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Related terms: Pre-Exposure Prophylaxis HIV Infection, PrEP, Reducing Risk of HIV Infection

Can HIV Drugs Boost Syphilis Risk?

Posted 22 hours ago by Drugs.com

MONDAY, Jan. 16, 2017 – Gay and bisexual men taking antiretroviral drugs to treat HIV infection may be at increased risk for syphilis, new research contends. Based on a review of available evidence, the investigators concluded that the drugs may boost susceptibility to the bacterium that causes syphilis, although the study did not prove cause-and-effect. The finding might explain why new and repeat cases of syphilis in gay and bisexual men have risen sharply compared to other sexually transmitted infections over the past decade, the researchers wrote. The study team was led by Dr. Michael Rekart, from the University of British Columbia's School of Population and Public Health in Vancouver. The findings were published in the Jan. 16 issue of the journal Sexually Transmitted Infections. The authors of an editorial that accompanied the study said the theory is "intriguing" and "warrants ... Read more

Related support groups: HIV Infection, Sexually Transmitted Diseases, Valtrex, Acyclovir, Tamiflu, Valacyclovir, Ribavirin, Pre-Exposure Prophylaxis, Incivek, Zovirax, Syphilis, Baraclude, Famciclovir, Victrelis, Famvir, Viread, Kaletra, Oseltamivir, Valcyte, Norvir

HIV May Double Odds of Heart Attack

Posted 22 Dec 2016 by Drugs.com

WEDNESDAY, Dec. 21, 2016 – As people with HIV are living longer, new concerns are cropping up, such as a risk for heart attack up to two times greater than for people without the AIDS-causing virus, a new study reports. Those increased odds are seen even in people whose virus has been suppressed to undetectable levels in the blood with antiretroviral drugs, the researchers said. There are several reasons for this higher risk, said lead researcher Dr. Matthew Feinstein, a cardiology fellow at Northwestern University Feinberg School of Medicine in Chicago. "A key factor appears to be chronic HIV-associated inflammation that persists even when there is no detectable virus in the blood," he said. Feinstein explained that the heart disease and stroke risk is higher "because the virus maintains a reservoir in the body's tissues, driving a chronic inflammatory and immune response that can ... Read more

Related support groups: Heart Attack, HIV Infection, Pre-Exposure Prophylaxis, Myocardial Infarction, Myocardial Infarction - Prophylaxis, Post MI Syndrome, Family History of Myocardial Infarction

Doctors Seeing More HIV Patients With Multidrug Resistance

Posted 1 Dec 2016 by Drugs.com

THURSDAY, Dec. 1, 2016 – A significant number of people with HIV have strains of the AIDS-causing virus that are resistant to both older and newer drugs, researchers report. The researchers looked at 712 HIV patients worldwide whose infection was not controlled by antiretroviral drugs. They found that 16 percent of patients whose infection was resistant to modern drugs had HIV mutations linked with resistance to older drugs called thymidine analogues. Among patients whose HIV had this mutation, 80 percent were also resistant to tenofovir, the main drug in most modern HIV treatment and prevention programs, the researchers reported. The findings were published in the Nov. 30 issue of The Lancet Infectious Diseases journal. "We were very surprised to see that so many people were resistant to both drugs, as we didn't think this was possible," study lead author Ravi Gupta, of University ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Sovaldi, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Zepatier, Genvoya, Epclusa, Sofosbuvir, Viread, Viekira Pak, Kaletra, Tenofovir

Use of Needle Exchange Programs Up Dramatically in 10 Years: CDC

Posted 30 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 30, 2016 – Although there was a significant increase in the use of syringe services programs (SSPs) – more commonly known as needle exchange programs – across the United States over the past decade, many injection drug users don't always use sterile needles, a federal government report says. Previously used needles put drug users at risk for infectious diseases such as HIV and hepatitis B and C, the report noted. Needle exchange programs provide sterile needles and syringes to injection drug users. These programs also refer drug users to prevention, care and treatment services. Researchers from the U.S. Centers for Disease Control and Prevention looked at data from injection drug users in 22 cities with high rates of HIV. In 2015, 54 percent of injection drug users said they used a needle exchange program in the past year. That was up significantly compared to the 36 ... Read more

