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Related terms: Nonalcoholic Steatohepatitis, Idiopathic Fatty Liver, Steatosis, Steatohepatitis, Fatty Liver, NASH, NAFLD

Obesity in Youth Tied to Higher Odds for Liver Cancer in Men

Posted 21 Mar 2017 by Drugs.com

TUESDAY, March 21, 2017 – Overweight and obese young men are at increased risk for serious liver disease or liver cancer later in life, and those with diabetes have an even higher risk, a new study warns. Efforts to reduce obesity, "should be implemented from an early age to reduce the future burden of severe liver disease on individuals and society," say Swedish researchers led by Hannes Hagstrom, of the Center for Digestive Diseases at Karolinska University Hospital in Stockholm. A liver specialist in the United States agreed. "This should be a wake-up call for young men to take their weight seriously and take steps to stay in shape to hopefully prevent liver disease, diabetes and liver cancer in the future," said Dr. David Bernstein, chief of hepatology at Northwell Health in Manhasset, NY. He explained that obesity is linked to the development of a condition called non-alcoholic ... Read more

Related support groups: Obesity, Cirrhosis, Nonalcoholic Fatty Liver Disease, Liver Cirrhosis, Liver and Pancreatic Disease, Benign Liver Tumor, Hepatic Tumor

U.S. Vaccine Guidelines for Flu, HPV Updated

Posted 7 Feb 2017 by Drugs.com

TUESDAY, Feb. 7, 2017 – Roll up your sleeves, America. A national advisory panel of the U.S. Centers for Disease Control and Prevention has released its 2017 advisory for recommended shots affecting adults. This year's advisory revises guidance on seasonal flu shots by eliminating nasal flu vaccines and modifying flu-shot advice for people with egg allergy. It also tweaks recommendations for vaccines against human papillomavirus (HPV), hepatitis B and meningococcal disease. Doctors use the annually updated vaccine schedule to ensure that patients receive the right vaccines for their age, medical condition and other risk factors. The entire list includes 13 vaccinations. "All adults need immunizations to help them prevent getting and spreading serious disease that could result in poor health, missed work, medical bills, and not being able to care for family," said the report's lead ... Read more

Related support groups: Obesity, HIV Infection, Nonalcoholic Fatty Liver Disease, Autoimmune Disorders, Liver Cirrhosis, Gardasil, Liver and Pancreatic Disease, Hepatitis B Adult Vaccine, Twinrix, Cervarix, Human Papillomavirus Vaccine, Hepatitis B Prevention, Human Papillomavirus Prophylaxis, Meningococcal Meningitis Prophylaxis, Tetanus Immune Globulin, Influenza Prophylaxis, HyperTET S/D, Vaccination and Prophlaxis, Engerix-B, Hepatitis B Prophylaxis

Even One High-Fat Meal Can Harm Your Liver, Study Finds

Posted 24 Jan 2017 by Drugs.com

TUESDAY, Jan. 24, 2017 – Eating a high-fat meal – say, a cheeseburger and fries or a pepperoni pizza – disrupts liver function, a new, small study reveals. Researchers found that the high levels of saturated fat found in such rich foods immediately alter the work of the liver, possibly setting the body up for serious disease down the line. "The effects mimic the abnormalities seen in people with severe metabolic disease," said study co-author Dr. Michael Roden, referring to conditions like fatty liver disease and cirrhosis. "Our findings paint the picture of the earliest changes in liver metabolism leading to fatty liver diseases and liver cirrhosis in the context of obesity and type 2 diabetes," said Roden. He's scientific director of the German Diabetes Center at Heinrich Heine University in Dusseldorf. How long these metabolic alterations last after people indulge in a rich meal ... Read more

Related support groups: Obesity, Diabetes, Type 2, Cirrhosis, Nonalcoholic Fatty Liver Disease, Liver Cirrhosis, Liver and Pancreatic Disease

