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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Cortisporin Otic, Neosporin, Maxitrol, Polytrim, Polysporin, Triple Antibiotic, Antibiotic Plus Pain Relief, Cortisporin Ophthalmic Suspension, Neo-Poly-Dex, Antibiotic Ear, Show all 90 »Terramycin with Polymyxin B Sulfate, Polysporin Ointment, Neosporin Ophthalmic, Dexacidin, Neosporin Ophthalmic Ointment, Polytracin Ophthalmic, Polysporin Ophthalmic, Cortisporin Ointment, Lanabiotic, Ocutricin, Neocidin Ophthalmic Solution, Neosporin + Pain Relief Neo to Go!, ProCoMycin, Septa, Methadex, Cortisporin Cream, Cortisporin Ophthalmic Ointment, AK-Poly-Bac, Betadine Antibiotic, Otobiotic, Neo-Polycin HC, Neocin, Triple Antibiotic HC Ophthalmic Ointment, Poly Pred, Neosporin G U Irrigant, Dexacine, Otocort Sterile Solution, Masporin Otic, AK-Spore HC Otic Suspension, Neo/PolyB/HC, Cortomycin Suspension, Neotricin HC, Cortomycin, Cortatrigen Modified, Drotic, Cort-Biotic, Neosporin Plus Maximum Strength, Neosporin Plus, Antibiotic with Pramoxine, Neo-Poly-Bac, Cortomycin Eye Ointment, Terak, Ocu-Cort, Statrol, Otocort Sterile Suspension, Pediotic, UAD Otic, Cortatrigen, Oti-Sone, Otimar, AK-Trol, Mycitracin Plus Pain Reliever, NEO TO GO!, Spectrocin Plus, Triple Antibiotic Plus, Polycin, Neosporin Plus Maximum Strength Ointment, Tribiotic Plus, Mycitracin Triple Antibiotic, Triple Antibiotic Ophthalmic Ointment, Neocidin, AK-Spore Ointment, Ocu-Spore-B, Medi-Quik, Polycin-B, Duospore, Ocu-Trol, Neo-Polycin, Poly-Dex, Neocin-PG, Ocu-Spore-G, Neoptic, Dexasporin, NPD Ophthalmic Ointment, Betadine Plus Antibiotic and Pain Reliever, Polytracin, Ophthocort, Campho-Phenique Maximum Strength, First Aid Triple Antibiotic with Pain Reliever, AK-Spore

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

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