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Cooling Mitts, Socks May Ease a Major Chemo Side Effect

Posted 18 Oct 2017 by Drugs.com

WEDNESDAY, Oct. 18, 2017 – Many cancer drugs can cause debilitating nerve damage as a side effect. But a small study suggests that simple cold wraps to the hands and feet might prevent it. The side effect, known as peripheral neuropathy, damages nerves in the limbs. This often leads to pain, numbness and tingling, and difficulty with balance and using the hands and fingers. There are treatments for peripheral neuropathy, according to the American Cancer Society. But there are no proven ways to prevent it. In the new study, researchers tested a simple tactic: having patients wear frozen gloves and socks during chemotherapy. With that protection in place, patients were much less likely to develop symptoms of nerve damage, the study found. Medical experts said there are reasons to be excited about the findings. For one, the therapy is "easy and safe," said study leader Akiko Hanai, an ... Read more

Related support groups: Cancer, Peripheral Neuropathy, Taxol, Taxotere, Cisplatin, Carboplatin, Cytoxan, Bendamustine, Cyclophosphamide, Temodar, Paclitaxel, Oxaliplatin, Treanda, Vincristine, Leukeran, Vinblastine, Alkeran, Docetaxel, Platinol, Neosar

Marijuana May Help Ease Nerve Pain, Review Finds

Posted 14 Aug 2017 by Drugs.com

MONDAY, Aug. 14, 2017 – Marijuana may be slightly effective at reducing chronic nerve pain known as neuropathy. But there's little evidence on whether or not pot helps treat other types of pain or post-traumatic stress disorder (PTSD), a pair of new studies suggests. The findings on neuropathy "fit generally well with what we know," said Dr. Sachin Patel of the Vanderbilt Psychiatric Hospital in Nashville. Patel wrote a commentary accompanying the review in the Aug. 15 online edition of Annals of Internal Medicine. Medical marijuana is legal in almost all states and the District of Columbia for certain medical purposes. Some states may have laws that haven't yet been implemented, according to NORML, a pro-marijuana legalization group. But research into the medical uses of marijuana remains controversial. Plus, it's difficult for scientists to study the drug because it is illegal on the ... Read more

Related support groups: Post Traumatic Stress Disorder, Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Nerve Damage, Small Fiber Neuropathy, Cannabis, Autonomic Neuropathy

Blame Diabetes: Rates of 2 Nerve Conditions on the Rise

Posted 21 Jul 2017 by Drugs.com

FRIDAY, July 21, 2017 – Two particular types of nerve damage (neuropathy) have been increasing as more and more people develop diabetes in the United States, an expert says. Autonomic and small fiber neuropathy were once rare conditions. Both occur when small blood vessels supplying the nerves are damaged by diabetes because they don't get enough oxygen and nutrients, said Dr. Divpreet Kaur, a neurologist at Penn State Health Milton S. Hershey Medical Center. Diabetes is one of the main causes of neuropathy, and about 30 million Americans currently have diabetes, Kaur said. More commonly, people with diabetes have nerve damage that causes numbness in the feet and toes. This is called peripheral neuropathy, according to the American Diabetes Association. Autonomic neuropathy affects involuntary bodily functions such as blood pressure, digestion, sexual function, urination, temperature ... Read more

Related support groups: Diabetes, Type 2, Metformin, Peripheral Neuropathy, Insulin, Lantus, Diabetes, Type 1, Diabetic Neuropathy, Glipizide, Novolog, Diabetic Nerve Damage, Humalog, Glucophage, Insulin Resistance, Invokana, Janumet, Glyburide, Lantus Solostar, Levemir, Pre-Diabetes, Actos

What Drugs Work Best for Diabetic Nerve Pain?