Health Tip: Health Risks of Childhood Obesity

Posted 29 Sep 2016 by Drugs.com

-- Obesity among children can lead to numerous health problems now and for many years to come. The U.S. Centers for Disease Control and Prevention says obese children are at greater risk of developing: High blood pressure and high cholesterol. Type 2 diabetes, insulin resistance and impaired fasting glucose. Asthma, sleep apnea and other breathing problems. Pain and discomfort of the joints and musculoskeletal system. Gallstones, heartburn and fatty liver disease. Behavioral problems, depression, poor self-esteem, poor quality of life and poor school performance. More Information See The Shape Of Things To Come – 8 Reasons Why Obesity Needs To Be Tackled Now for more information. Read more

Related support groups: Pain, Depression, High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension, High Cholesterol, Indigestion, Sleep Apnea, Insulin Resistance, Nonalcoholic Fatty Liver Disease, Pre-Diabetes, Psychiatric Disorders, Obstructive Sleep Apnea/Hypopnea Syndrome, Gallstones, Diabetes Mellitus, Hypertensive Heart Disease, Executive Function Disorder

Sweetened Drinks May Damage Heart, Review Finds

Posted 28 Sep 2015 by Drugs.com

MONDAY, Sept. 28, 2015 – Soft drinks and other sugar-sweetened beverages can seriously damage heart health, a new review finds. The added sugar in sodas, fruit drinks, sweet teas and energy drinks affects the body in ways that increase risk of heart attack, heart disease and stroke, said review author Vasanti Malik, a nutrition research scientist at Harvard's T.H. Chan School of Public Health in Boston. Consuming one or two servings a day of sugar-sweetened beverages has been linked to a 35 percent greater risk of heart attack or fatal heart disease, a 16 percent increased risk of stroke and as much as a 26 percent increased risk of developing type 2 diabetes, the report concluded. "Reducing the consumption of these drinks, it's not going to solve the heart disease epidemic, but it's one step that can have a measurable impact," Malik said. "It's not the only thing that needs to be ... Read more

Related support groups: Heart Disease, Heart Attack, Glucose, Transient Ischemic Attack, Nonalcoholic Fatty Liver Disease, Myocardial Infarction, Ischemic Stroke - Prophylaxis, Cardiovascular Risk Reduction, Dextrose, Thromboembolic Stroke Prophylaxis, Ischemic Heart Disease, Myocardial Infarction - Prophylaxis, Insta-Glucose, Dex4, Dex4 Pouch Pack, Dex4 Raspberry, Dex4 Strawberries & Cream, Glutol, Trutol, TRUEplus

Weight Loss Fights Liver Condition, No Matter How It's Done

Posted 21 Aug 2015 by Drugs.com

FRIDAY, Aug. 21, 2015 – Weight loss can improve liver health of obese or overweight people, whether excess pounds are shed through lifestyle changes or weight-loss surgery, a pair of studies finds. Both studies involved people with nonalcoholic steatohepatitis (NASH), an aggressive disease characterized by fat in the liver. It affects 2 percent to 5 percent of Americans, and can lead to permanent liver damage, according to the study published in the August issue of the journal Gastroenterology. "While the underlying cause of NASH is unclear, we most commonly see this condition in patients who are middle-aged and overweight or obese," Dr. Giulio Marchesini, of the University of Bologna, Italy, and colleagues wrote in an editorial accompanying the studies. "These two large prospective cohort studies strengthen the evidence that, no matter how you lose weight, weight loss improves liver ... Read more

Related support groups: Obesity, Weight Loss, Nonalcoholic Fatty Liver Disease

New MRI Test May Help Diagnose Liver Condition in Kids

Posted 5 Feb 2015 by Drugs.com

THURSDAY, Feb. 5, 2015 – A new medical imaging technique can help doctors better detect non-alcoholic fatty liver disease in children, new research suggests. Five million to 8 million children in the United States have the condition, but most cases go undiagnosed, according to the University of California, San Diego researchers. Children with the disease have large droplets of fat in at least 5 percent of their liver cells. Obesity and diabetes are risk factors for non-alcoholic fatty liver disease, which can lead to hepatitis, liver scarring, cirrhosis and liver cancer. "Currently, diagnosis of [non-alcoholic fatty liver disease] requires a liver biopsy, which is not always available or performed. This leads to both misdiagnosis and missed diagnoses, hampering patient care and progress in clinical research," study first author Dr. Jeffrey Schwimmer said in a university news release. ... Read more

