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Inflammatory Bowel Disease News

Related terms: IBD

Inflammatory Bowel Disease May Raise Cancer Risk in Kids

Posted 21 Sep 2017 by Drugs.com

THURSDAY, Sept. 21, 2017 – Children with inflammatory bowel disease (IBD) face an increased risk of cancer, a new study claims. The risk persists into adulthood, and is especially elevated for gastrointestinal cancers, the researchers added. The "extent and duration of chronic inflammation might be the main driving mechanisms underlying the increased risk of cancer," the researchers suggested. The international team, led by Dr. Ola Olen, a pediatric gastroenterologist at Karolinska Institute in Stockholm, compared about 9,400 patients in Sweden who were diagnosed with IBD before age 18 to a control group of nearly 93,000 people without IBD. The risk of cancer up to an average age of 30 was 3.3 cases per 1,000 person years among those with IBD. That compared with 1.5 cases per 1,000 person years in the control group. So, the overall risk of cancer among people with IBD is still low, the ... Read more

Related support groups: Cancer, Crohn's Disease, Colitis, Ulcerative Colitis, Crohn's Disease - Maintenance, Colorectal Cancer, Inflammatory Bowel Disease, Ulcerative Colitis - Active, Crohn's Disease - Acute, Ulcerative Colitis - Maintenance, Lymphocytic Colitis, Pseudomembranous Colitis, Allergic Colitis, Noninfectious Colitis, Enterocolitis

Country Kids Less Likely to Develop Bowel Disease Than Their City Cousins

Posted 31 Jul 2017 by Drugs.com

MONDAY, July 31, 2017 – People in rural areas may be less likely to develop inflammatory bowel disease (IBD) than those in cities, Canadian researchers report. "Our findings show that children, particularly those under the age of 10, experience a protective effect against IBD if they live in a rural household," said study author Dr. Eric Benchimol. "This effect is particularly strong in children who are raised in a rural household in the first five years of life," said Benchimol, a pediatric gastroenterologist at Children's Hospital of Eastern Ontario in Ottawa. These are important findings, Benchimol said in a hospital news release, noting their previous work shows the number of very young children diagnosed with IBD has jumped in the past 20 years. IBD – which includes Crohn's disease and ulcerative colitis – is a lifelong condition that causes inflammation in the digestive tract, ... Read more

Related support groups: Crohn's Disease, Crohn's Disease - Maintenance, Inflammatory Bowel Disease, Crohn's Disease - Acute, Ulcerative Proctitis

Scientists Spot Genes Behind Crohn's, Ulcerative Colitis

Posted 29 Jun 2017 by Drugs.com

THURSDAY, June 29, 2017 – Researchers say they've come closer to pinpointing genes linked with inflammatory bowel diseases such as Crohn's and ulcerative colitis. For the study, the investigators examined the genomes of nearly 68,000 people. Of the regions of the genome associated with inflammatory bowel disease (IBD), 18 could be traced to a single genetic variant with more than 95 percent certainty. "We have taken the biggest ever data set for IBD and applied careful statistics to narrow down to the individual genetic variants involved," said study co-author Dr. Jeffrey Barrett, from the Wellcome Trust Sanger Institute in the United Kingdom. "Now we have a clearer picture of which genes do and do not play a role in the disease. We are zooming in on the genetic culprits of IBD," he said in an institute news release. The findings could lead to improved effectiveness of current ... Read more

Related support groups: Prednisone, Methylprednisolone, Crohn's Disease, Ulcerative Colitis, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Crohn's Disease - Maintenance, Betamethasone, Budesonide, Inflammatory Bowel Disease, Ulcerative Colitis - Active, Entocort, Crohn's Disease - Acute, Decadron, Solu-Medrol, Ulcerative Colitis - Maintenance

New Meds Make Inroads Against Crohn's Disease

Posted 13 Apr 2017 by Drugs.com

THURSDAY, April 13, 2017 – Fewer Americans with Crohn's disease are ending up in the hospital than in the past, according to a new federal study. Crohn's is a chronic inflammatory bowel disorder that often leads to surgery for most with the disease. Hospitalization rates for Crohn's disease remained stable in the United States between 2003 and 2013. That's a change from a study done from 1998 to 2004 that saw more than 4 percent increases in Crohn's hospitalizations each year, researchers with the U.S. Centers for Disease Control and Prevention said. The stable hospital rates are likely due to the 1998 introduction of a new class of biologic drugs. Examples of these medications used to treat Crohn's disease include: adalimumab (Humira), infliximab (Remicade), certolizumab (Cimzia) and ustekinumab (Stelara), according to the U.S. National Institute of Diabetes and Digestive and Kidney ... Read more