Posted 25 Mar 2017 by Drugs.com

FRIDAY, March 24, 2017 – Nerve pain and numbness, also known as neuropathy, is a debilitating but common symptom of diabetes. Now, new research suggests certain drugs may outperform others in treating diabetic neuropathy. The new review of the data on the subject was led by Julie Waldfogel of Johns Hopkins Hospital in Baltimore. Her team noted that about half of people with diabetes have some form of nerve damage caused by high levels of blood sugar. However, not all of them will have symptoms such as pain, numbness and tingling in the legs and feet. In the new study, the Hopkins group reviewed 106 studies on pain relief for diabetic neuropathy. The researchers found "moderate" evidence that the antidepressants duloxetine (Cymbalta) and venlafaxine (Effexor) reduce diabetic nerve pain. However, they only found "weak" evidence that botulinum toxin (Botox), the anti-seizure drugs ... Read more

Related support groups: Diabetes, Type 2, Cymbalta, Gabapentin, Effexor, Peripheral Neuropathy, Venlafaxine, Effexor XR, Neurontin, Diabetes, Type 1, Diabetic Neuropathy, Duloxetine, Diabetic Nerve Damage, Gralise, Capsaicin, Valproic Acid, Diabetes Mellitus, Depakene, Capzasin, Pain Doctor, Terocin

Brain Training for Cancer Survivors' Nerve Damage

Posted 5 Mar 2017 by Drugs.com

FRIDAY, March 3, 2017 – Learning to control their brain waves with a type of training called neurofeedback seems to help cancer survivors ease symptoms of chemotherapy-caused nerve damage, a new study suggests. Chemotherapy can damage nerves that control sensation and movement in the arms and legs. This condition – called chronic chemotherapy-induced peripheral neuropathy (CIPN) – affects up to 96 percent of patients within a month of chemo. Symptoms include pain, burning, tingling and loss of feeling, the study authors explained. "There is currently only one approved medication to treat CIPN and it has associated muscle aches and nausea. Neurofeedback has no known negative side effects, can be used in combinations with other treatments and is reasonably cost-effective," said study lead investigator Sarah Prinsloo. She is an assistant professor in the Division of Cancer Medicine at ... Read more

Related support groups: Cancer, Muscle Pain, Peripheral Neuropathy

FDA Bolsters Warnings About Class of Antibiotics

Posted 26 Jul 2016 by Drugs.com

TUESDAY, July 26, 2016 – The U.S. Food and Drug Administration announced Tuesday that it's strengthening label warnings on a class of antibiotics called fluoroquinolones because the drugs can lead to disabling side effects, including long-term nerve damage and ruptured tendons. The agency also cautioned that these bacteria-fighting drugs – including levofloxacin (Levaquin) and ciprofloxacin (Cipro) – shouldn't be prescribed for sinusitis, chronic bronchitis or simple urinary tract infections unless no other treatments options exist. "Fluoroquinolones have risks and benefits that should be considered very carefully," Dr. Edward Cox said in an FDA news release. He's director of the Office of Antimicrobial Products at the FDA's Center for Drug Evaluation and Research. "It's important that both health care providers and patients are aware of both the risks and benefits of ... Read more

Related support groups: Infections, Urinary Tract Infection, Peripheral Neuropathy, Sinusitis, Bladder Infection, Cipro, Bronchitis, Ciprofloxacin, Levaquin, Levofloxacin, Kidney Infections, Myasthenia Gravis, Avelox, Ofloxacin, Vigamox, Ciprodex, Sinus Symptoms, Moxifloxacin, Norfloxacin, Gatifloxacin

HIV Infection Seems to Affect Nervous System

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – Many newly infected HIV patients experience neurological problems, but they tend to be mild and they subside after antiretroviral drugs are given, a new study finds. "We were surprised that neurologic findings were so pervasive in participants diagnosed with very recent HIV infection," said study author Dr. Joanna Hellmuth. She is a clinical fellow in the department of neurology at the University of California, San Francisco (UCSF). "While the findings were mild, it is clear that HIV affects the nervous system within days of infection," she said in a university news release. "Since the majority of these neurologic issues were resolved with treatment, our study reinforces recommendations that people at risk for HIV test often and start antiretroviral treatment immediately if they are infected," Hellmuth added. Among 139 people in Thailand infected with HIV three ... Read more

