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Related terms: Pre-Exposure Prophylaxis HIV Infection, PrEP, Reducing Risk of HIV Infection

Doctors Seeing More HIV Patients With Multidrug Resistance

Posted 1 day 22 hours ago by Drugs.com

THURSDAY, Dec. 1, 2016 – A significant number of people with HIV have strains of the AIDS-causing virus that are resistant to both older and newer drugs, researchers report. The researchers looked at 712 HIV patients worldwide whose infection was not controlled by antiretroviral drugs. They found that 16 percent of patients whose infection was resistant to modern drugs had HIV mutations linked with resistance to older drugs called thymidine analogues. Among patients whose HIV had this mutation, 80 percent were also resistant to tenofovir, the main drug in most modern HIV treatment and prevention programs, the researchers reported. The findings were published in the Nov. 30 issue of The Lancet Infectious Diseases journal. "We were very surprised to see that so many people were resistant to both drugs, as we didn't think this was possible," study lead author Ravi Gupta, of University ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Sovaldi, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Genvoya, Sofosbuvir, Zepatier, Viread, Viekira Pak, Kaletra, Entecavir, Tenofovir

Use of Needle Exchange Programs Up Dramatically in 10 Years: CDC

Posted 2 days 20 hours ago by Drugs.com

WEDNESDAY, Nov. 30, 2016 – Although there was a significant increase in the use of syringe services programs (SSPs) – more commonly known as needle exchange programs – across the United States over the past decade, many injection drug users don't always use sterile needles, a federal government report says. Previously used needles put drug users at risk for infectious diseases such as HIV and hepatitis B and C, the report noted. Needle exchange programs provide sterile needles and syringes to injection drug users. These programs also refer drug users to prevention, care and treatment services. Researchers from the U.S. Centers for Disease Control and Prevention looked at data from injection drug users in 22 cities with high rates of HIV. In 2015, 54 percent of injection drug users said they used a needle exchange program in the past year. That was up significantly compared to the 36 ... Read more

Related support groups: Opiate Dependence, Hepatitis C, HIV Infection, Drug Dependence, Hepatitis B, Pre-Exposure Prophylaxis, Substance Abuse, Toxic Reactions Incl Drug and Substance Abuse, Hepatitis B Prevention, Exposure to Hepatitis B Virus, Hepatitis B Prophylaxis

Can Time-Release Capsules Replace Daily Pills?

Posted 17 days ago by Drugs.com

WEDNESDAY, Nov. 16, 2016 – A new type of drug capsule might one day replace the need to take medicines every day, but so far it has only been tested in pigs, researchers report. A capsule that contains a six-armed star containing drugs can remain in the stomach and release its medication over time. That means instead of taking daily medication, patients would only have to swallow one capsule weekly or monthly, the researchers said. "We have the potential for an ultra-long capsule for medications that folks are currently taking once or twice or three times a day – that can now be given once a week or once a month," said researcher Dr. Giovanni Traverso. He is an instructor in the division of gastroenterology at Brigham and Women's Hospital in Boston. "This can make life a lot easier, because patients are more likely to take a medication when it's dosed once a week versus once a day," ... Read more

Related support groups: Schizophrenia, HIV Infection, Schizoaffective Disorder, Renal Failure, Alzheimer's Disease, Pre-Exposure Prophylaxis, Chronic Kidney Disease, Hyperphosphatemia of Renal Failure

Drug Combo Shows Early Promise for Remission of HIV

Posted 10 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – Animal research with an experimental two-drug therapy could hold clues for creating long-term HIV remission in people living with the virus, a new report says. The goal: to free patients from the need to take anti-HIV pills each day. Researchers combined an experimental vaccine with an immune-stimulating drug to create a one-two punch that caused a similar virus to become undetectable in three out of nine test monkeys, said senior author Dr. Dan Barouch. He's director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center in Boston. "Both of these components already are in clinical trials being conducted separately," Barouch said. "We hope to evaluate the combination in humans, and we plan to do further animal studies as well. The experimental vaccine, called Ad26/MVA, aims to help the immune system target HIV. The ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Diagnosis and Investigation