Related support groups: Humira, Crohn's Disease, Remicade, Ulcerative Colitis, Crohn's Disease - Maintenance, Inflammatory Bowel Disease, Stelara, Ulcerative Colitis - Active, Crohn's Disease - Acute, Cimzia, Ulcerative Colitis - Maintenance, Adalimumab, Infliximab, Inflectra, Certolizumab, Ustekinumab, Amjevita

Family History of Colon Cancer Calls for Earlier Screening

Posted 21 Mar 2017 by Drugs.com

TUESDAY, March 21, 2017 – If you've got a family history of colon or rectal cancers, you probably need to start screening for these conditions before you turn 50, a cancer expert says. People with a close relative who has had colon or rectal cancer have a greater risk of being diagnosed with these cancers too, said Dr. Walter Koltun, chief of colon and rectal surgery at the Penn State Health Hershey Medical Center in a hospital news release. "A significant portion of the population does have those risk factors," Koltun said. "And their risk goes up significantly depending on who has been affected." If more than one close relative has had colon or rectal cancer, your risk of getting such a cancer is 12 times greater, he added. People who are diagnosed with colon or rectal cancers at a young age are more likely to have a genetic trait that could increase their risk for the disease. ... Read more

Related support groups: Cancer, Breast Cancer, Crohn's Disease, Colonoscopy, Prostate Cancer, Colorectal Cancer, Inflammatory Bowel Disease, History - Radiation Therapy

Common Virus May Be Linked to Heart Disease, Diabetes in Some Women

Posted 23 Feb 2017 by Drugs.com

THURSDAY, Feb. 23, 2017 – A common virus may make some women more susceptible to both heart disease and type 2 diabetes, a new study suggests. Scientists at the University of California, San Francisco found normal-weight women under age 50 who were infected with cytomegalovirus (CMV) were more likely to have metabolic syndrome than their peers. Metabolic syndrome is a collection of risk factors for heart disease and diabetes that includes excess belly fat, unhealthy cholesterol levels, high blood pressure and high blood sugar levels. CMV, a herpes virus, is believed to infect roughly half of the U.S. population over the age of 40. Typically there are no symptoms unless the person's immune system is weakened. Ironically, obese women infected with CMV were less likely to have metabolic syndrome than obese women not infected with the virus, the researchers found. However, obese women were ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, High Cholesterol, Crohn's Disease, Insulin Resistance, Crohn's Disease - Maintenance, Pre-Diabetes, Inflammatory Bowel Disease, Crohn's Disease - Acute, Viral Infection, Cytomegalovirus (CMV) Infection, Ulcerative Proctitis, Ischemic Heart Disease, CMV Pneumonia, CMV Retinitis, CMV Gastroenteritis

Special Diet May Be Boon for Kids With Crohn's, Colitis

Posted 10 Jan 2017 by Drugs.com

MONDAY, Jan. 9, 2017 – Children with Crohn's disease and ulcerative colitis may be able to achieve relief without medications by eating a special diet, a small study suggests. The diet includes non-processed foods, such as fruits, vegetables, meats and nuts. Over 12 weeks, the diet appeared to ease all signs of these inflammatory bowel diseases in eight of the 10 affected children, researchers report. "The study shows that without other intervention, other changes, we can improve individuals' clinical as well as laboratory markers," said study author Dr. David Suskind. He's a professor of pediatrics and director of clinical gastroenterology at Seattle Children's Hospital. "I'm not surprised," Suskind added, "primarily because preliminary studies ... opened our eyes to the idea that diet had an impact." Inflammatory bowel disease (IBD) affects about 1.6 million Americans, according to ... Read more

Related support groups: Crohn's Disease, Colitis, Ulcerative Colitis, Dietary Supplementation, Crohn's Disease - Maintenance, Asacol, Creon, Sulfasalazine, Pentasa, Inflammatory Bowel Disease, Ulcerative Colitis - Active, Lialda, Crohn's Disease - Acute, Ulcerative Colitis - Maintenance, Apriso, Lactaid, Mesalamine, Canasa, Zenpep, Pancrease

