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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Cortisporin Otic, Maxitrol, Neosporin, Polytrim, Polysporin, Triple Antibiotic, Cortisporin Ophthalmic Suspension, Antibiotic Plus Pain Relief, Neo-Poly-Dex, Antibiotic Ear, Show all 90 »Terramycin with Polymyxin B Sulfate, Neosporin Ophthalmic Ointment, Neosporin Ophthalmic, Cortisporin Ointment, Polytracin Ophthalmic, Polysporin Ophthalmic, Pediotic, Lanabiotic, Ocutricin, Neocin, Poly Pred, Neocidin Ophthalmic Solution, Polysporin Ointment, Dexacidin, Poly-Dex, AK-Poly-Bac, Polycin, Cortisporin Ophthalmic Ointment, Neosporin + Pain Relief Neo to Go!, Septa, Neosporin G U Irrigant, Otobiotic, Triple Antibiotic Plus, AK-Spore, Drotic, Triple Antibiotic HC Ophthalmic Ointment, AK-Spore HC Otic Suspension, Cortomycin Suspension, Neo/PolyB/HC, Cortomycin, Masporin Otic, Cortomycin Eye Ointment, Cortatrigen, Neo-Poly-Bac, Statrol, Neosporin Plus, Terak, Antibiotic with Pramoxine, Neosporin Plus Maximum Strength, Cortisporin Cream, Oti-Sone, Otimar, Cortatrigen Modified, Otocort Sterile Suspension, UAD Otic, Cort-Biotic, Ocu-Spore-G, Otocort Sterile Solution, Dexasporin, Tribiotic Plus, Mycitracin Triple Antibiotic, NEO TO GO!, Mycitracin Plus Pain Reliever, Neosporin Plus Maximum Strength Ointment, Spectrocin Plus, Medi-Quik, Neotricin HC, Neo-Polycin, First Aid Triple Antibiotic with Pain Reliever, Neocidin, Triple Antibiotic Ophthalmic Ointment, Ocu-Spore-B, AK-Spore Ointment, Polycin-B, Ocu-Cort, Methadex, ProCoMycin, AK-Trol, Dexacine, Neocin-PG, Ocu-Trol, NPD Ophthalmic Ointment, Neo-Polycin HC, Polytracin, Duospore, Betadine Antibiotic, Betadine Plus Antibiotic and Pain Reliever, Campho-Phenique Maximum Strength, Ophthocort, Neoptic

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

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