Antibodies May Hold Key to HIV Suppression

Posted 10 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – Antibodies may keep the HIV virus in check and one day let patients stop taking antiretroviral drugs, two new preliminary trials suggest. Researchers tried to quell HIV in 23 patients with infusions of an anti-HIV antibody known as VRC01. The antibody was safe and repressed blood levels of HIV for a short time before the virus reappeared, the researchers said. HIV is the virus that can lead to AIDS. "We were not expecting that we were going to see a prolonged repression, because it was only a single antibody," said co-study author Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases. The next phase is to infuse two or three antibodies intermittently, and see if antiretroviral drugs can be withdrawn permanently, he explained. After regular intravenous infusions of VRC01, participants in the U.S. National Institutes of ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Valacyclovir, Ribavirin, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Victrelis, Famciclovir, Famvir, Viread, Kaletra, Ribasphere, Valcyte, Entecavir, Norvir, Copegus, Tenofovir

HIV May Hide in Tissues, Even After Treatment

Posted 27 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 26, 2016 – HIV patients who've been treated with antiretroviral drugs still have the AIDS-causing virus in their tissues, a new study suggests. Treatment with antiretrovirals eliminates detectable levels of HIV in the blood and controls the disease. But the new findings suggest that HIV in the tissues may not cause AIDS but could contribute to the development of unrelated conditions, such as cancer and heart disease, according to the University of California, San Francisco (UCSF) researchers. "Looking in tissues of treated HIV patients, we found that HIV in some tissues did not appear to be affected by antiretrovirals," said study senior author Dr. Michael McGrath. "Notably we saw no evidence of drug resistance, which we would have seen if the virus had been exposed to medications," said McGrath. He is UCSF professor of laboratory medicine at the AIDS and Cancer ... Read more

Related support groups: HIV Infection, Valtrex, Acyclovir, Sovaldi, Valacyclovir, Ribavirin, Pre-Exposure Prophylaxis, Incivek, Zovirax, Baraclude, Victrelis, Famciclovir, Famvir, Sofosbuvir, Viread, Kaletra, Diagnosis and Investigation, Entecavir, Ribasphere, Valcyte

Doctors May Not Be Telling High-Risk Patients About HIV Prevention Drug

Posted 10 Oct 2016 by Drugs.com

MONDAY, Oct. 10, 2016 – Many gay and bisexual men don't know about a drug therapy that can protect them from HIV, a new study suggests. A once-a-day pill, Truvada, known as PrEP – short for pre-exposure prophylaxis medication – has been found to reduce HIV infection by 92 percent in people at high risk for the AIDS-causing virus, including men who have unprotected gay sex, the researchers said. The researchers studied 2014 data from 401 HIV-negative gay and bisexual men in Baltimore. Only 42 percent knew about PrEP. Those who had been tested for HIV in the previous year were more likely to be aware of it. But having recently seen a doctor or getting tested for another sexually transmitted disease did not increase the likelihood that gay or bisexual men knew about the preventive drug, the researchers from the Johns Hopkins Bloomberg School of Public Health found. The findings suggest ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Truvada

Tips for Avoiding Back-to-School Germs, Illnesses

Posted 23 Sep 2016 by Drugs.com

FRIDAY, Sept. 23, 2016 – Kids and germs seem to go together like peanut butter and jelly. But, there are ways that parents can help protect their kids from the usual barrage of back-to-school illnesses, a health expert says. Make sure children get plenty of sleep and eat a well balanced diet, advises Jacqueline Stout-Aguilar. She's a registered nurse and an assistant professor at the Texas A&M College of Nursing. Most kids need at least nine hours of sleep each night, Stout-Aguilar said. It's also a good idea to make sure children get enough vitamin C to boost their immune system, she added. Parents should also teach their children how to contain germs and keep their hands clean. Show kids how to cover their coughs and sneezes with the inside of their elbow or a tissue, Stout-Aguilar said. She said kids must also be taught how to wash their hands properly. "It is important to wash your ... Read more

