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Propylthiouracil News

Thyroid Treatment Guidelines for Pregnant Women Revised

Posted 14 Aug 2012 by

TUESDAY, Aug. 14 – Thyroid hormone is critical for normal fetal brain development, and hormonal problems among pregnant women must be properly managed, according to the Endocrine Society, which just revised its guidelines on treating thyroid-related medical issues before, during and after pregnancy. Too much or not enough thyroid hormone can harm both women and their unborn babies, the experts ...

FDA Drug Safety Communication: New Boxed Warning on severe liver injury with propylthiouracil

Posted 22 Apr 2010 by

Safety Announcement Additional Information for Patients Additional Information for Healthcare Professionals Data Summary Safety Announcement [04-21-2010] The United States Food and Drug Administration (FDA) has added a Boxed Warning to the label for propylthiouracil, a drug used to treat hyperthyroidism (overactive thyroid), to include information about reports of severe liver injury and ...

FDA Medwatch Alert: Propylthiouracil

Posted 3 Jun 2009 by

FDA notified healthcare professionals of the risk of serious liver injury, including liver failure and death, with the use of propylthiouracil in adult and pediatric patients. Reports to FDA's Adverse Event Reporting System (AERS) suggest there is an increased risk of hepatotoxicity with proplythiouracil when compared to methimazole. FDA has identified 32 (AERS) cases (22 adult and 10 pediatric) ...

Drug May Be Dangerous for Kids With Graves' Disease

Posted 17 Apr 2009 by

FRIDAY, April 17 – A recommendation to restrict the use of the antithyroid drug (PTU) in children has been endorsed by the Endocrine Society. In a letter to the editor in the April 9 New England Journal of Medicine, two experts wrote that PTU can cause severe liver disease in children and should no longer be used as a first-line treatment for children with Graves' disease, a disorder in which ...

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Thyroid Storm, Hyperthyroidism, Alcoholic Liver Damage

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