Related support groups: Nonalcoholic Fatty Liver Disease, Diagnosis and Investigation

Scarring May Raise Death Risk From Fatty Liver Disease

Posted 16 Apr 2013 by Drugs.com

TUESDAY, April 16 – Advanced fibrosis – or progressive scarring of the liver – is tied to higher death rates from a type of fatty liver disease found in people who drink little or no alcohol, according to a new study. This increased mortality is primarily due to heart-related causes, not nonalcoholic fatty liver disease alone, the researchers said. The study was published in the April issue of the journal Hepatology. "Our findings confirm that [nonalcoholic fatty liver disease] patients without advanced fibrosis do not have higher mortality risk," lead study investigator Dr. W. Kim Ray, of the Mayo Clinic in Rochester, Minn., said in a journal news release. "Careful monitoring of disease progression in patients with [nonalcoholic fatty liver disease] and fibrosis, along with interventions that reduce cardiovascular risk factors, are warranted." The study involved data on more than ... Read more

Related support groups: Nonalcoholic Fatty Liver Disease

Fatty Liver Disease Doesn't Affect Survival, Study Finds

Posted 28 Nov 2011 by Drugs.com

MONDAY, Nov. 28 – A condition called non-alcoholic fatty liver disease (NAFLD) does not increase the risk of death, according to a new study finding that surprised Johns Hopkins researchers. It's long been thought that NAFLD – a condition associated with obesity and heart disease – had a detrimental impact on health and longevity. But the new study concluded that NAFLD does not affect survival. "Physicians have considered fatty liver disease a really worrisome risk factor for cardiovascular disease," study leader Dr. Mariana Lazo, a postdoctoral fellow at the Johns Hopkins University School of Medicine's Welch Center for Prevention, Epidemiology, and Clinical Research, said in a Hopkins news release. "Our data analysis shows this doesn't appear to be the case. We were surprised to say the least because we expected to learn by how much non-alcoholic fatty liver disease increased the ... Read more

Related support groups: Nonalcoholic Fatty Liver Disease

Obesity Greater Risk for Fatty Liver Than Alcohol, Study Finds

Posted 2 Jun 2011 by Drugs.com

THURSDAY, June 2 – Obesity and insulin resistance constitute a greater risk for fatty liver disease than moderate alcohol consumption, according to a new study that found drinking modest amounts of red wine posed no greater risk for developing the condition. For their study, published online May 23 in Annals of Medicine, Swedish researchers instructed 44 people to either abstain from alcohol or drink one (women) or two (men) glasses of red wine a day for three months. At the beginning and end of the three months, the investigators collected blood samples and conducted MRIs to measure the fatty content of participants' livers. "It turned out that the amount of fat in the liver was linked with obesity and insulin resistance and was almost not at all affected by the red wine. Specifically, after three months, none of the wine drinkers had developed fatty liver or elevated liver ... Read more

Related support groups: Obesity, Insulin Resistance, Nonalcoholic Fatty Liver Disease

Vitamin E, Diabetes Drug May Not Ease Obesity-Linked Liver Trouble in Kids

Posted 27 Apr 2011 by Drugs.com

TUESDAY, April 26 – Neither vitamin E nor the diabetes medication metformin worked any better than a placebo in treating fatty liver disease in children, according to new research. Fatty liver disease is an increasingly common, yet not well-known, disorder that can lead to very serious complications, such as cirrhosis of the liver. In the United States, as many as 20 percent of adults and 5 percent of children have the disorder, which is strongly tied to obesity, according to the American College of Gastroenterology. It had been hoped that vitamin E or metformin might help kids battle fatty liver disease. But when the researchers compared the two treatments to placebo on their ability to improve the results of a blood test that measures liver health, they found no statistically significant difference. However, when the researchers compared the results of a liver biopsy done at the ... Read more

Related support groups: Metformin, Glucophage, Nonalcoholic Fatty Liver Disease, Vitamin E, Glucophage XR, Glumetza, Riomet, Fortamet, Aquasol E, Alpha E, Aquavite-E, E Pherol, Amino-Opti-E, Nutr-E-Sol, Centrum Singles-Vitamin E, Vita-Plus E Natural, E-400 Clear, Aqua-E