Related support groups: Influenza, Hepatitis B, Pre-Exposure Prophylaxis, Hepatitis A, Measles, Tetanus Toxoid, Rubella, FluLaval, Varicella Virus Vaccine, Pneumococcal 23-polyvalent Vaccine, Afluria, Measles Virus Vaccine, Pneumovax 23, Fluzone, FluMist, Kinrix, Mumps Virus Vaccine, Rubella Virus Vaccine, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine/Varicella Virus Vaccine, Measles Virus Vaccine/Mumps Virus Vaccine/Rubella Virus Vaccine

Opioids by Injection May Drive HIV Outbreaks

Posted 20 Jul 2016 by Drugs.com

WEDNESDAY, July 20, 2016 – The U.S. prescription drug abuse epidemic has increased the risk of HIV outbreaks in rural and suburban communities, where up to now the virus has posed little threat, warns a new case study. Needle-sharing among prescription drug addicts created an outbreak in rural Scott County, Ind. Public health officials report HIV infected 181 people there between November 2014 and November 2015. "It was the largest outbreak that has occurred in the U.S. since the introduction of HIV treatment," said lead author Dr. Philip Peters, a medical officer with the Division of HIV/AIDS Prevention at the U.S. Centers for Disease Control and Prevention. "And it occurred in a poor and rural community. We have not seen HIV outbreaks in these types of communities before." Many of the infected people had crushed and cooked down the extended-release form of the opioid pain pill ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, Opana, Opana ER, HIV Infection, Drug Dependence, Oxymorphone, Pre-Exposure Prophylaxis, Substance Abuse, Toxic Reactions Incl Drug and Substance Abuse, Numorphan, Numorphan HCl

Mixed Progress in Worldwide Fight Against HIV/AIDS

Posted 19 Jul 2016 by Drugs.com

TUESDAY, July 19, 2016 – The number of HIV/AIDS deaths worldwide each year has fallen since peaking in 2005, but the number of new HIV infections is up in 74 countries, according to a new study. Deaths from HIV/AIDS fell to 1.2 million in 2015 from 1.8 million in 2005. Though the number of new HIV infections has decreased since a peak of 3.3 million in 1997, it has been relatively stable at about 2.5 million a year for the past decade. Worldwide, new HIV infections fell just 0.7 percent a year between 2005 and 2015, compared to 2.7 percent a year between 1997 and 2005, the study found. Sub-Saharan Africa continued to be a trouble spot, accounting for three-quarters of new HIV infections (1.8 million) in 2015. Last year, south Asia had 8.5 percent (212,500) of new infections; southeast Asia, 4.7 percent (117,500); and east Asia, 2.3 percent (57,500). Between 2005 and 2015, the ... Read more

Related support groups: Infections, HIV Infection, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Baraclude, Victrelis, Viread, Kaletra, Oseltamivir, Tenofovir, Entecavir, Norvir, Telaprevir, Nevirapine, Lamivudine, Boceprevir, Prezista, Reyataz, Lexiva

Monthly Vaginal Ring May Help Protect Against HIV

Posted 19 Jul 2016 by Drugs.com

MONDAY, July 18, 2016 – When used regularly, a medicated monthly vaginal ring may be an effective way for women in sub-Saharan Africa to protect themselves from HIV infection, according to new research. The flexible ring contains the antiretroviral drug dapivirine. The ring, developed by the nonprofit International Partnership for Microbicides (IPM), is placed high inside the vagina where it steadily releases the medication over the course of the month. Women insert the ring and remove it on their own. A Phase 3 trial, known as the ASPIRE study, involved more than 2,600 African women between the ages of 18 and 45. Researchers divided the women from Malawi, South Africa, Uganda and Zimbabwe into two groups. One group was assigned to use the dapivirine ring and the other group to use a placebo ring that contained no medication. Between August 2012 and June 2015, 27 percent fewer women in ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis

