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Intense Chemo Offers Little Benefit for Early Breast Cancer: Study

Posted 9 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – A more intense type of chemotherapy offers little benefit over standard chemotherapy for women with high-risk early breast cancer, European researchers report. Known as tailored dose-dense chemotherapy, the treatments are given over a shorter period of time without increasing the overall dose. It has been suggested as a way to improve the effectiveness of the treatment for early breast cancer. However, the European study did not find a difference in recurrence-free survival or overall survival after five years of follow-up. The investigators did find that the dose-dense group had better event-free survival, defined as the time to any breast cancer relapse, cancer in the opposite breast, other malignant growths or death from any cause. Despite the results, a U.S. breast cancer expert said there is still a role for the approach in certain women. Researchers from ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Evista, Zoladex, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Breast Cancer - Adjuvant, Casodex

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Colorectal Cancer, Isotretinoin, Rituxan, Claravis

Hormone Therapy Safely Helps Preserve Fertility for Breast Cancer Patients: Study

Posted 22 Dec 2015 by Drugs.com

TUESDAY, Dec. 22 2015 – Chemotherapy can affect a young breast cancer patient's fertility, sending her into premature menopause, so in many cases doctors provide patients with hormonal therapy during chemo to prevent this side effect. Now, new research suggests that the approach does help these patients without lowering their odds of surviving the cancer. One expert noted that the issue is a tough one for many young breast cancer patients. "The most reliable way in 2015 to preserve a patient's fertility is through egg harvesting prior to chemotherapy and in vitro fertilization," explained Dr. Charles Shapiro, director of translational breast cancer research at Mount Sinai Medical Center in New York City. "However, as this procedure is typically not covered by insurance, it is only an option for those of financial means," he said. "So, those who cannot afford the procedure can choose to ... Read more

Related support groups: Hot Flashes, Breast Cancer, Menopausal Disorders, Female Infertility, Postmenopausal Symptoms, Ovulation Induction, Perimenopausal Symptoms, Breast Cancer - Adjuvant, Trelstar, Primary Ovarian Failure, Follicle Stimulation, Trelstar LA, Trelstar Depot, Triptorelin

Early Chemo Less Likely to Help Black Breast Cancer Patients: Study

Posted 12 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Early chemotherapy is less likely to benefit black women with breast cancer than those in other racial and ethnic groups, a new study finds. Advanced breast cancer is more common among black, Hispanic and Asian women than it is in white women. As a result, black women often receive chemotherapy before surgery in an effort to improve their outcomes, the Yale University Cancer Center researchers said. But their study of 27,300 women with stage 1 to 3 breast cancer showed that early (neoadjuvant) chemotherapy was less effective in black patients than in other women. "Even when we controlled for the fact that minority women often present with more advanced-stage, higher-grade tumors, and more aggressive types of breast cancer overall, our team was surprised to find that black women did not respond as well to neoadjuvant chemotherapy compared to other racial groups," ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Breast Cancer - Adjuvant, Casodex

Two Drugs Equal in Preventing Early Breast Cancer's Return: Study

Posted 11 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Postmenopausal women who have an early, noninvasive form of breast cancer had similar recurrence rates of disease whether they took the drug tamoxifen or the aromatase inhibitor anastrozole after surgery, new research shows. However, the side effects of the two medications differed greatly, said study author Jack Cuzick, director of the Wolfson Institute of Preventive Medicine at Queen Mary University of London, England. His team looked at nearly 3,000 women, all past menopause, who had hormone-receptor positive ductal carcinoma in situ (DCIS) breast cancer and underwent surgery to excise it. With DCIS, the cells that line the milk ducts have changed but not spread into the surrounding breast tissue. Half the women were randomly assigned to take 1 milligram (mg) a day of anastrozole (Arimidex), while the other half took 20 mg a day of tamoxifen (Nolvadex). Each ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Breast Cancer - Adjuvant, Casodex

Timing May Be Key to Success of Surgery, Chemo for Early Breast Cancer

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – The sooner early stage breast cancer patients have surgery following their diagnosis, and chemotherapy after their surgery, the better their chances of survival, two new studies find. In one study, researchers at Fox Chase Cancer Center in Philadelphia analyzed data from more than 94,500 American women aged 66 and older. All were diagnosed with breast cancer between 1992 and 2009. The team, led by Dr. Richard Bleicher, found a 9 percent increased risk of death from all causes for each 30-day delay in the time from diagnosis to surgery. The link between time to surgery and risk of death from all causes was only statistically significant for patients with earlier stages of cancer, the researchers noted. In the study, delays seemed to affect prognosis for patients with stage 1 and stage 2 cancers, but not for those with stage 3 cancers. The findings were similar ... Read more