Related support groups: Peripheral Neuropathy, Harvoni, HIV Infection, Pre-Exposure Prophylaxis, Atripla, Incivek, Truvada, Triumeq, Stribild, Zepatier, Autonomic Neuropathy, Complera, Genvoya, Victrelis, Baraclude, Viread, Norvir, Prezista, Tenofovir, Kaletra

Prediabetes May Damage Nerves More Than Thought

Posted 12 Apr 2016 by Drugs.com

TUESDAY, April 12, 2016 – Prediabetes may cause more nerve damage than previously believed, researchers say. "The results of this new study add urgency to the need for more screening of those with the condition and faster intervention," said senior study author Dr. Michael Polydefkis, a professor of neurology at Johns Hopkins University School of Medicine. The study included 62 people, including 52 with tingling and pain in their hands and feet – a condition known as neuropathy. Diabetes is a common cause of neuropathy, the researchers said. Thirteen participants had prediabetes, meaning their blood sugar levels were higher than normal but not yet at the point of diabetes. Over three years, the researchers found that those with prediabetes had damage over the entire length of small sensory nerve fibers, rather than just at the longest ends first. The findings challenge current ... Read more

Related support groups: Diabetes, Type 2, Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Nerve Damage, Insulin Resistance, Pre-Diabetes, Small Fiber Neuropathy, Diabetes Mellitus, Abnormal Glucose Tolerance

Nerve Damage From Chemo May Affect Cancer Survivors for Years

Posted 15 Jan 2016 by Drugs.com

FRIDAY, Jan. 15, 2016 – Many women who survive cancer have symptoms of chemotherapy-related nerve damage in their feet and hands years after treatment, a new study reveals. Moreover, this nerve damage – called chemotherapy-induced peripheral neuropathy – is associated with an increased risk of falls, the study found. "We can't dismiss neuropathy as a treatment side effect that goes away, because symptoms persist for years in nearly half of women," said lead author Kerri Winters-Stone, a research professor at Oregon Health and Science University in Portland. The study included 462 women who had survived cancer – including breast, lung, colon, ovarian or blood cancers. At an average of six years after cancer diagnosis, 45 percent of them still had symptoms of nerve damage, such as loss of feeling in their hands and feet. These symptoms were associated with much poorer physical ... Read more

Related support groups: Cancer, Peripheral Neuropathy

Uncontrolled Diabetes May Boost Dementia Risk

Posted 9 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – Diabetes patients with high rates of complications from the disease may face increased risk for dementia, a new study suggests. "We found that as diabetes progresses and an individual experiences more complications from the disease, the risk of dementia rises as well," wrote Dr. Wei-Che Chiu, of the National Taiwan University College of Public Health, in Taipei. Better blood sugar control can help prevent the mental decline associated with diabetes, he and his colleagues said. They examined data from more than 431,000 people in Taiwan who were older than 50 and newly diagnosed with diabetes. Complications of diabetes include vision loss, kidney failure and nerve damage. Over 12 years of follow-up, more than 6 percent of the patients were diagnosed with dementia. Those with a greater number of diabetes complications were at higher risk for mental decline than ... Read more

Related support groups: Diabetes, Type 2, Peripheral Neuropathy, Dementia, Diabetes, Type 1, Diabetic Neuropathy, Alzheimer's Disease, Diabetic Nerve Damage, Pre-Diabetes, Diabetic Kidney Disease, Mild Cognitive Impairment, Diabetes Mellitus, Diabetic Nephropathy, Arteriosclerotic Dementia, Diabetic Retinopathy, Lewy Body Dementia, Abnormal Glucose Tolerance, Retinopathy Prophylaxis

'Skinny Jeans' Linked to Woman's Nerve Damage

Posted 22 Jun 2015 by Drugs.com

MONDAY, June 22, 2015 – Long periods of squatting in tight jeans can cause muscle and nerve damage, a new case study suggests. The research involved a 35-year-old woman who arrived at a hospital complaining of severe weakness in both her ankles. The day before, she had helped a relative move and spent many hours squatting while emptying cupboards. She said she was wearing tight "skinny" jeans that became increasingly uncomfortable as the day progressed. That evening, she developed numbness in her feet and had difficulty walking. She tripped and fell, and spent several hours on the ground before she was found. When she arrived at the hospital, her calves were so swollen that her jeans had to be cut off, the researchers said. She had lost feeling in her lower legs and feet, and could not move her ankles or toes properly. Doctors determined she had a condition called compartment syndrome. ... Read more

