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Polymyxin B use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on Jun 20, 2024.

Drugs containing Polymyxin B: Neosporin, Polytrim, Cortisporin Otic, Maxitrol, Triple Antibiotic, Polysporin First Aid Antibiotic Ointment, Antibiotic Plus Pain Relief, Polysporin Ophthalmic, Terramycin with Polymyxin B Sulfate, Betadine Antibiotic, Show all 94 »Neo-Poly-Dex, Pediotic, Cortisporin Ointment, Polytracin Ophthalmic, Neosporin Ophthalmic, Septa, Mycitracin Triple Antibiotic, Polycin, Cortisporin Ophthalmic Suspension, Antibiotic Ear, Cortisporin Cream, Neotricin HC, Dexacidin, Otocort Sterile Solution, Cortomycin Eye Ointment, First Aid Triple Antibiotic with Pain Reliever, Ocutricin, Neosporin Ophthalmic Ointment, Dexacine, Cortomycin, Casporyn HC, Drotic, Oti-Sone, Campho-Phenique Maximum Strength, Neo-Polycin HC, Neo-Poly-Bac, Triple Antibiotic HC Ophthalmic Ointment, Ocu-Cort, Cortisporin Ophthalmic Ointment, ProCoMycin, Sx1 Medicated Post-Operative System, Neo-Polycin, Neocidin, Triple Antibiotic Ophthalmic Ointment, AK-Spore Ointment, Neocin, Ocu-Spore-B, Medi-Quik, Tribiotic Plus, Curad Triple Antibiotic, NEO TO GO!, Neosporin + Pain Relief Neo To Go! First Aid Antibiotic, Neosporin + Pain Relief Ointment, Neosporin + Pain, Itch, Scar, Mycitracin Plus Pain Reliever, Lanabiotic, Spectrocin Plus, Triple Antibiotic Plus, Neosporin + Burn Relief, AK-Poly-Bac, Polycin-B, Simply Neosporin, Duospore, Polytracin, Betadine Plus Antibiotic and Pain Reliever, Ophthocort, NPD Ophthalmic Ointment, Dexasporin, Methadex, AK-Trol, Ocu-Trol, Poly-Dex, Neocin-PG, Neoptic, Ocu-Spore-G, Neocidin Ophthalmic Solution, AK-Spore, Cortomycin Suspension, Neo/PolyB/HC, AK-Spore HC Otic Suspension, Masporin Otic, Cortatrigen Modified, Otimar, Otocort Sterile Suspension, UAD Otic, Cortatrigen, Cort-Biotic, Otobiotic, Statrol, Neosporin G U Irrigant, Neosporin + Pain Relief Cream, Antibiotic with Pramoxine, Poly Pred, Terak

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1.
Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin 2006;24:167-97. [PubMed: 16677965]
2.
Noti A, Grob K, Biedermann M, et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol 2003;38:317-25. [PubMed: 14623482]

Substance Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Breast Feeding

Lactation

Milk, Human

Anti-Infective Agents

Antibacterial Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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