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Related terms: Bubonic plague, Pneumonic plague, Septicemic plague

Rats May Not Have Driven the Black Death Plague After All

Posted 16 Jan 2018 by Drugs.com

TUESDAY, Jan. 16, 2018 – It's thought to have killed between 30 and 60 percent of Europe's population, but the Black Death plague may not have been spread by flea-infested rats, Norwegian scientists report. Between its first devastating outbreak in the 14th century, and finally fading away by the 1800s, the plague caused by the Yersinia pestis bacterium sent millions of Europeans to early ...

Health Highlights: Aug. 14, 2017

Posted 14 Aug 2017 by Drugs.com

Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Fleas Test Positive for Plague in Arizona Health officials from two counties in northern Arizona are warning the public that fleas are testing positive for the Yersinia pestis bacterium that causes plague. Following a similar announcement from the Coconino County Public Health Services ...

6th-Century Skeletons Shed Light on Deadly Plague Outbreaks

Posted 4 Sep 2016 by Drugs.com

FRIDAY, Sept. 2, 2016 – Ancient skeletons have helped scientists learn more about plague, and the discoveries could prove important in future outbreaks. Centuries before the Black Death in the 1300s, the Justinian plague in the sixth century killed about 50 million people (15 percent of the world's population) across the Byzantine Empire. German scientists have now confirmed that both outbreaks ...

FDA Medwatch Alert: Fluoroquinolone Antibacterial Drugs for Systemic Use: Drug Safety Communication - Warnings Updated Due to Disabling Side Effects

Posted 26 Jul 2016 by Drugs.com

ISSUE: FDA approved changes to the labels of fluoroquinolone antibacterial drugs for systemic use (i.e., taken by mouth or by injection). Includes the following currently available fluoroquinolones: Avelox (moxifloxacin) Cipro (ciprofloxacin) Cipro extended-release (ciprofloxacin extended-release) Factive (gemifloxacin) Levaquin (levofloxacin) Ofloxacin (generic brand) These medicines are ...

FDA Updates Warnings for Fluoroquinolone Antibiotics

Posted 26 Jul 2016 by Drugs.com

July 26, 2016 – The U.S. Food and Drug Administration today approved safety labeling changes for a class of antibiotics, called fluoroquinolones, to enhance warnings about their association with disabling and potentially permanent side effects and to limit their use in patients with less serious bacterial infections. “Fluoroquinolones have risks and benefits that should be considered very c ...

Researchers ID Areas of Western U.S. With Risk of Plague

Posted 31 Dec 2015 by Drugs.com

THURSDAY, Dec. 31, 2015 – Parts of central Colorado, north-central New Mexico and southwestern and northeastern California have the highest risk for human exposure to plague, new research suggests. The scientists said their findings, which are based on cases of plague reported in both wild and domestic animals between 2000 and 2015, could help public health officials better monitor the ...

Plague May Have Infected Humans Earlier Than Thought

Posted 22 Oct 2015 by Drugs.com

THURSDAY, Oct. 22, 2015 – Plague infected humans thousands of years earlier than previously believed, a new study suggests. Researchers analyzed DNA from the teeth of Bronze Age human remains in Europe and Asia and found signs of plague infections about 4,800 years ago. That is 3,300 years earlier than prior evidence. But it was at least another thousand years before the plague-causing Yersinia ...

Did One Gene Mutation Launch the Black Death?

Posted 30 Jun 2015 by Drugs.com

TUESDAY, June 30, 2015 – One small genetic change may have transformed Yersinia pestis – the plague bacteria – from a relatively mild germ into the deadly bug that killed millions in the Black Death and other historic epidemics, scientists report. According to the U.S. Centers for Disease Control and Prevention, humans can contract Y. pestis after being bitten by a flea carried by a rodent or ...

Avelox Approved for Plague

Posted 10 May 2015 by Drugs.com

FRIDAY, May 8, 2015 – Avelox (moxifloxacin) was approved by the U.S. Food and Drug Administration on Friday to treat plague, a rare but deadly bacterial infection that can strike the lungs (pneumonic), blood (septicemic) or lymph nodes (bubonic). Only 1,000 to 2,000 cases are reported worldwide annually, the agency said in a news release. It's spread by the bites of infected fleas, or by contact ...

FDA Approves Avelox (moxifloxacin) as Additional Antibacterial Treatment for Plague

Posted 8 May 2015 by Drugs.com

May 8, 2015 - The U.S. Food and Drug Administration today approved Avelox (moxifloxacin) to treat patients with plague, a rare and potentially fatal bacterial infection. The agency approval for plague includes use of the drug for the treatment of pneumonic plague (infection of the lungs), and septicemic plague (infection of the blood). Avelox is also approved for prevention of plague in adult ...

Colorado Dog Key to U.S. Plague Outbreak, Study Confirms

Posted 30 Apr 2015 by Drugs.com

THURSDAY, April 30, 2015 – A Colorado dog last year caused the largest outbreak of pneumonic plague – also called the Black Death – in the United States since 1924, scientists reported Thursday. Four people, including the dog's owner, ended up contracting the rare and potentially deadly infection, Colorado public health officials reported. Their findings were published in the May 1 issue of ...

New York City Rats Carry Fleas Known to Transmit Plague

Posted 2 Mar 2015 by Drugs.com

MONDAY, March 2, 2015 – Rats in New York City are brimming with fleas and other parasites that can carry a number of diseases, including the plague, a new study reports. Researchers analyzed 6,500 specimens of five well-known species of fleas, lice and mites found on over 130 rats from around the city. The samples included Oriental rat fleas, a type of flea that can transmit bubonic plague, also ...

Plague Rare in U.S., Surfacing in More Affluent Areas

Posted 13 Jun 2012 by Drugs.com

WEDNESDAY, June 13 – Although the plague is typically considered a remnant of the Middle Ages, when unsanitary conditions and rodent infestations prevailed amid the squalor of poverty, this rare but deadly disease appears to be spreading through wealthier communities in New Mexico, researchers report. Why the plague is popping up in affluent neighborhoods isn't completely clear, the experts ...

FDA Approves Levaquin as an Antibacterial Treatment for Plague

Posted 30 Apr 2012 by Drugs.com

April 27, 2012 – The U.S. Food and Drug Administration today approved Levaquin (levofloxacin) to treat patients with plague, a rare and potentially deadly bacterial infection. The agency also approved the drug to reduce the risk of getting plague after exposure to Yersinia pestis, the bacterium that causes the disease. Plague is extremely rare in most parts of the world, including the United ...

Levaquin Approved to Treat or Prevent Plague

Posted 27 Apr 2012 by Drugs.com

FRIDAY, April 27 – Approval of the antibiotic Levaquin (levofloxacin) has been expanded by the U.S. Food and Drug Administration to include plague, a rare but deadly bacterial infection. The disease is extremely rare in the United States, and only about 1,000 to 2,000 cases occur each year across the globe, the agency said in a news release. The three most common forms of plague include bubonic ...

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