Benzalkonium Chloride use while Breastfeeding
Drugs containing Benzalkonium Chloride: Merthiolate, Tanac, First Aid Antiseptic, Mercuroclear, Dr Scholl's Cracked Heel Relief, Neosporin + Pain Relief Neo To Go! First Aid Antiseptic, Herpetrol, A + D Cracked Skin Relief, Cold Sore Treatment, CureChrome, Show all 15 »Neosporin Wound Cleanser, HandClens 2 in 1, Zephiran Chloride, Benza, Pedi-Pro (Benzalkonium)
Benzalkonium Chloride Levels and Effects while Breastfeeding
Summary of Use during Lactation
Topical maternal application of benzalkonium chloride or benzethonium chloride or their presence as a preservative in pharmaceuticals would not be expected to cause any adverse effects in breastfed infants.
Johnson W Jr. Final report on the safety assessment of benzalkonium chloride. J Am Coll Toxicol. 1989;8:589-625.
Effects in Breastfed Infants
A study in Japan randomized 80 consecutive term patients into 4 groups who received either povidone-iodine or benzethonium chloride as a skin disinfectant before delivery and one of these for postpartum vaginal lacerations. Prepartum doses were about 7 mL and postpartum doses were about 0.5 mL of solution. Infant thyrotropin levels were elevated in the infants whose mothers received topical povidone-iodine pre- and postpartum compared to infants whose mothers received benzethonium chloride.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
1. Johnson W Jr. Final report on the safety assessment of benzalkonium chloride. J Am Coll Toxicol. 1989;8:589-625.
2. Koga Y, Sano H, Kikukawa Y et al. Affect on neonatal thyroid function of povidone-iodine used on mothers during perinatal period. J Obstet Gynaecol. 1995;21:581-5. PMID: 8640469
Benzalkonium Chloride Identification
CAS Registry Number
Antiinfective Agents, Local
LactMed Record Number
Last Revision Date
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Drug class: antiseptic and germicides
Other brands: CureChrome