Related support groups: Muscle Pain, Peripheral Neuropathy, Small Fiber Neuropathy

Health Tip: If You Have Peripheral Neuropathy

Posted 9 Jun 2015 by Drugs.com

-- Peripheral neuropathy, common among people with diabetes, is characterized by nerve damage in the fingers and toes. The American Podiatric Medical Association says people with peripheral neuropathy should: Regularly inspect the feet for wounds and signs of infection, since feeling to the feet may be reduced. Ask someone else to inspect the feet if unable to do so. Seek immediate care for any foot injury. Don't walk barefoot. Always wear sturdy, well-fitted shoes. Keep blood sugar under control and follow a diabetes treatment plan. Read more

Related support groups: Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Nerve Damage, Foot Care

Vegan Diet Might Ease Diabetic Nerve Pain

Posted 27 May 2015 by Drugs.com

WEDNESDAY, May 27, 2015 – A vegan diet might help people with diabetes-related nerve damage shed weight and find some pain relief, a small pilot study suggests. Vegan diets are free of all animal products, including eggs and dairy. Instead, people get their protein, fat and all other nutrients from foods such as beans, nuts, whole grains, vegetables, fruit and plant-based oils. In the new study, researchers tested whether a vegan diet could help people with type 2 diabetes and painful nerve damage in their feet or hands. The investigators found that over 20 weeks, the 17 people they assigned to the diet lost an average of 15 pounds. At the same time, blood flow to their feet improved and their pain eased up. Experts said the findings, reported May 25 in the journal Nutrition & Diabetes, highlight the importance of healthy eating and weight loss for people with type 2 diabetes. But it's ... Read more

Related support groups: Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Nerve Damage

Study Links Celiac Disease to Nerve Damage

Posted 11 May 2015 by Drugs.com

MONDAY, May 11, 2015 – People with the digestive disorder celiac disease are at increased risk for nerve damage, a new study suggests. Swedish researchers looked at more than 28,000 people with celiac disease and a "control" group of more than 139,000 without the disorder. The researchers found that those with celiac disease were 2.5 times more likely to be diagnosed with nerve damage, medically known as neuropathy. However, the risk of nerve damage among the study patients was still low and the association seen in the study did not prove a cause-and-effect relationship. The study was published online May 11 in the journal JAMA Neurology. "We found an increased risk of neuropathy in patients with celiac disease that persists after celiac disease diagnosis," Dr. Jonas Ludvigsson, of the Karolinska Institute in Stockholm, and colleagues wrote. "Although absolute risks for neuropathy are ... Read more

Related support groups: Peripheral Neuropathy, Neuropathic Pain, Celiac Disease, Small Fiber Neuropathy

Antidepressant Cymbalta Might Ease Chemo-Linked Pain

Posted 4 Jun 2012 by Drugs.com

MONDAY, June 4 – Cancer patients on certain chemotherapies often experience a painful tingling in their extremities called peripheral neuropathy, and a new study suggests the antidepressant Cymbalta may be the first treatment to work against the condition. In the small study, 59 percent of patients who'd experienced peripheral neuropathy said that they gained relief after taking Cymbalta (duloxetine), compared to 39 percent who took a "dummy" pill. Taking Cymbalta daily "decreases chronic chemotherapy-induced neuropathy and pain severity in the majority of patients who take it and it improves function and quality of life," said study author Ellen Lavoie Smith, an assistant professor at the University of Michigan's School of Nursing. She said the drug is also "very well tolerated" by most patients. Smith spoke at a news briefing Sunday at the annual meeting of the American Society of ... Read more

Related support groups: Cymbalta, Cancer, Peripheral Neuropathy, Duloxetine, Taxol, Paclitaxel, Onxol

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