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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Cortisporin Otic, Polytrim, Maxitrol, Neosporin, Triple Antibiotic, Polysporin First Aid Antibiotic Ointment, Cortisporin Cream, Polysporin Ophthalmic, Terramycin with Polymyxin B Sulfate, Antibiotic Plus Pain Relief, Show all 90 »Cortisporin Ophthalmic Suspension, Neosporin Ophthalmic, Cortisporin Ointment, Neo-Poly-Dex, Triple Antibiotic Ophthalmic Ointment, Neo-Polycin, Polycin, Otobiotic, Antibiotic with Pramoxine, Polytracin Ophthalmic, Septa, Ocutricin, Neosporin + Pain Relief Ointment, Otocort Sterile Suspension, Otimar, Mycitracin Plus Pain Reliever, Triple Antibiotic HC Ophthalmic Ointment, Neosporin Ophthalmic Ointment, Dexasporin, Methadex, Dexacine, Antibiotic Ear, Cortomycin Suspension, Neocidin Ophthalmic Solution, Neo/PolyB/HC, Neo-Polycin HC, Ocu-Spore-G, AK-Spore, Pediotic, Cortomycin, AK-Spore HC Otic Suspension, Drotic, Masporin Otic, Otocort Sterile Solution, Cortatrigen Modified, UAD Otic, Cortatrigen, Cort-Biotic, Oti-Sone, Statrol, Neosporin G U Irrigant, Neosporin + Pain Relief Cream, Poly Pred, Terak, Neoptic, Cortomycin Eye Ointment, Neocin-PG, Neosporin + Pain Relief Neo To Go! First Aid Antibiotic, Ocu-Cort, Neotricin HC, Cortisporin Ophthalmic Ointment, ProCoMycin, First Aid Triple Antibiotic with Pain Reliever, Sx1 Medicated Post-Operative System, Neocidin, AK-Spore Ointment, Neocin, Ocu-Spore-B, Medi-Quik, Mycitracin Triple Antibiotic, Tribiotic Plus, NEO TO GO!, Neosporin + Pain, Itch, Scar, Poly-Dex, Betadine Plus Antibiotic and Pain Reliever, Ocu-Trol, AK-Trol, Dexacidin, NPD Ophthalmic Ointment, Neo-Poly-Bac, Ophthocort, Betadine Antibiotic, Lanabiotic, Polytracin, Duospore, Polycin-B, AK-Poly-Bac, Triple Antibiotic Plus, Spectrocin Plus, Campho-Phenique Maximum Strength

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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