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Related terms: CREST Syndrome, Limited scleroderma, Progressive Systemic Sclerosis, Localized scleroderma, Morphea - linear

Stem Cell Transplant Shows Promise for Immune Disorder Scleroderma

Posted 17 days ago by Drugs.com

WEDNESDAY, Jan. 3, 2018 – Stem cell transplants could offer new hope for people with a severe form of scleroderma – a debilitating and deadly condition that affects the immune system, a new study suggests. "Scleroderma hardens the skin and connective tissues and, in its severe form, leads to fatal organ failure, most often the lungs," said the study's lead author, Dr. Keith Sullivan. He is a professor of medicine and cellular therapy at Duke University Medical Center. "In these severe cases, conventional drug therapies are not very effective long-term, so new approaches are a priority," Sullivan said in a hospital news release. Drugs to suppress the immune system are the standard of care in the United States for scleroderma with internal organ involvement, according to the researchers. Their study tested the effectiveness of stem cell transplant along with high-dose chemotherapy and ... Read more

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