, Triple Antibiotic HC Ophthalmic Ointment, Dexacidin, Neo-Polycin, Septa, Mycitracin Triple Antibiotic, Neocin-PG, Neoptic, Neo/PolyB/HC, AK-Spore, Ocu-Spore-G, Neocidin Ophthalmic Solution, Cortomycin Suspension, Otimar, Oti-Sone, Cort-Biotic, Cortatrigen, Otobiotic, Neosporin G U Irrigant, Terak, Poly Pred, Antibiotic with Pramoxine, UAD Otic, Otocort Sterile Suspension, Masporin Otic, Drotic, AK-Spore HC Otic Suspension, Otocort Sterile Solution, Cortatrigen Modified, Pediotic, Poly-Dex, Cortomycin, Ophthocort, AK-Spore Ointment, Triple Antibiotic Ophthalmic Ointment, Neocidin, Ocutricin, Neocin, Medi-Quik, Ocu-Spore-B, Sx1 Medicated Post-Operative System, First Aid Triple Antibiotic with Pain Reliever, Neo-Poly-Bac, Cortomycin Eye Ointment, Neo-Polycin HC, Ocu-Cort, Neotricin HC, ProCoMycin, Cortisporin Ophthalmic Ointment, Tribiotic Plus, NEO TO GO!, Betadine Antibiotic, Polytracin, Duospore, Betadine Plus Antibiotic and Pain Reliever, Campho-Phenique Maximum Strength, AK-Trol, Dexasporin, Polycin-B, AK-Poly-Bac, Neosporin + Pain, Itch, Scar, Neosporin + Pain Relief Ointment, Neosporin + Pain Relief Neo To Go! First Aid Antibiotic, Lanabiotic, Spectrocin Plus, Polycin, Triple Antibiotic Plus, Ocu-Trol

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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