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Intraabdominal Infection News

The 7 Deadliest Emergency General Surgeries

Posted 27 Apr 2016 by Drugs.com

WEDNESDAY, April 27, 2016 – Seven types of operations, including appendectomy and gall bladder removal, account for four out of five emergency general-surgery deaths in the United States, a new study reports. The procedures are: partial removal of the large or small intestine; surgery to repair a bleeding or torn ulcer; separating abdominal organs that have adhered to each other; appendix removal; gall bladder removal; and open-abdominal surgery. Researchers found these operations also account for 80 percent of complications from emergency general surgery, a specialty that focuses primarily on abdominal health problems. "Our gastrointestinal tract is just so specialized and so critical to our existence. We think it's easy to operate on, but then in practice it's very difficult for patients," said senior author Dr. Joaquim Havens, an instructor in trauma and emergency surgery at Brigham ... Read more

Related support groups: Stomach Ulcer, Gastric Ulcer, Peptic Ulcer, Intestinal Obstruction, Appendicitis, Intraabdominal Infection, Appendectomy

Routine Screening for Child Abuse Might Spot More Cases: Study

Posted 5 Oct 2015 by Drugs.com

MONDAY, Oct. 5, 2015 – The early signs of child abuse among infants and toddlers – head trauma, cracked ribs or abdominal injuries – are often missed, and that may be due in part to a lack of standardized screening, researchers report. "We probably need to increase testing for abusive injuries, but these data are less about an increase or decrease and more about consistency," said study author Dr. Daniel Lindberg, from the Kempe Center for the Prevention and Treatment of Child Abuse and Neglect in Denver. "If your child has a femur fracture, the decision to test for other abusive injuries shouldn't depend on the hospital you go to, or the color of your skin, or your net worth or your demeanor," Lindberg said. "This study suggests that young kids who present with the most concerning sentinel injuries should at least prompt the provider to consider whether abuse is likely and, as ... Read more

Related support groups: Head Injury, Fracture, bone, Intraabdominal Infection

FDA Medwatch Alert: Zerbaxa (ceftolozane and tazobactam): Drug Safety Communication - FDA Cautions about Dose Confusion and Medication Errors

Posted 20 May 2015 by Drugs.com

ISSUE: The U.S. Food and Drug Administration (FDA) is warning health care professionals about the risk for dosing errors with the antibacterial drug Zerbaxa (ceftolozane and tazobactam) due to confusion about the drug strength displayed on the vialand carton labeling. (See the Drug Safety Communication for Label Photos). FDA evaluated seven reported cases of medication error that occurred during preparation of the dose in the pharmacy due to confusion with the display of the strength of individual ingredients on Zerbaxa’s vial labels and carton labeling. Listing the individual drug strengths led to confusion because it was different from labeling for other drugs in the beta-lactam/beta-lactamase class that express strength as the sum of the two active ingredients. In some cases, this led to administration of 50% more drug than was prescribed. No adverse events were reported among these s ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection, Ceftolozane/tazobactam, Zerbaxa

New Antibiotic Avycaz Approved

Posted 26 Feb 2015 by Drugs.com

THURSDAY, Feb. 26, 2015 – The combination antibiotic Avycaz (ceftazidime-avibactam) has been approved by the U.S. Food and Drug Administration to treat adults with complicated infections of the intra-abdominal area or urinary tract, including the kidneys. Avycaz contains the previously approved antibiotic ceftazidime, and the newer antibacterial drug avibactam, the agency said in a news release. Approved to help combat antibacterial resistance, Avycaz is sanctioned for people who have limited or no other treatment options, the FDA said. The most common side effects identified during clinical testing included vomiting, nausea, constipation and anxiety. Users with poor kidney function had more serious adverse reactions including decreased effectiveness and seizures, the agency said. And users allergic to penicillin may be at greater risk of serious skin reactions and anaphylaxis, the FDA ... Read more

Related support groups: Urinary Tract Infection, Kidney Infections, Intraabdominal Infection, Pyelonephritis

FDA Approves Avycaz (ceftazidime and avibactam) for Complicated Abdominal and Urinary Tract Infections

