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Global Efforts to Combat TB Epidemic Falling Short

Posted 13 Oct 2016 by Drugs.com

THURSDAY, Oct. 13, 2016 – Countries around the world need to work harder to combat tuberculosis infections and deaths, a new World Health Organization report says. Nations across the globe have pledged to reduce tuberculosis (TB) infections by 80 percent and TB deaths by 90 percent by 2030, but they must work faster if they want to meet these goals, according to the WHO. "We face an uphill battle to reach the global targets for tuberculosis," WHO Director General Dr. Margaret Chan said in an organization news release. "There must be a massive scale-up of efforts, or countries will continue to run behind this deadly epidemic and these ambitious goals will be missed." Tuberculosis is a disease that mainly affects the lungs. The bacteria that cause TB are primarily spread from person to person through tiny droplets from coughs and sneezes. The global response to the TB epidemic did manage ... Read more

Related support groups: Tuberculosis, Rifampin, Tuberculosis - Latent, Tuberculosis - Active, Ethambutol, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Pyrazinamide, Diagnosis and Investigation, Tuberculosis - Extrapulmonary, Rifamate, Isoniazid/Rifampin, Rifabutin, Mycobutin, Rifadin, Tuberculosis - HIV Negative, Tuberculosis - HIV Status Unknown, Tuberculous Meningitis, Myambutol, Rifater

Tuberculosis Decline in U.S. Has Stalled, CDC Reports

Posted 24 Mar 2016 by Drugs.com

THURSDAY, March 24, 2016 – Two decades of progress toward eliminating tuberculosis in the United States has stalled, with incidence of the lung disease holding steady from 2013 to 2015, a federal government report shows. "Resuming progress toward TB elimination in the United States will require intensification of efforts both in the U.S. and globally," said researchers from the U.S. Centers for Disease Control and Prevention's National Tuberculosis Surveillance System. If not treated, TB can be fatal. The bacterial infection is spread through the air, when someone infected coughs, sneezes or speaks. However, it is not easily transmitted – you must be in close contact with someone who has TB for a long period of time, according to the American Lung Association. Overall, TB incidence leveled off at about three new cases per 100,000 people each year between 2013 and 2015, according to ... Read more

Related support groups: Xifaxan, Tuberculosis, Rifampin, Rifaximin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Rifabutin, Isoniazid/Rifampin, Rifamate, Tuberculosis - HIV Negative, Rifater, Mycobutin, Tuberculosis - Resistant, Rifadin, Priftin, Isoniazid/Pyrazinamide/Rifampin, Rifadin IV

TB Cases Falling for Foreign-Born People in U.S.

Posted 10 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 10, 2016 – Tuberculosis cases among foreign-born people in the United States fell by one-fifth in recent years, and the reasons for the decline depend on people's country of origin, a new study suggests. Tuberculosis (TB) is a bacterial infection affecting the lungs and sometimes other organs. Overall, TB cases in the United States decreased over the past two decades, but TB cases among foreign-born people remained higher than in the general population, the study authors said. Between 2007 and 2011, there was a 19 percent drop in TB cases among all foreign-born people in the nation, according to researchers from the U.S. Centers for Disease Control and Prevention. TB cases declined in people recently arriving from Mexico, China, India, the Philippines and Vietnam – the five countries that account for most of the foreign-born people with TB in the United States, the ... Read more

Related support groups: Tuberculosis, Isoniazid, Rifampin, Tuberculosis - Latent, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Tuberculosis - Extrapulmonary, Isoniazid/Rifampin, Rifamate, Rifabutin, Tuberculous Meningitis, Rifater, Mycobutin, Tuberculosis - Resistant, Rifadin, Nydrazid, Rifadin IV, Tuberculosis - Urinary Tract, Isoniazid/Pyrazinamide/Rifampin

E-Pillboxes Improve Medication Adherence, Study Finds

Posted 15 Sep 2015 by Drugs.com

TUESDAY, Sept. 15, 2015 – Electronic reminders may help people with tuberculosis take their medication properly, a new study suggests. Tuberculosis (TB) patients are less likely to miss doses when they receive alerts from an electronic pillbox, researchers report in the Sept. 15 issue of PLOS Medicine. Electronic pillboxes use visual, audio and/or vibration cues to signal when it's time to take medication. TB is a bacterial infection that mainly strikes the lungs. The traditional method of ensuring medical adherence in TB patients is to watch people take their medicine, but the study authors said this isn't doable in remote areas such as rural China. "Innovative approaches to enable patients to adhere to TB treatment are needed. Widespread use of medication monitors in national TB control programs can benefit from the development of a low-cost and reliable medication monitor as well as ... Read more

