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Statins Help Healthy People Lower Their 'Bad' Cholesterol

Posted 7 Sep 2017 by Drugs.com

THURSDAY, Sept. 7, 2017 – Cholesterol-lowering statins reduce the risk of heart disease and death in otherwise healthy people who have very high levels of "bad" LDL cholesterol, a long-term study finds. For 20 years, more than 5,500 men in Scotland who did not have heart disease but who had high levels of LDL took 40 milligrams of pravastatin, a relatively weak type of statin, daily. Doing so reduced their overall risk of death by 18 percent, the risk of death from heart disease by 28 percent, and the risk of death from other cardiovascular diseases by 25 percent. "For the first time, we show that statins reduce the risk of death in this specific group of people who appear largely healthy, except for very high LDL levels," said study senior author Dr. Kausik Ray, a professor in the School of Public Health at Imperial College London. The findings challenge taking a "watch-and-wait" ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Rosuvastatin, Red Yeast Rice, Prevention of Cardiovascular Disease, Pravachol, Livalo, Cardiovascular Risk Reduction, Hyperlipoproteinemia Type IIa (Elevated LDL), Lescol, Lescol XL, Mevacor, Pitavastatin, Baycol

Is the 'Anti-Statin' Trend Threatening Lives?

Posted 25 Jul 2017 by Drugs.com

MONDAY, July 24, 2017 – A wave of anti-science skepticism may put people with high cholesterol at risk if they're convinced to quit life-saving statin medications, heart experts warn. An "internet-driven cult" is attacking the safety and effectiveness of cholesterol-lowering statins, despite mounds of clinical trial data showing the drugs work and produce minimal side effects, said Dr. Steven Nissen, chairman of cardiovascular medicine at the Cleveland Clinic. "Unfortunately, we're in an era now where, with the internet, people with fringe views like this can gain the upper hand," Nissen said. "They've been very aggressive promoting to the public the idea that these drugs that are responsible for saving millions of lives are somehow bad for you." Most side effects associated with statins are minor and can be addressed by adjusting the dose or switching to another type of statin, Nissen ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Lescol XL

Genetic High-Cholesterol Condition More Common Than Thought

Posted 14 Mar 2016 by Drugs.com

MONDAY, March 14, 2016 – Twice as many people as previously thought are genetically predisposed to develop dangerously high cholesterol levels, new research suggests. Familial hypercholesterolemia, as this condition is called, significantly ups the risk for an early heart attack. The study found it affects about one in every 250 American men and women, rather than one in 500. The new numbers don't reflect a problem on the rise, however, said study author Dr. Sarah de Ferranti, an assistant professor of pediatrics at Harvard Medical School. Instead, the condition was previously "under-recognized," she explained. For those who have this potentially deadly condition, "it is extremely important to get early, consistent preventive care," de Ferranti said. "The key is for you and your clinician to understand and distinguish between mild to moderately high cholesterol that comes on in middle ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Zetia, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Ezetimibe, Hyperlipoproteinemia Type IIa (Elevated LDL), Lescol, Hyperlipoproteinemia

Statins May Reduce Heart Risks Linked to Sleep Apnea: Study

Posted 6 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 6, 2016 – A new discovery about the way sleep apnea may raise the risk of heart disease also suggests that taking cholesterol-lowering statin drugs might reduce that risk, according to a new study. Sleep apnea is a common disorder that involves irregular breathing while asleep, with oxygen intake dropping frequently for brief periods. The condition can triple a person's risk of stroke, high blood pressure and other heart problems, said study author Dr. Sanja Jelic, an associate professor of medicine at Columbia University Medical Center in New York City. Statins such as Crestor (rosuvastatin) and Lipitor (atorvastatin) are already taken by millions of Americans to reduce their risk of heart disease. "If the beneficial effects of statins on blood vessel health in patients with obstructive sleep apnea is confirmed in larger clinical trials, obstructive sleep apnea may ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Sleep Apnea, Lovastatin, Zocor, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Cardiovascular Risk Reduction, Hyperlipoproteinemia Type IIa (Elevated LDL), Obstructive Sleep Apnea/Hypopnea Syndrome, Lescol

U.S. Task Force Backs Statins for Those 40 to 75 at Heightened Heart Risk

Posted 22 Dec 2015 by Drugs.com

MONDAY, Dec. 21, 2015 – Cholesterol-lowering statin drugs should be used to prevent a first heart attack or stroke in certain at-risk patients, according to a draft recommendation released Monday by the nation's leading experts in preventive medicine. The U.S. Preventive Services Task Force said statins can provide maximum preventive benefits for adults 40 to 75 years old who have an existing risk factor for heart disease and at least a 10 percent or greater risk of a heart attack or stroke sometime within the next 10 years. The independent panel added that people with a 10-year risk of heart attack and stroke between 7.5 percent and 10 percent might also benefit from statins, and should discuss the matter with their doctor. "Cardiovascular disease is a leading cause of death, and people with no signs or symptoms or past history of cardiovascular disease can still be at risk," said ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Lescol XL