Aerobic Exercise May Curb Non-Alcoholic Fatty Liver Disease: Report

Posted 13 Apr 2011 by Drugs.com

WEDNESDAY, April 13 – Aerobic exercise may slow the progression of non-alcoholic fatty liver disease in obese people, finds a new study. This type of workout appears to benefit these patients by increasing their metabolism and easing the oxidative damage caused by the liver disease, said the Cleveland Clinic researchers. Their study included 15 obese people with non-alcoholic fatty liver disease who walked on a treadmill at 85 percent of their maximum heart rate for one hour a day for seven consecutive days. The exercise increased the participants' insulin sensitivity and improved the liver's polyunsaturated lipid index (PUI)-- believed to be a marker of liver health – by 84 percent. These improvements were linked to an increase in the hormone adiponectin, which plays a role in the body's response to insulin and has anti-inflammatory properties that help reduce the risk of heart ... Read more

Related support groups: Nonalcoholic Fatty Liver Disease

Vitamin E Helps Treat Common Liver Disease

Posted 29 Apr 2010 by Drugs.com

WEDNESDAY, April 28 – A new study has identified vitamin E as a treatment that can provide relief for many of the estimated 10 million Americans who have the most common chronic liver disease. "This clearly shows that vitamin E is effective for treatment of patients with nonalcoholic steatohepatitis who don't have active diabetes," said study author Dr. Arun J. Sanyal, chairman of the division of gastroenterology, hepatology and nutrition at Virginia Commonwealth University. A report on the trial is published in the April 28 online edition of the New England Journal of Medicine. A second drug tested in the trial, the diabetes medication pioglitazone (Actos), provided some relief but did not meet the benchmarks set in the study, Sanyal added. The trial did not test the two treatments head-to-head. Instead, each was tested against a placebo, an inactive substance. Those treatments were ... Read more

Related support groups: Nonalcoholic Fatty Liver Disease, Vitamin E, Aquasol E, Alpha E, Aquavite-E, E Pherol, Nutr-E-Sol, Amino-Opti-E, Vita-Plus E Natural, Centrum Singles-Vitamin E, E-400 Clear, TheraTears Nutrition, Aqua-E

Researchers Identify 2 Genes Linked to Fatty Liver Disease

Posted 24 Mar 2010 by Drugs.com

WEDNESDAY, March 24 – Researchers have identified two gene variants that increase the risk of both the most common chronic liver disease in the United States as well as type 2 diabetes. People who carry the variants of a gene for apolipoprotein C3 (APOC3), which produces an enzyme important in fat metabolism, have a higher incidence of nonalcoholic fatty liver disease and also insulin resistance, according to a report in the March 25 issue of the New England Journal of Medicine. The research group was led by Dr. Gerald I. Shulman, a professor of physiological chemistry, medicine and cellular and molecular physiology at Yale University. Identification of the gene variants "might make it possible to screen individuals to see if they have a higher risk of fatty liver disease," Shulman said. "It also can provide an ideal drug target to prevent development of fatty liver disease and insulin ... Read more

Related support groups: Nonalcoholic Fatty Liver Disease

High Fructose Corn Syrup Linked to Liver Scarring

Posted 20 Mar 2010 by Drugs.com

FRIDAY, March 19 – New research links consumption of high-fructose corn syrup, the extremely popular sweetener that shows up in food products from ketchup to jelly, to liver damage in people with non-alcoholic fatty liver disease. It's not clear if the sweetener directly causes liver scarring, also known as fibrosis, but those who consumed more of the sweetener appeared to have more liver scarring, according to the report released online in advance of publication in an upcoming print issue of the journal Hepatology. "We have identified an environmental risk factor that may contribute to the metabolic syndrome of insulin resistance and the complications of the metabolic syndrome, including liver injury," Dr. Manal Abdelmalek, associate professor of medicine in the division of gastroenterology/hepatology at Duke University Medical Center and leader of a team of scientists behind the new ... Read more

Related support groups: Nonalcoholic Fatty Liver Disease

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