Erdafitinib Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the clinical use of erdafitinib during breastfeeding. Because erdafitinib is 99.8% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 59 hours in adults and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during erdafitinib therapy and for 1 month after the final dose.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Erdafitinib
CAS Registry Number
1346242-81-6
Drug Class
Breast Feeding
Lactation
Antineoplastic Agents
Enzyme Inhibitors
Protein Kinase Inhibitors
Signal Transduction Inhibitors
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