Related support groups: Surgery, Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Breast Cancer - Adjuvant

Depression May Be Tied to Lower Breast Cancer Survival

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – Breast cancer patients with depression may have a much higher risk of death than those without the mental illness, a new study suggests. "Low mood and depression are understandable reactions to a breast cancer diagnosis. Clinicians generally know to look out for this, but these findings emphasize the need to ask patients with cancer about their mood and for women to know it's OK to ask for help," Elizabeth Davies, of the division of health and social care research and cancer studies at King's College London, said in a school news release. "It is important women feel they can talk about these feelings and do not feel guilty about difficulty coping or depression, which can be a natural response to cancer diagnosis," she added. Although this study found a link between depression and breast cancer survival, it's important to note that the research can't prove ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Effexor, Prozac, Provera, Celexa, Depo-Provera, Citalopram, Paxil, Major Depressive Disorder, Sertraline, Pristiq, Amitriptyline, Fluoxetine, Venlafaxine, Effexor XR, Breast Cancer, Mirtazapine

Lumpectomy Plus Radiation May Beat Mastectomy for Early Breast Cancer

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – Women with early stage breast cancer may survive longer if they opt for the less-extensive surgery called lumpectomy, followed by radiation, rather than a mastectomy, a new study suggests. "I think these results offer women important information to discuss with their doctors when making a treatment decision for early stage breast cancer," said lead researcher Sabine Seisling, of the Netherlands Comprehensive Cancer Organization, in Utrecht. Mastectomy removes the entire the breast, while lumpectomy involves removing only the tumor with some surrounding tissue. Some studies have suggested that women with early stage breast cancer have a better five-year survival rate after lumpectomy. The new study, which included 37,000 Dutch women, found that the advantage may also extend to the longer term. Of nearly 22,000 patients who underwent lumpectomy plus radiation, ... Read more

Related support groups: Surgery, Cancer, Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Femara, Lupron Depot, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Breast Cancer - Adjuvant, Casodex

Cooling Cap to Reduce Chemo-Linked Hair Loss OK'd

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – The Dignitana Cooling System cap has been approved by the U.S. Food and Drug Administration to help prevent hair loss in women undergoing chemotherapy for breast cancer. A computer-controlled system circulates cooled liquid to the cap during chemotherapy. This is designed to constrict blood vessels in the scalp, limiting the amount of chemotherapy drugs that reach the hair follicles, the agency said in a news release. In clinical testing, more than two-thirds of women who wore the cap reported losing less than half of their hair. And the likelihood of chemotherapy drugs missing an isolated cluster of breast cancer cells in the scalp because of the cap was "extremely rare," the FDA said. But since the cap doesn't work with all chemotherapy drugs, any woman interested in using the product should speak with her doctor, the FDA advised. The most common side ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Alopecia, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Breast Cancer - Adjuvant, Casodex

Drugs May Protect the Heart During Chemotherapy

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – Two kinds of medications can prevent heart damage in breast cancer patients as they undergo chemotherapy, a new study suggests. Chemotherapy improves survival among women with early-stage breast cancer, but can dramatically increase their risk of heart failure, the researchers explained. This five-year study of 100 early-stage breast cancer patients in Canada found that two kinds of heart medicines – beta blockers and ACE inhibitors – seem to protect the heart during chemotherapy. "We think this is practice-changing. This will improve the safety of the cancer treatment that we provide," study co-investigator Edith Pituskin, an assistant professor in the Faculty of Nursing and Faculty of Medicine and Dentistry at the University of Alberta in Canada, said in a university news release. The heart medications not only protect the heart, but may also improve ... Read more

Related support groups: Lisinopril, Provera, Depo-Provera, Metoprolol, Atenolol, Breast Cancer, Propranolol, Heart Failure, Lupron, Congestive Heart Failure, Bystolic, Tamoxifen, Medroxyprogesterone, Carvedilol, Ramipril, Bisoprolol, Arimidex, Coreg, Lupron Depot, Femara

