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Melanoma - Metastatic News

Drug Combo, Opdivo and Yervoy, Fights Melanoma That Has Spread to Brain

Posted 23 Aug 2018 by Drugs.com

THURSDAY, Aug. 23, 2018 – A combination of two drugs that work with the immune system can help beat back melanoma that has moved to the brain, an early clinical trial has found. The study included 94 patients with advanced melanoma that had invaded the brain. All were treated with two "immunotherapy" drugs – Opdivo (nivolumab) and Yervoy (ipilimumab) – which help the immune system find and ...

Frequent Skin Cancers May Signal Risk of Other Cancers, Too

Posted 9 Aug 2018 by Drugs.com

THURSDAY, Aug. 9, 2018 – People who have frequent recurrences of a common skin cancer may be at increased risk of a range of other cancers, a new study suggests. Researchers found the heightened risk among patients who'd had many bouts of basal cell carcinoma (BCC) – a highly treatable form of skin cancer diagnosed in over 3 million Americans each year. Patients who'd developed at least six ...

The Dark Side of Sunless Tanning

Posted 3 Aug 2018 by Drugs.com

FRIDAY, Aug. 3, 2018 – Don't kid yourself that using a sunless tanning product will prevent skin cancer. Unless you're willing to stop sunbathing altogether, you're still at risk for skin damage, researchers report. "For the most part, adults who use sunless tanning products continue to engage in risky tanning behaviors," said study leader Matthew Mansh, a dermatology resident at the University ...

Gyms With Tanning Beds Send Mixed Message

Posted 27 Jul 2018 by Drugs.com

FRIDAY, July 27, 2018 – Gym rats are trying to get healthy. So why do so many U.S. gyms have tanning beds, researchers want to know. Since indoor tanning raises the risk of skin cancer, this common combo sends a conflicting message to gym users, University of Connecticut researchers say. "By pairing exercise with tanning beds, gyms send the message that tanning is part of a healthy lifestyle. It ...

Yes, Fingernail Cancer Is a Thing -- Just Ask This Beauty Queen

Posted 26 Jul 2018 by Drugs.com

THURSDAY, July 26, 2018 – Karolina Jasko was a high school senior when a nail salon worker pointed out the black vertical line on her right thumbnail. Because she typically painted her nails, the black line had gone unnoticed and unheeded, but then it started to show signs of infection. At that point, Jasko sought out medical advice and got her diagnosis: a melanoma of the nail. "My mom was ...

Immune-Based Therapy May Help When Melanoma Spreads to Brain

Posted 12 Jul 2018 by Drugs.com

THURSDAY, July 12, 2018 – A type of therapy that harnesses the immune system is giving new hope to people battling a once hopeless cancer – melanoma that's spread to the brain. New research involving more than 2,700 U.S. patients is confirming what specialists in the field have long known – that "checkpoint blockade" treatment can beat back these devastating tumors. "Physicians who treat ...

How to Use Sunscreens the Right Way

Posted 10 Jul 2018 by Drugs.com

TUESDAY, July 10, 2018 – Stick or spray-on sunscreens are essential tools against skin cancer, but it's important to use them the right way, a dermatologist says. "Sticks are easy for under the eyes and the backs of the hands, while spray sunscreens are often easier to apply on children," Dr. Debra Wattenberg said in an American Academy of Dermatology news release. "However, it's important to ...

With Summer Here, Check for Signs of Skin Cancer

Posted 1 Jul 2018 by Drugs.com

SATURDAY, June 30, 2018 – During the summer when people trade in their jackets and jeans for flip flops and bathing suits, more skin is exposed to the sun's harmful UV rays. Dr. Katherine Gordon, assistant professor of dermatology at UT Southwestern Medical Center in Dallas, said summer is the perfect time for people to get in the habit of checking their skin for signs of cancer. "We recommend ...

FDA Approves Mektovi (binimetinib) and Braftovi (encorafenib) in Combination for Unresectable or Metastatic Melanoma with BRAF Mutations

Posted 30 Jun 2018 by Drugs.com

On June 27, 2018, the Food and Drug Administration approved encorafenib and binimetinib (Braftovi and Mektovi, Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test. Approval was based on a randomized, active-controlled, open-label, multicenter trial (COLUMBUS; NCT01909453) in 577 ...

Array BioPharma Announces FDA Approval of Braftovi (encorafenib) in Combination with Mektovi (binimetinib) for Unresectable or Metastatic Melanoma with BRAF Mutations

Posted 30 Jun 2018 by Drugs.com

BOULDER, Colo., June 27, 2018 /PRNewswire/ – Array BioPharma Inc. (Nasdaq: ARRY) today announced that the U.S. Food and Drug Administration (FDA) has approved Braftovi capsules in combination with Mektovi tablets for the treatment of patients with unresectable or metastatic melanoma with a BRAFV600E or BRAFV600K mutation, as detected by an FDA-approved test. Braftovi is not indicated for the ...

AI Better Than Docs at Catching Skin Cancers

Posted 31 May 2018 by Drugs.com

THURSDAY, May 31, 2018 – A computer can beat even highly experienced dermatologists in spotting deadly melanomas, researchers report. The study is the latest to test the idea that "artificial intelligence" can improve medical diagnoses. Typically, it works like this: Researchers develop an algorithm using "deep learning" – where the computer system essentially mimics the brain's neural ...

How to Do a Self-Check for Skin Cancer

Posted 27 May 2018 by Drugs.com

SATURDAY, May 26, 2018 – Learning how to do a skin self-exam could save your life. "Skin cancer is one of the few cancers you can see with the naked eye," said Dr. Ali Hendi, an assistant clinical professor of dermatology at Georgetown University Medical Center in Washington, D.C. "Yet sadly, many people don't know how to be their own hero when it comes to skin cancer, including what to look for ...

Another Foe for the U.S. Military: Skin Cancer

Posted 24 May 2018 by Drugs.com

THURSDAY, May 24, 2018 – For U.S. military personnel, deployment carries many dangers. And besides the well-known threats they face, these men and women are also at a higher-than-average risk for skin cancer, including potentially deadly melanoma, a new research review suggests. Two military groups face a particularly high risk: white service members and men over 50, according to the report. ...

Men May Gain More From Cancer Immunotherapy

Posted 17 May 2018 by Drugs.com

THURSDAY, May 17, 2018 – Male cancer patients seem to fare significantly better following immunotherapy treatment than female patients, new research indicates. "Both sex and gender can potentially affect the strength of the body's immune response," explained study author Dr. Fabio Conforti, from the European Institute of Oncology in Milan, Italy. For example, Conforti noted that women generally ...

Outdoor Job? Skin Cancer Can Take a Hefty Toll

Posted 27 Apr 2018 by Drugs.com

FRIDAY, April 27, 2018 – Construction workers, farmers and others who work in the sun are at greater risk for skin cancer, according to researchers. And a new study reveals these job-related cancers cost nations millions in medical expenses. The researchers said lawmakers should address this trend and take steps to reduce job-related exposure to the sun's harmful ultraviolet rays. "The findings ...

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isotretinoin, Keytruda, Opdivo, nivolumab, Yervoy, Zelboraf, pembrolizumab, vemurafenib, Mekinist, view more... Mektovi, encorafenib, Braftovi, binimetinib, cobimetinib, dacarbazine, Proleukin, DTIC-Dome, PegIntron, talimogene laherparepvec, Sylatron, trametinib, Tafinlar, dabrafenib, ipilimumab, temozolomide, Imlygic, Cotellic, peginterferon alfa-2b, aldesleukin