Related support groups: Opiate Dependence, Hepatitis C, HIV Infection, Drug Dependence, Hepatitis B, Pre-Exposure Prophylaxis, Substance Abuse, Toxic Reactions Incl Drug and Substance Abuse, Hepatitis B Prevention, Exposure to Hepatitis B Virus, Hepatitis B Prophylaxis

Can Time-Release Capsules Replace Daily Pills?

Posted 16 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 16, 2016 – A new type of drug capsule might one day replace the need to take medicines every day, but so far it has only been tested in pigs, researchers report. A capsule that contains a six-armed star containing drugs can remain in the stomach and release its medication over time. That means instead of taking daily medication, patients would only have to swallow one capsule weekly or monthly, the researchers said. "We have the potential for an ultra-long capsule for medications that folks are currently taking once or twice or three times a day – that can now be given once a week or once a month," said researcher Dr. Giovanni Traverso. He is an instructor in the division of gastroenterology at Brigham and Women's Hospital in Boston. "This can make life a lot easier, because patients are more likely to take a medication when it's dosed once a week versus once a day," ... Read more

Related support groups: Schizophrenia, HIV Infection, Schizoaffective Disorder, Renal Failure, Alzheimer's Disease, Pre-Exposure Prophylaxis, Chronic Kidney Disease, Hyperphosphatemia of Renal Failure

Drug Combo Shows Early Promise for Remission of HIV

Posted 10 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – Animal research with an experimental two-drug therapy could hold clues for creating long-term HIV remission in people living with the virus, a new report says. The goal: to free patients from the need to take anti-HIV pills each day. Researchers combined an experimental vaccine with an immune-stimulating drug to create a one-two punch that caused a similar virus to become undetectable in three out of nine test monkeys, said senior author Dr. Dan Barouch. He's director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center in Boston. "Both of these components already are in clinical trials being conducted separately," Barouch said. "We hope to evaluate the combination in humans, and we plan to do further animal studies as well. The experimental vaccine, called Ad26/MVA, aims to help the immune system target HIV. The ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Diagnosis and Investigation

Antibodies May Hold Key to HIV Suppression

Posted 10 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – Antibodies may keep the HIV virus in check and one day let patients stop taking antiretroviral drugs, two new preliminary trials suggest. Researchers tried to quell HIV in 23 patients with infusions of an anti-HIV antibody known as VRC01. The antibody was safe and repressed blood levels of HIV for a short time before the virus reappeared, the researchers said. HIV is the virus that can lead to AIDS. "We were not expecting that we were going to see a prolonged repression, because it was only a single antibody," said co-study author Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases. The next phase is to infuse two or three antibodies intermittently, and see if antiretroviral drugs can be withdrawn permanently, he explained. After regular intravenous infusions of VRC01, participants in the U.S. National Institutes of ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Valacyclovir, Ribavirin, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Victrelis, Famciclovir, Famvir, Viread, Kaletra, Tenofovir, Ribasphere, Valcyte, Entecavir, Norvir, Copegus

HIV May Hide in Tissues, Even After Treatment

Posted 27 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 26, 2016 – HIV patients who've been treated with antiretroviral drugs still have the AIDS-causing virus in their tissues, a new study suggests. Treatment with antiretrovirals eliminates detectable levels of HIV in the blood and controls the disease. But the new findings suggest that HIV in the tissues may not cause AIDS but could contribute to the development of unrelated conditions, such as cancer and heart disease, according to the University of California, San Francisco (UCSF) researchers. "Looking in tissues of treated HIV patients, we found that HIV in some tissues did not appear to be affected by antiretrovirals," said study senior author Dr. Michael McGrath. "Notably we saw no evidence of drug resistance, which we would have seen if the virus had been exposed to medications," said McGrath. He is UCSF professor of laboratory medicine at the AIDS and Cancer ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Valacyclovir, Sovaldi, Ribavirin, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Victrelis, Famciclovir, Famvir, Sofosbuvir, Viread, Kaletra, Tenofovir, Ribasphere, Entecavir, Valcyte