U.S. Task Force Stays Neutral on Cholesterol Screening for Kids

Posted 22 Dec 2015 by Drugs.com

MONDAY, Dec. 21, 2015 – There's not enough evidence to recommend screening all children and teens for high cholesterol, experts say. It's not clear if such screening up to age 20 reduces the risk of cardiovascular disease in adulthood, the U.S. Preventive Services Task Force said in a draft recommendation released Monday. This is unchanged from a 2007 recommendation. "There is currently not enough research to determine whether screening all average-risk children and adolescents without symptoms leads to better cardiovascular health in adulthood," task force vice chair Dr. David Grossman said in a news release from the task force. "In addition, the potential harms of long-term use of cholesterol-lowering medication by children and adolescents are not yet understood," Grossman added. The task force is an independent, volunteer panel of national experts in prevention and evidence-based ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol, Lescol XL, Mevacor

Do Cholesterol Drugs Affect Aggression?

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – Cholesterol-lowering statin drugs might influence a person's aggressive behaviors, increasing or decreasing their irritability and violent tendencies, a new clinical trial suggests. Men taking statins typically become less aggressive, while women on statins tend to become more aggressive, according to findings published July 1 in the journal PLOS ONE. "Clinicians should be aware of this, and it's not bad for patients to be aware of it," said lead author Dr. Beatrice Golomb, a principal investigator at the University of California, San Diego School of Medicine. "If an individual develops a behavioral change, in my view medication should always be considered as a possibility." However, the effect appears to be minimal and needs to be verified with follow-up studies, said one outside expert, Robert Geffner, founding president of the Institute on Violence, Abuse & ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia, Lescol, Lescol XL

Half of U.S. Hispanics With High Cholesterol Unaware They Have It: Study

Posted 24 Jun 2015 by Drugs.com

WEDNESDAY, June 24, 2015 – Nearly half of Hispanic people in the United States with high cholesterol levels aren't aware they have the health problem and more than two-thirds who are aware aren't being treated, a new study indicates. Reviewing data from more than 16,000 Hispanics between the ages of 18 and 74, the researchers found that about 44 percent of men and 40 percent of women had high cholesterol, greater proportions overall than among the general U.S. population. Almost one-third of all American adults have high levels of low-density lipoprotein (LDL) or "bad" cholesterol, according to the U.S. Centers for Disease Control and Prevention, and less than a third have the condition under control. High cholesterol levels are a major risk factor for developing heart disease or stroke since a build-up of the fatty substance can narrow blood vessels and hinder blood flow to the heart ... Read more

Related support groups: High Cholesterol, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL)

Health Tip: What's Behind High Cholesterol?

Posted 24 Jun 2015 by Drugs.com

-- High cholesterol is a risk factor for serious health problems, from heart attack to stroke. The National Heart Lung and Blood Institute mentions these possible causes: Eating a diet high in cholesterol-rich foods, such as meat, cheese, egg yolks and other animal products. Foods high in saturated and trans fats also increase cholesterol. Being overweight or lack of physical activity can lead to extra pounds and boost cholesterol. Being age 55 or older increases your risk of high cholesterol. Having an inherited condition called familial cholesterolemia leads to high cholesterol. Read more

Related support groups: Obesity, High Cholesterol, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL), Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL)

Can U.S. Health-Care System Afford New, Improved Cholesterol Drugs?

Posted 18 Jun 2015 by Drugs.com

THURSDAY, June 18, 2015 – A new class of powerful cholesterol drugs is poised to hit the market, and doctors are both hopeful about their potential, and worried that insurers won't pay for them. The drugs, known as PCSK9 inhibitors, can drastically cut LDL cholesterol – the "bad" kind linked to increased risks of heart attack and stroke. And they are expected to open up a new option for people who cannot take statins, the drugs that have been the standard for cholesterol-lowering since the 1980s. Last week, an advisory panel to the U.S. Food and Drug Administration recommended the agency approve two PCSK9 inhibitors: alirocumab (Praluent) and evolocumab (Repatha). The FDA, which usually follows the recommendations of its advisory panels, is expected to OK both drugs. Some cardiologists have heralded PCSK9 inhibitors as a breakthrough – particularly for patients who can't take statins ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Zetia, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Ezetimibe, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Lescol

