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Polymyxin B use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on Sep 5, 2024.

Drugs containing Polymyxin B: Neosporin, Polytrim, Cortisporin Otic, Maxitrol, Polysporin First Aid Antibiotic Ointment, Triple Antibiotic, Pediotic, Antibiotic Plus Pain Relief, Terramycin with Polymyxin B Sulfate, Polycin, Show all 94 »Neosporin Ophthalmic, Cortisporin Ointment, Polysporin Ophthalmic, Neo-Poly-Dex, Antibiotic Ear, Polytracin Ophthalmic, Cortisporin Ophthalmic Suspension, Ocutricin, Casporyn HC, Drotic, Cortisporin Cream, Neo-Polycin, Septa, Tribiotic Plus, Betadine Antibiotic, NPD Ophthalmic Ointment, Dexacidin, Methadex, Poly-Dex, Campho-Phenique Maximum Strength, Neo-Polycin HC, Cortomycin Eye Ointment, Neo-Poly-Bac, Triple Antibiotic HC Ophthalmic Ointment, Ocu-Cort, Neotricin HC, Cortisporin Ophthalmic Ointment, ProCoMycin, First Aid Triple Antibiotic with Pain Reliever, Sx1 Medicated Post-Operative System, Neocidin, Triple Antibiotic Ophthalmic Ointment, AK-Spore Ointment, Neocin, Neosporin Ophthalmic Ointment, Ocu-Spore-B, Medi-Quik, Mycitracin Triple Antibiotic, Curad Triple Antibiotic, NEO TO GO!, Neosporin + Pain Relief Neo To Go! First Aid Antibiotic, Neosporin + Pain Relief Ointment, Neosporin + Pain, Itch, Scar, Mycitracin Plus Pain Reliever, Lanabiotic, Spectrocin Plus, Triple Antibiotic Plus, Neosporin + Burn Relief, AK-Poly-Bac, Polycin-B, Simply Neosporin, Duospore, Polytracin, Betadine Plus Antibiotic and Pain Reliever, Ophthocort, Dexasporin, AK-Trol, Dexacine, Ocu-Trol, Neocin-PG, Neoptic, Ocu-Spore-G, Neocidin Ophthalmic Solution, AK-Spore, Cortomycin Suspension, Neo/PolyB/HC, Cortomycin, AK-Spore HC Otic Suspension, Masporin Otic, Otocort Sterile Solution, Cortatrigen Modified, Otimar, Otocort Sterile Suspension, UAD Otic, Cortatrigen, Cort-Biotic, Oti-Sone, Otobiotic, Statrol, Neosporin G U Irrigant, Neosporin + Pain Relief Cream, Antibiotic with Pramoxine, Poly Pred, Terak

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

Does Polymyxin b ophthalmic interact with my other drugs?

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References

1.
Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin 2006;24:167-97. [PubMed: 16677965]
2.
Noti A, Grob K, Biedermann M, et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol 2003;38:317-25. [PubMed: 14623482]

Substance Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Breast Feeding

Lactation

Milk, Human

Anti-Infective Agents

Antibacterial Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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