Posted 25 Feb 2015 by Drugs.com

February 25, 2015 – The U.S. Food and Drug Administration today approved Avycaz (ceftazidime-avibactam), a new antibacterial drug product, to treat adults with complicated intra-abdominal infections (cIAI), in combination with metronidazole, and complicated urinary tract infections (cUTI), including kidney infections (pyelonephritis), who have limited or no alternative treatment options. Avycaz contains two drugs: ceftazidime, a previously approved cephalosporin antibacterial drug, and avibactam, to help extend bacterial resistance. “The FDA is committed to making therapies available to treat patients with unmet medical need,” said Edward Cox, M.D., M.P.H, director of the Office of Antimicrobial Products in the FDA’s Center for Drug Evaluation and Research. “It is important that the use of Avycaz be reserved to situations when there are limited or no alternative antibacterial drugs fo ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

Combination Antibiotic Zerbaxa Approved

Posted 22 Dec 2014 by Drugs.com

MONDAY, Dec. 22, 2014 – The combination antibiotic Zerbaxa (ceftolozane/tazobactam) has been approved by the U.S. Food and Drug Administration to treat adults with complicated abdominal infections and complicated urinary tract infections. The approval for abdominal infections was approved in combination with another drug, metronidazole, the agency said in news release. The approval for urinary tract infection includes infection of the kidney. Zerbaxa is the fourth antibiotic to be FDA-approved in 2014, following approval of Dalvance (dalbavancin), Sivextro (tedizolid) and Orbactiv (oritavancin). The drug's label includes a warning about decreased effectiveness among people with kidney impairment, the FDA said. The most common side effects reported during clinical testing included nausea, diarrhea, headache and fever. Zerbaxa is marketed by Cubist Pharmaceuticals, based in Lexington, ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

FDA Approves Zerbaxa (ceftolozane/tazobactam) for Complicated Intra-Abdominal/Urinary Tract Infections

Posted 19 Dec 2014 by Drugs.com

December 19, 2014 – The U.S. Food and Drug Administration today approved Zerbaxa (ceftolozane/tazobactam), a new antibacterial drug product, to treat adults with complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI). Zerbaxa is a combination product containing ceftolozane, a cephalosporin antibacterial drug, and tazobactam, a beta-lactamase inhibitor. Zerbaxa is used to treat cUTI, including kidney infection (pyelonephritis). It is used in combination with metronidazole to treat cIAI. Zerbaxa is the fourth new antibacterial drug approved by the FDA this year. The agency approved Dalvance (dalbavancin) in May, Sivextro (tedizolid) in June and Orbactiv (oritavancin) in August. “The FDA approval of several new antibacterial drugs this year demonstrates the agency’s commitment to increasing the availability of treatment options for patients and phy ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

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metronidazole, clindamycin, Cipro, ciprofloxacin, Flagyl, Avelox, Rocephin, ampicillin, Cleocin, view more... gentamicin, tobramycin, Metro, ceftriaxone, amikacin, moxifloxacin, Flagyl IV, cefotaxime, ertapenem, cefepime, Cleocin HCl, Zosyn, meropenem, Unasyn, Garamycin, Invanz, Cleocin Pediatric, Tobi, Amikin, Merrem, cilastatin / imipenem, Primaxin IM, Cipro XR, piperacillin, ceftazidime, Tygacil, Amikin Pediatric, cefoperazone, Cleocin Phosphate, Nebcin, Cipro IV, cefoxitin, Timentin, Fortaz, tigecycline, Cefizox, Nebcin Pediatric, ceftolozane / tazobactam, Flagyl 375, avibactam / ceftazidime, Cidomycin, Septopal, cefotetan, Metro IV, Pipracil, doripenem, Doribax, Cefobid, Zerbaxa, Avycaz, Avelox IV, Trovan, Tazicef Novaplus, Metryl, Merrem Novaplus, Protostat, Totacillin-N, Mefoxin, ceftizoxime, Cefotan, Claforan, Tazicef, clavulanate / ticarcillin, ticarcillin, aztreonam, ampicillin / sulbactam, Ticar, trovafloxacin, Omnipen-N, piperacillin / tazobactam, Ceptaz, Omnipen, Primaxin IV, Maxipime, Azactam, Principen, Tazidime