Doctors May Not Be Telling High-Risk Patients About HIV Prevention Drug

Posted 10 Oct 2016 by Drugs.com

MONDAY, Oct. 10, 2016 – Many gay and bisexual men don't know about a drug therapy that can protect them from HIV, a new study suggests. A once-a-day pill, Truvada, known as PrEP – short for pre-exposure prophylaxis medication – has been found to reduce HIV infection by 92 percent in people at high risk for the AIDS-causing virus, including men who have unprotected gay sex, the researchers said. The researchers studied 2014 data from 401 HIV-negative gay and bisexual men in Baltimore. Only 42 percent knew about PrEP. Those who had been tested for HIV in the previous year were more likely to be aware of it. But having recently seen a doctor or getting tested for another sexually transmitted disease did not increase the likelihood that gay or bisexual men knew about the preventive drug, the researchers from the Johns Hopkins Bloomberg School of Public Health found. The findings suggest ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Truvada

Tips for Avoiding Back-to-School Germs, Illnesses

Posted 23 Sep 2016 by Drugs.com

FRIDAY, Sept. 23, 2016 – Kids and germs seem to go together like peanut butter and jelly. But, there are ways that parents can help protect their kids from the usual barrage of back-to-school illnesses, a health expert says. Make sure children get plenty of sleep and eat a well balanced diet, advises Jacqueline Stout-Aguilar. She's a registered nurse and an assistant professor at the Texas A&M College of Nursing. Most kids need at least nine hours of sleep each night, Stout-Aguilar said. It's also a good idea to make sure children get enough vitamin C to boost their immune system, she added. Parents should also teach their children how to contain germs and keep their hands clean. Show kids how to cover their coughs and sneezes with the inside of their elbow or a tissue, Stout-Aguilar said. She said kids must also be taught how to wash their hands properly. "It is important to wash your ... Read more

Related support groups: Influenza, Hepatitis B, Pre-Exposure Prophylaxis, Hepatitis A, Measles, Tetanus Toxoid, Rubella, FluLaval, Varicella Virus Vaccine, Pneumovax 23, Pneumococcal 23-polyvalent Vaccine, Afluria, Measles Virus Vaccine, Fluzone, FluMist, Kinrix, Mumps Virus Vaccine, Rubella Virus Vaccine, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, Boostrix (Tdap)

Opioids by Injection May Drive HIV Outbreaks

Posted 20 Jul 2016 by Drugs.com

WEDNESDAY, July 20, 2016 – The U.S. prescription drug abuse epidemic has increased the risk of HIV outbreaks in rural and suburban communities, where up to now the virus has posed little threat, warns a new case study. Needle-sharing among prescription drug addicts created an outbreak in rural Scott County, Ind. Public health officials report HIV infected 181 people there between November 2014 and November 2015. "It was the largest outbreak that has occurred in the U.S. since the introduction of HIV treatment," said lead author Dr. Philip Peters, a medical officer with the Division of HIV/AIDS Prevention at the U.S. Centers for Disease Control and Prevention. "And it occurred in a poor and rural community. We have not seen HIV outbreaks in these types of communities before." Many of the infected people had crushed and cooked down the extended-release form of the opioid pain pill ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, Opana, Opana ER, HIV Infection, Drug Dependence, Oxymorphone, Pre-Exposure Prophylaxis, Substance Abuse, Toxic Reactions Incl Drug and Substance Abuse, Numorphan, Numorphan HCl