The Scoop About Healthy Poop

Posted 25 Oct 2016 by Drugs.com

TUESDAY, Oct. 25, 2016 – Your bowel movements can offer important clues about your health, a doctor says. If bowel movements feel comfortable, then it's likely all is well, said Dr. Gabriel Neal, a family medicine doctor and clinical assistant professor at Texas A&M College of Medicine. "Normal bowel movements are relatively soft but dense. They should be any shade of brown or green," Neal said in a college news release. Viruses and bacteria in the intestinal tract can cause stool discoloration, diarrhea or blood in the stool. The color of the blood can help your doctor pinpoint the location of the infection. "If an infection is in the lower intestines or colon, then the blood in your stool is going to be red. If you find black blood, then the blood has oxidized and is from higher up in your digestive tract, such as the stomach or upper intestines," Neal said. People with gallbladder ... Read more

Related support groups: Diarrhea, Constipation, Crohn's Disease, Constipation - Chronic, Gastrointestinal Disorders, Inflammatory Bowel Disease, Gallbladder Disease, Constipation - Acute, Diarrhea, Chronic, Diarrhea, Acute, Infectious Diarrhea

Study Identifies Genetic Subtypes of Crohn's Disease

Posted 14 Oct 2016 by Drugs.com

FRIDAY, Oct. 14, 2016 – Crohn's disease appears to have at least two distinct genetic subtypes, which could explain why the condition is so hard to treat, a new study suggests. "The one-treatment-fits-all approach doesn't seem to be working for Crohn's patients," said study co-senior author Dr. Shehzad Sheikh. He's an assistant professor in the departments of medicine and genetics at the University of North Carolina School of Medicine. "It's plausible that this is because only a subset of patients has the type of disease that responds to standard therapy, whereas, for the rest of the patients, we're really not hitting the right targets," Sheikh said in a university news release. Crohn's is a chronic inflammatory disorder of the intestinal tract. The most common symptoms are diarrhea, stomach cramps and weight loss. The course and severity of the disease vary widely from patient to ... Read more

Related support groups: Humira, Crohn's Disease, Crohn's Disease - Maintenance, Asacol, Sulfasalazine, Stelara, Inflammatory Bowel Disease, Pentasa, Lialda, Crohn's Disease - Acute, Apriso, Canasa, Mesalamine, Delzicol, Asacol HD, Azulfidine, Diagnosis and Investigation, Sulfazine, Rowasa, Salofalk

Generic Biologic Drugs Seem as Effective as Originals

Posted 1 Aug 2016 by Drugs.com

MONDAY, Aug. 1, 2016 – Generic biologic drugs are similarly effective to brand-name counterparts in treating rheumatoid arthritis, inflammatory bowel disease and psoriasis, a new study says. Biologics are medications made from living cells. They are complicated to manufacturer and companies that make brand-name versions say cheaper generic versions aren't interchangeable with their products. The patents of many brand-name biologics are expiring and the use of generic versions (called biosimilars) could save patients and the healthcare system significant amounts of money, the Johns Hopkins University researchers noted. "The billion-dollar question has been whether these 'generic biologics' are the same as the brand-name versions," study leader Dr. G. Caleb Alexander, said in a university news release. "The same debate occurred with the advent of less complicated generic drugs and now ... Read more

Related support groups: Rheumatoid Arthritis, Psoriasis, Inflammatory Bowel Disease

Ultrasound Might Speed Up Digestive Drug Delivery: Animal Study

Posted 21 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 21, 2015 – Ultrasound waves could be used to rapidly deliver drugs to the digestive system, new animal research suggests. This new approach to drug delivery might potentially benefit people with inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. However, this new method of drug delivery hasn't yet been tested in humans. "With additional research, our technology could prove invaluable in both clinical and research settings, enabling improved therapies and expansion of research techniques applied to the [gastrointestinal] tract," said co-senior study author Daniel Blankschtein, a professor of chemical engineering at Massachusetts Institute of Technology (MIT) in Cambridge. "[Our study] demonstrates for the first time the active administration of drugs, including biologics, through the GI tract," he said in an MIT news release. The ... Read more

Related support groups: Crohn's Disease, Colitis, Ulcerative Colitis, Crohn's Disease - Maintenance, Inflammatory Bowel Disease, Ulcerative Colitis - Active, Crohn's Disease - Acute, Ulcerative Colitis - Maintenance, Diagnosis and Investigation