FDA Advisers Weigh Two New Cholesterol Drugs: Alirocumab and Evolocumab

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – U.S. health experts are weighing whether to endorse two drugs from a new class of cholesterol medications that seem to sharply cut "bad" LDL cholesterol in people who don't fare well on the commonly used drugs called statins. The new drugs are known as PCSK9 inhibitors. U.S. Food and Drug Administration advisers are meeting Tuesday and Wednesday to discuss and possibly recommend approval of the drugs alirocumab (Praluent) and evolocumab (Repatha). While the FDA isn't compelled to follow the recommendations of its advisory committees, it usually does so. A recent review of 24 clinical trials – published April 28 in the Annals of Internal Medicine – found that PCSK9 inhibitors lowered people's LDL cholesterol by about 47 percent, on average. More important, the drugs seemed to cut the risk of heart attack or death from heart disease, according to the ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Rosuvastatin, Red Yeast Rice, Pravachol, Livalo, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol, Lescol XL, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Mevacor, Baycol, Pitavastatin

Staying Fit May Delay Onset of High Cholesterol, Study Finds

Posted 11 May 2015 by Drugs.com

MONDAY, May 11, 2015 – Men who keep fit may find they delay normal age-related increases in blood cholesterol levels by up to 15 years, a new study suggests. It is common for cholesterol levels to rise with age and then decrease later in life, the study authors explained in background notes. Previous studies have shown that high cholesterol levels can be a risk factor for heart disease. Regular physical activity can lower this risk, the researchers said. "Exercise and being fit helps keep arteries clear by lowering 'bad' [LDL] cholesterol and boosting 'good' [HDL] cholesterol," explained study author Dr. Xuemei Sui, an assistant professor at the Arnold School of Public Health at the University of South Carolina in Columbia, S.C. "It also reduces other risk factors for atherosclerosis [narrowed arteries] and blood clots, such as high blood pressure, diabetes, obesity and stress," Sui ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Zetia, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Ezetimibe, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Lescol

Americans' Blood Triglyceride Levels Dropping: CDC

Posted 7 May 2015 by Drugs.com

THURSDAY, May 7, 2015 – Americans' levels of triglycerides – a type of fat in the blood – have dropped significantly in the past decade, according to a new federal study. Factors that may lower triglyceride levels include quitting smoking, weight loss, use of cholesterol-lowering drugs (such as statins) and improving dietary nutrition, the researchers said. "The news is encouraging," said Dr. Michael Miller, a professor at the University of Maryland School of Medicine in Baltimore. But Miller, who was not involved with the study, added that it is "certainly nothing to brag about when one out of every three middle-aged men 40 to 59, and nearly one out of every three women aged 60 and over continue to live with unhealthy triglyceride levels." Like the bad type of cholesterol – LDL – high levels of triglycerides raise the risk of clogged arteries and heart disease. Another expert, Dr. ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Atorvastatin, Crestor, Pravastatin, Lovastatin, Zocor, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Red Yeast Rice, Pravachol, Livalo, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol, Lescol XL, Mevacor

New Guidelines Would Greatly Boost Number of Young People on Statins

Posted 6 Apr 2015 by Drugs.com

MONDAY, April 6, 2015 – If all doctors followed new cholesterol guidelines aimed at children, almost half a million Americans aged 17 to 21 would be prescribed a cholesterol-lowering statin drug, a new study predicts. In 2011, the U.S. National Heart, Lung, and Blood Institute (NHLBI) issued new guidelines on reducing heart disease in adolescents and young adults. Those guidelines recommended that all people aged 17 to 21 get their blood levels of cholesterol checked, and statin treatment be initiated if cholesterol was at a certain level. In contrast, the American College of Cardiology (ACC) and American Heart Association (AHA) are sticking by adult-focused guidelines that more tightly restrict the use of statins for those under 40 years age. In the new study, researchers led by Dr. Holly Gooding of Boston Children's Hospital looked at data from more than 6,300 participants, aged 17 ... Read more

Related support groups: High Cholesterol, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL)

For Cholesterol Control, Experts Urge More Than Meds

Posted 29 Dec 2010 by Drugs.com

TUESDAY, Dec. 28 – Advances in medical science have made it easier than ever to lower dangerous cholesterol levels. A class of cholesterol-lowering drugs known as statins have proven particularly effective, reducing the risk for heart-related death by as much as 40 percent in people who have already suffered a heart attack, said Dr. Vincent Bufalino, president and chief executive of Midwest Heart Specialists and a spokesman for the American Heart Association. "People have said we need them in the drinking water because they are just so effective in lowering cholesterol," Bufalino said. But he and other doctors warn that when it comes to controlling cholesterol and enjoying overall health, nothing beats lifestyle changes, such as a heart-friendly diet and regular exercise. "Once we became a fast-food generation, it's just too easy to order it at the first window, pick it up at the ... Read more

Related support groups: High Cholesterol, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL)

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