Botulin B use while Breastfeeding
Botulin B Levels and Effects while Breastfeeding
Summary of Use during Lactation
No data exist on the medical use of botulin B (botulinum toxin) during breastfeeding. However, one infant was safely breastfed during maternal botulism and no botulinum toxin was detectable in the mother's milk or infant. Since the doses used medically are far lower than those that cause botulism, amounts ingested by the infant, if any, are expected to be small and not cause any adverse effects in breastfed infants. No special precautions are required.
Maternal Levels. Published information on the medical use of botulin B during breastfeeding was not found as of the revision date.
Type A botulinum toxin was detected in the woman's blood and stools. No botulinum toxin was detected in the infant's blood or stool on the day the mother was admitted to the hospital and no botulism organisms were detected in the infant's stools. The mother was given 2 vials of trivalent botulism antitoxin, 1 intravenously and 1 intramuscularly. A milk sample obtained 4 hours after administration of the antitoxin had no detectable botulinum toxin nor botulism organisms.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Published information on the medical use of botulin B during breastfeeding was not found as of the revision date.
A woman developed botulism after ingesting fermented salmon eggs while breastfeeding her 8-month-old infant (extent not stated). The infant developed no signs or symptoms of botulism even though she continued to nurse throughout the mother's hospitalization.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
1. Lee KC, Korgavkar K, Dufresne RGJ et al. Safety of cosmetic dermatologic procedures during pregnancy. Dermatol Surg. 2013;39:1573-86. PMID: 24164677
2. Middaugh J. Botulism and breast milk. N Engl J Med. 1978;298:343. PMID: 622098
Botulin B Identification
CAS Registry Number
LactMed Record Number
Last Revision Date
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.