Mixed Progress in Worldwide Fight Against HIV/AIDS

Posted 19 Jul 2016 by Drugs.com

TUESDAY, July 19, 2016 – The number of HIV/AIDS deaths worldwide each year has fallen since peaking in 2005, but the number of new HIV infections is up in 74 countries, according to a new study. Deaths from HIV/AIDS fell to 1.2 million in 2015 from 1.8 million in 2005. Though the number of new HIV infections has decreased since a peak of 3.3 million in 1997, it has been relatively stable at about 2.5 million a year for the past decade. Worldwide, new HIV infections fell just 0.7 percent a year between 2005 and 2015, compared to 2.7 percent a year between 1997 and 2005, the study found. Sub-Saharan Africa continued to be a trouble spot, accounting for three-quarters of new HIV infections (1.8 million) in 2015. Last year, south Asia had 8.5 percent (212,500) of new infections; southeast Asia, 4.7 percent (117,500); and east Asia, 2.3 percent (57,500). Between 2005 and 2015, the ... Read more

Related support groups: Infections, HIV Infection, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Baraclude, Victrelis, Viread, Oseltamivir, Kaletra, Tenofovir, Entecavir, Norvir, Lamivudine, Telaprevir, Reyataz, Nevirapine, Boceprevir, Prezista, Epivir

Monthly Vaginal Ring May Help Protect Against HIV

Posted 19 Jul 2016 by Drugs.com

MONDAY, July 18, 2016 – When used regularly, a medicated monthly vaginal ring may be an effective way for women in sub-Saharan Africa to protect themselves from HIV infection, according to new research. The flexible ring contains the antiretroviral drug dapivirine. The ring, developed by the nonprofit International Partnership for Microbicides (IPM), is placed high inside the vagina where it steadily releases the medication over the course of the month. Women insert the ring and remove it on their own. A Phase 3 trial, known as the ASPIRE study, involved more than 2,600 African women between the ages of 18 and 45. Researchers divided the women from Malawi, South Africa, Uganda and Zimbabwe into two groups. One group was assigned to use the dapivirine ring and the other group to use a placebo ring that contained no medication. Between August 2012 and June 2015, 27 percent fewer women in ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis

Cash Rewards Won't Change Outcomes for HIV-Infected Drug Addicts: Study

Posted 14 Jul 2016 by Drugs.com

WEDNESDAY, July 13, 2016 – Giving drug-addicted, HIV-positive people cash incentives to help improve unhealthy behaviors doesn't work, a new study finds. The study, funded by the U.S. National Institute on Drug Abuse, tracked outcomes for HIV-infected people with substance-abuse problems – a notoriously tough group to treat, the researchers said. To lower rates of HIV infection and illness, "we must get serious about hard-to-reach populations" like these, lead researcher Lisa Metsch, of Columbia University in New York City, explained in a university news release. Giving people cash rewards for healthy improvements in behavior – for example, exercising or stopping smoking – has been somewhat successful for other patient populations. So, Metsch's group wondered if a similar approach might help HIV-infected people battling drug or alcohol abuse. To find out, the investigators tracked ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, HIV Infection, Drug Dependence, Pre-Exposure Prophylaxis, Toxic Reactions Incl Drug and Substance Abuse

How Safe Is Condomless Sex When Partner With HIV Takes Meds?

Posted 13 Jul 2016 by Drugs.com

TUESDAY, July 12, 2016 – HIV transmission is highly unlikely among straight couples who have sex without condoms when one partner carries the virus but takes medication, new research suggests. For gay couples in the same scenario, the risk seems to be only slightly higher. The Danish study had some major limitations. It only tracked couples for up to two years, and there's no way to know if the risk of HIV transmission will grow over time as couples age. Also, the HIV-positive participants were almost always careful to take their medication. And at least one AIDS prevention expert expressed some caution about the study's conclusions. Still, "it [the study's findings] is really great news for patients and their partners," said HIV specialist Dr. Jared Baeten, vice chair of global health at the University of Washington in Seattle. He was not involved with the study but is familiar with ... Read more

Related support groups: HIV Infection, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis

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