Researchers Focus on Risk Factors for Leukemia After Breast Cancer Treatment

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – Researchers say they're zeroing in on factors that may increase the risk of leukemia after breast cancer treatment. The findings are a step forward in determining ways to prevent this complication in breast cancer survivors. While the breast cancer treatments target malignant cells, they can also affect healthy cells and could increase the risk of leukemia later, the researchers said. The scientists looked at 88 breast cancer survivors with treatment-related leukemia and found that many had a personal and family history of cancer, suggesting a genetic susceptibility to cancer. Also, 20 percent of the women had an inherited gene mutation that increases the risk of breast cancer, according to the study published Dec. 7 in the journal Cancer. "The findings justify a long-term, follow-up study of women with and without inherited breast cancer gene mutations who are ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Leukemia, Femara, Lupron Depot, Breast Cancer, Metastatic, Anastrozole, Evista, Zoladex, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Casodex

Risk of More Aggressive Early Breast Cancers Rises With Age, Study Finds

Posted 27 Oct 2015 by Drugs.com

TUESDAY, Oct. 27, 2015 – While experts know the chances of finding a type of early stage breast cancer known as DCIS increase with age, a new study from Germany shows these cancers are more likely to be aggressive when discovered in older women. "DCIS detection rates increase with age, mostly due to a rise of DCIS high- and intermediate-grade [tumors]," said Dr. Stefanie Weigel, a researcher at University Hospital Muenster in Germany. These tumors, she said, are lesions that "carry a higher risk for transition to aggressive cancers than DCIS low-grade." DCIS, or ductal carcinoma in situ, is an early stage cancer that is potentially invasive. It is confined within the milk ducts and a common finding on mammography. Treating DCIS is controversial, because some cases may never progress and cause problems during a woman's lifetime. Weigel's team aimed to look at the link between age at ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Femara, Lupron Depot, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Casodex, Exemestane, Eligard, Lupron Depot 3.75 mg

Some Prostate Cancer Patients May Not Benefit From Hormone Therapy

Posted 22 Sep 2015 by Drugs.com

TUESDAY, Sept. 22, 2015 – Men with prostate cancer who also have had a heart attack may fare better with radiation therapy alone rather than with the standard treatment of radiation plus hormone therapy, a new analysis suggests. Over an average of 17 years of follow-up, men with high-risk prostate cancer who also had a heart condition lived longer after radiation treatment alone than similar men who had radiation and hormone therapy. Men who didn't have heart problems lived longer if they had both treatments, the researchers added. "There have been several trials looking at radiation with or without hormone therapy in high-risk prostate cancer which found a survival benefit from combined treatment," said lead researcher Dr. Anthony D'Amico, chief of radiation oncology at Brigham and Women's Hospital in Boston. However, whether hormone therapy causes an increase in death from heart ... Read more

Related support groups: Heart Attack, Testosterone, Lupron, Prostate Cancer, AndroGel, Testim, Lupron Depot, Axiron, Myocardial Infarction, Zoladex, Androderm, Lupron Depot 3.75 mg, Eligard, Depo-Testosterone, Fortesta, Testopel, Leuprolide, Lupron Depot-PED, Testopel Pellets, Methyltestosterone

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Femara, Lupron Depot, Gleevec, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Isotretinoin

Early Chemo May Boost Survival in Advanced Prostate Cancer

Posted 14 May 2015 by Drugs.com

THURSDAY, May 14, 2015 – Starting the chemotherapy drug docetaxel at the same time as hormone therapy can improve survival for men with newly diagnosed, advanced prostate cancer, British researchers say. Currently, chemotherapy is generally given after hormone therapy stops working. But the new study found that when the two therapies were paired at the start of treatment, patients lived an average of 10 months longer. The combination had even greater benefits for men whose prostate cancer had spread to other parts of their bodies – known as "metastatic" cancer. These men experienced an average 22-month improvement in their overall survival, the findings showed. "We hope our findings will encourage doctors to offer docetaxel to men newly diagnosed with metastatic prostate cancer, if they are healthy enough for chemotherapy," said lead author Dr. Nicholas James, director of the Cancer ... Read more

Related support groups: Lupron, Prostate Cancer, Lupron Depot, Reclast, Zoladex, Zometa, Zytiga, Taxotere, Eligard, Lupron Depot 3.75 mg, Zoledronic Acid, Aclasta, Xtandi, Leuprolide, Lupron Depot-PED, Degarelix, Trelstar, Docetaxel, Abiraterone, Supprelin

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