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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Cortisporin Otic, Neosporin, Maxitrol, Polytrim, Triple Antibiotic, Polysporin, Neo-Poly-Dex, Cortisporin Ophthalmic Suspension, Antibiotic Plus Pain Relief, Terramycin with Polymyxin B Sulfate, Show all 90 »Polysporin Ointment, Septa, Neosporin + Pain Relief Neo to Go!, Cortisporin Ophthalmic Ointment, Antibiotic Ear, Dexacidin, Cortisporin Ointment, ProCoMycin, Polysporin Ophthalmic, Neosporin Ophthalmic Ointment, Triple Antibiotic HC Ophthalmic Ointment, Neosporin Ophthalmic, Cortisporin Cream, Lanabiotic, Ocutricin, Poly Pred, Otocort Sterile Solution, Betadine Antibiotic, Dexacine, Neo-Polycin HC, Methadex, Polytracin Ophthalmic, AK-Poly-Bac, Drotic, Neocin, Masporin Otic, Cortomycin Suspension, Cortomycin Eye Ointment, Neo/PolyB/HC, AK-Spore HC Otic Suspension, Cortatrigen Modified, Terak, Cortomycin, Neotricin HC, UAD Otic, Neosporin Plus Maximum Strength, Antibiotic with Pramoxine, Otobiotic, Statrol, Neosporin Plus, Neosporin G U Irrigant, Oti-Sone, Cort-Biotic, Otocort Sterile Suspension, Pediotic, Ocu-Cort, Cortatrigen, Neo-Poly-Bac, Otimar, Ocu-Trol, Spectrocin Plus, Mycitracin Plus Pain Reliever, Triple Antibiotic Plus, Neosporin Plus Maximum Strength Ointment, Polycin-B, Polycin, NEO TO GO!, Tribiotic Plus, Ocu-Spore-B, AK-Spore Ointment, Neocidin, Neo-Polycin, Mycitracin Triple Antibiotic, Medi-Quik, Duospore, Polytracin, Poly-Dex, Triple Antibiotic Ophthalmic Ointment, Neocin-PG, Neoptic, Neocidin Ophthalmic Solution, Ocu-Spore-G, AK-Trol, Dexasporin, Ophthocort, Betadine Plus Antibiotic and Pain Reliever, Campho-Phenique Maximum Strength, First Aid Triple Antibiotic with Pain Reliever, NPD Ophthalmic Ointment, AK-Spore

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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