Cash Rewards Won't Change Outcomes for HIV-Infected Drug Addicts: Study

Posted 14 Jul 2016 by Drugs.com

WEDNESDAY, July 13, 2016 – Giving drug-addicted, HIV-positive people cash incentives to help improve unhealthy behaviors doesn't work, a new study finds. The study, funded by the U.S. National Institute on Drug Abuse, tracked outcomes for HIV-infected people with substance-abuse problems – a notoriously tough group to treat, the researchers said. To lower rates of HIV infection and illness, "we must get serious about hard-to-reach populations" like these, lead researcher Lisa Metsch, of Columbia University in New York City, explained in a university news release. Giving people cash rewards for healthy improvements in behavior – for example, exercising or stopping smoking – has been somewhat successful for other patient populations. So, Metsch's group wondered if a similar approach might help HIV-infected people battling drug or alcohol abuse. To find out, the investigators tracked ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, HIV Infection, Drug Dependence, Pre-Exposure Prophylaxis, Toxic Reactions Incl Drug and Substance Abuse

How Safe Is Condomless Sex When Partner With HIV Takes Meds?

Posted 13 Jul 2016 by Drugs.com

TUESDAY, July 12, 2016 – HIV transmission is highly unlikely among straight couples who have sex without condoms when one partner carries the virus but takes medication, new research suggests. For gay couples in the same scenario, the risk seems to be only slightly higher. The Danish study had some major limitations. It only tracked couples for up to two years, and there's no way to know if the risk of HIV transmission will grow over time as couples age. Also, the HIV-positive participants were almost always careful to take their medication. And at least one AIDS prevention expert expressed some caution about the study's conclusions. Still, "it [the study's findings] is really great news for patients and their partners," said HIV specialist Dr. Jared Baeten, vice chair of global health at the University of Washington in Seattle. He was not involved with the study but is familiar with ... Read more

Related support groups: Sexually Transmitted Diseases, HIV Infection, Pre-Exposure Prophylaxis

Do More to Fight HIV in Africa: Study

Posted 13 Jul 2016 by Drugs.com

TUESDAY, July 12, 2016 – New HIV infections in African men could be prevented by increasing male circumcision rates and providing more women with HIV antiretroviral therapy (ART), a new study finds. Researchers said these strategies were linked to a considerable drop in the number of men newly infected with HIV in specific communities in rural Uganda. "The biology of these two prevention strategies has been proven, but the big question was whether these strategies could have an impact on the number of new HIV infections in communities still struggling to control the spread of the disease," said study leader Xiangrong Kong. She is an associate scientist in epidemiology and biostatistics at Johns Hopkins' Bloomberg School of Public Health in Baltimore. "Before our study, there was no empirical data to show the effects of scaling up these two interventions in real-world settings. It's ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis

Stigma Prolongs Global HIV Epidemic Among Gays

Posted 8 Jul 2016 by Drugs.com

THURSDAY, July 7, 2016 – High rates of HIV among gay and bisexual men continue in many regions of the world because of discriminatory laws and lack of access to preventive services, a new study finds. "While HIV rates have flattened overall in recent years, we're really concerned that the HIV epidemic is continuing among gay men and we're going in the wrong direction," said study leader Dr. Chris Beyrer, a professor of public health and human rights at the Johns Hopkins Bloomberg School of Public Health in Baltimore. "It's painful that the history of AIDS is looking like its future, but that's actually where we are," said Beyrer, who is also president of the International AIDS Society. "But the first step in taking on a problem is recognizing and articulating it, and we've really done that here." Four years ago, the same researchers laid out a plan to curb HIV epidemics in gays. Among ... Read more

Related support groups: Sexually Transmitted Diseases, HIV Infection, Pre-Exposure Prophylaxis

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