Making Headway Toward Causes of Eczema

Posted 19 Oct 2015 by Drugs.com

MONDAY, Oct. 19, 2015 – New gene variants associated with the skin condition eczema have been identified by an international team of researchers. Eczema, characterized by itchy, red rashes, is known to run in families. The new findings add to the number of genetic variants known to increase risk for the condition, making the total 31. The researchers did this by analyzing the genomes (genetic makeup) of 377,000 people worldwide. "Though the genetic variants identified in this current study represent only a small proportion of the risk for developing eczema ... they do give new insights into important disease mechanisms," said study leader Lavinia Paternoster, an epidemiologist at the University of Bristol in England. "Through ongoing research in this area, these findings could be turned into treatments of the future," she said in a university news release. All of the newly identified ... Read more

Related support groups: Skin Rash, Eczema, Inflammatory Bowel Disease, Minor Skin Conditions

More Evidence High-Fiber, Mediterranean Diet Is Good for You

Posted 29 Sep 2015 by Drugs.com

TUESDAY, Sept. 29, 2015 – Numerous studies have extolled the health benefits of the Mediterranean diet. Now, research suggests the regimen may also boost levels of beneficial fatty acids. These so-called "short chain fatty acids" are produced by bacteria in the intestine during fermentation of insoluble fiber from fruits, vegetables and legumes. The fatty acids are believed to provide a number of health benefits, including a lower risk of diabetes, heart disease and inflammatory diseases, an Italian team reports in the Sept. 29 issue of the journal Gut. "We provide here tangible evidence of the impact of a healthy diet and a Mediterranean dietary pattern," wrote the team led by Danilo Ercolini, a professor of microbiology at the University of Naples in Italy. The study of 153 Italian adults found higher levels of short chain fatty acids in vegans, vegetarians and those who closely ... Read more

Related support groups: Diabetes, Type 2, Heart Disease, Crohn's Disease, Ulcerative Colitis, Fish Oil, Lovaza, Inflammatory Bowel Disease, Omega-3, Dietary Fiber Supplementation, Omega 3-6-9 Complex, EPA Fish Oil, Omega-3 Polyunsaturated Fatty Acids, Restora, Omacor, Animi-3, Sea-Omega 30, Marine Lipid Concentrate, Super-EPA, Mi-Omega, MegaKrill

Health Tip: Should I Talk to my Doctor About Gas?

Posted 10 Aug 2015 by Drugs.com

-- While everyone has intestinal gas, some people have severe bloating that causes discomfort and other problems. The Mayo Clinic mentions these warning signs that you may need to see a doctor: Intestinal gas that is persistent and severe. Intestinal gas that occurs with vomiting. Long-term diarrhea, bloody stool or constipation. Weight loss for no apparent reason. Heartburn. Read more

Related support groups: GERD, Diarrhea, Constipation, Weight Loss, Gas, Abdominal Distension, Colitis, Constipation - Chronic, Indigestion, Hemorrhoids, Gastrointestinal Disorders, Inflammatory Bowel Disease, Duodenitis/Gastritis, Constipation - Acute, Diarrhea, Chronic, Anal Fissure and Fistula, Diarrhea, Acute, Infectious Diarrhea, Functional Gastric Disorder, Acute Abdomen

Severe Burns May Trigger Dangerous Shifts in Gut Germs

Posted 8 Jul 2015 by Drugs.com

WEDNESDAY, July 8, 2015 – People who suffer severe burns may experience potentially dangerous changes in the 100 trillion bacteria inside their gastrointestinal (GI) tract, a small study suggests. At issue is the breakdown of good and bad bacteria typically found inside a healthy person's GI tract. Researchers from the health sciences division of Loyola University Chicago in Maywood, Ill., observed that after a severe burn, four patients experienced a big increase in the number of potentially harmful bacteria and a corresponding drop in relatively beneficial bacteria. The potentially harmful bacteria are part of a family that includes E. coli and salmonella. Such an imbalance, known as "dysbiosis," has been linked to many conditions, including inflammatory bowel disease, obesity, rheumatoid arthritis and diabetes, study lead author Dr. Mashkoor Choudhry, a professor of surgical ... Read more

Related support groups: Obesity, Diabetes, Type 2, Rheumatoid Arthritis, Gastrointestinal Disorders, Inflammatory Bowel Disease, Burns - External, Burns, Nitrogen Retention

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