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Dill use while Breastfeeding

Dill Levels and Effects while Breastfeeding

Summary of Use during Lactation

Dill (Anethum graveolens) seeds contain essential oil rich in carvone and limonene, in addition to phenolic and flavonoids. Dill is a purported galactogogue.[1][2][3][4] No scientifically valid clinical trials support this use, and one small, old study found no galactogogue effect of a primary dill component, d-carvone.[5] Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[6] Two studies found small, but measurable amounts of d-carvone in the milk of mothers given the chemical experimentally. Dill is "generally recognized as safe" (GRAS) as a food by the US Food and Drug Administration. It is generally well tolerated, but occasional allergic skin reactions have been reported, especially after contact with fresh dill. In two studies, nursing mothers were given d-carvone. No adverse effects were noted in the mothers or infants. Dietary supplements do not require extensive pre-marketing approval from the US Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information about dietary supplements is available elsewhere on the LactMed Web site.

Drug Levels

Maternal Levels. Eighteen lactating women were given 100 mg of d-carvone mixed with lactose and talc in a capsule on 3 test days. Milk samples were collected every 2 hours for 8 hours starting at the time of ingestion. Carvone was detected in milk at all collection times, with the average concentrations of 1.3 mcg/L at 0 hours, 7.2 mcg/L at 2 hours, 5.6 mcg/L at 4 hours, 4.3 mcg/L at 6 hours and 2.7 mcg/L at 8 hours after the dose. The average peak carvone concentration in milk was 10.5 mcg/L. Carvone metabolites were not detected in any milk samples.[7]

In another study, 20 mothers consumed 30 mg of d-carvone in 75 grams of hummus every third day for 28 days (10 exposures) at about 2 hours before a "usual" nursing time. Breastmilk samples were obtained 2 hours after ingestion on the first and last days of carvone intake. Carvone was detectable in the milk of 18 mothers. Average carvone concentrations in breastmilk were 2.5 mcg/L and 3.8 mcg/L on the first and last days of sampling, respectively. However, these values did not differ statistically, and the combined average carvone concentration was 3.2 mcg/L. A control group of 20 women who did not ingest d-carvone had no detectable carvone in their breastmilk.[5]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

A study compared 3 groups of women. One group of 20 nursing mothers consumed 30 mg of d-carvone in 75 grams of hummus every third day for 28 days (10 exposures) at about 2 hours before a "usual" nursing time. A second group of 20 nursing mothers followed the same regimen, but their hummus contained no d-carvone. A third group of 8 mothers received the d-carvone flavored hummus, but were exclusively formula feeding their infants. After this 28-day period, both groups of breast-fed infants showed greater acceptance of d-carvone-flavored mashed potatoes than the formula-fed infants who preferred the unflavored potatoes. The authors interpreted these results to mean that breastfed infants are more receptive to a wide array of flavors than formula-fed infants.[5]

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1. Yarnell E. Botanical medicine in pregnancy and lactation. Altern Complement Ther. 1997;3 (April):93-100.

2. Kopec K. Herbal medications and breastfeeding. J Hum Lact. 1999;15:157-61. PMID: 10578793

3. Low Dog T. The use of botanicals during pregnancy and lactation. Altern Ther Health Med. 2009;15:54-8. PMID: 19161049

4. Alachkar A, Jaddouh A, Elsheikh MS et al. Traditional medicine in Syria: folk medicine in Aleppo governorate. Nat Prod Commun. 2011;6:79-84. PMID: 21366051

5. Hausner H, Nicklaus S, Issanchou S et al. Breastfeeding facilitates acceptance of a novel dietary flavour compound. Clin Nutr. 2010;29:141-8. PMID: 19962799

6. The Academy of Breastfeeding Medicine Protocol Committee. ABM clinical protocol #9: use of galactogogues in initiating or augmenting the rate of maternal milk secretion (First revision January 2011). Breastfeed Med. 2011;6:41-9. PMID: 21332371

7. Hausner H, Bredie WL, Molgaard C et al. Differential transfer of dietary flavour compounds into human breast milk. Physiol Behav. 2008;95:118-24. PMID: 18571209

Dill Identification

Substance Name

Dill

Scientific Name

Anethum graveolens

CAS Registry Number

8006-75-5

Drug Class

Complementary Therapies

Phytotherapy

Plants, Medicinal

Administrative Information

LactMed Record Number

959

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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