Related support groups: Tuberculosis, Isoniazid, Rifampin, Ethambutol, Tuberculosis - Active, Pulmonary Tuberculosis, Tuberculosis - Prophylaxis, Pyrazinamide, Tuberculosis - Extrapulmonary, Isoniazid/Rifampin, Rifabutin, Rifamate, Mycobutin, Rifater, Myambutol, Rifadin, Priftin, Rifadin IV, Rifapentine, Isoniazid/Pyrazinamide/Rifampin

FDA Medwatch Alert: Colistimethate for Injection USP, 150 mg and Rifampin for Injection USP, 600 mg/vial by Heritage Pharmaceuticals: Recall - Lack of Sterility Assurance

Posted 25 Feb 2015 by Drugs.com

ISSUE: Heritage Pharmaceuticals Inc. announced the voluntary nationwide recall of ten (10) lots of Colistimethate for Injection, USP, 150 mg Single-Dose vial (NDC 23155-193-31) and three (3) lots of Rifampin for Injection, USP, 600 mg Single-Dose vial (NDC 23155-340-31) manufactured by Emcure Pharmaceuticals Ltd. and distributed by Heritage. Heritage has initiated this voluntary recall to the user level due to FDA observations pertaining to aseptic and GMP practices at the manufacturer's site potentially impacting product sterility. See the Press Release for a listing of affected lot numbers. Intravenous administration of non-sterile injection products to a normally sterile site may result in a site-specific or systemic infection, which in turn may cause hospitalization, significant morbidity (permanent organ damage), or fatal outcome. To date, Heritage is not aware of any adverse ... Read more

Related support groups: Infections, Rifampin, Colistimethate, Rifadin, Rifadin IV, Rimactane, Coly-Mycin M

New Test Detects TB and Antibiotic Resistance

Posted 26 Jul 2013 by Drugs.com

FRIDAY, July 26 – A new test to detect bacteria that cause tuberculosis and simultaneously determine if the bacteria are resistant to the antibiotic rifampin has been approved by the U.S. Food and Drug Administration. The Xpert MTB/RIF Assay is less complex to administer than other screening tests for TB. Results are available in about two hours, while traditional methods to detect TB could take up to several months, the agency said in a news release. People with weakened immune systems are most likely to develop full-blown TB once infected with the disease-causing bacteria, the FDA said. TB is a leading killer globally of people with HIV/AIDS. Common symptoms of TB include a severe cough lasting at least three weeks, chest pain, coughing up blood, fatigue and weight loss, the agency said. The test is manufactured and marketed by Cepheid, based in Sunnyvale, Calif. More information The ... Read more

Related support groups: Tuberculosis, Rifampin, Tuberculosis - Resistant, Rifadin, Rimactane, Rifadin IV

New Medicine Might Fight Drug-Resistant TB, Study Says

Posted 6 Jun 2012 by Drugs.com

WEDNESDAY, June 6 – More than four decades after the last introduction of fresh treatments for tuberculosis, a new medication for multidrug-resistant strains of the global scourge has shown promise in a multinational trial. Scientists in nine countries tested delamanid – which inhibits the production of mycolic acid, a key component of tuberculosis (TB) bacteria. In a phase 2 trial with 481 patients, the drug cleared TB from the sputum cultures of nearly half the patients within two months, the study said. "I think it's very important that we have, in delamanid, the potential for a new drug in the first class of new drugs in 40 years," said study co-author Lawrence Geiter, vice president of global clinical development for Otsuka Pharmaceutical Co., the Tokyo-based developer of delamanid. "It's going to enhance treatment options." The study is published June 7 in the New England ... Read more

Related support groups: Tuberculosis, Isoniazid, Rifampin, Rifadin, Rifadin IV, Rimactane, Nydrazid

TB Outbreaks in Texas Schools Show Disease Still a Threat

Posted 14 Oct 2011 by Drugs.com

FRIDAY, Oct. 14 – Outbreaks among young people in Texas of the old foe tuberculosis – often mistakenly dismissed as a long-ago health menace now confined to the pages of a Charles Dickens novel – show that the respiratory disease is still easily contracted and remains a potential threat to Americans, experts say. "Tuberculosis has always been with us and probably always will be," said Dr. Len Horovitz, a pulmonary specialist with Lenox Hill Hospital in New York City. At least 100 people have tested positive for tuberculosis (TB) on skin tests in Ennis, Texas, about 40 miles south of Dallas, including several students at the local high school. The testing was done after a teacher was diagnosed with TB before the start of the school year. And the University of North Texas in Denton – about 70 miles away – recommended that 27 people who had had contact with a student diagnosed with a ... Read more

Related support groups: Tuberculosis, Isoniazid, Rifampin, Ethambutol, Pyrazinamide, Rifadin, Myambutol, Rimactane, Nydrazid, Rifadin IV

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