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Related terms: Heartburn, Acid reflux, Esophageal Reflux, Gastroesophageal Reflux Disease, Pyrosis, Reflux, Heart Burn, Severe Heartburn

Study Suggests Heartburn Meds-Superbug Infections Link

Posted 27 Mar 2017 by Drugs.com

MONDAY, March 27, 2017 – Patients who take certain heartburn medications may be more likely to suffer recurrent bouts of a common "superbug" infection, a new study suggests. Proton pump inhibitors, such as Prilosec, Prevacid and Nexium, or so-called H2 blockers, such as Zantac, Pepcid and Tagamet, were linked to a 50 percent increased risk of developing multiple Clostridium difficile infections, researchers found. However, the study did not prove these heartburn medications cause recurrent C. difficile infections, just that an association appears to exist. And one specialist not involved with the study said the findings won't make him change his prescribing patterns. C. difficile can cause diarrhea and life-threatening inflammation of the colon. In the United States, about half a million people get sick from C. difficile each year. In recent years, these infections have become more ... Read more

Related support groups: Infections, GERD, Bacterial Infection, Omeprazole, Nexium, Prilosec, Pantoprazole, Zantac, Protonix, Ranitidine, Dexilant, Lansoprazole, Prevacid, Pepcid, Barrett's Esophagus, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole

Are Heartburn Meds During Pregnancy Linked to Asthma in Kids?

Posted 9 Jan 2017 by Drugs.com

MONDAY, Jan. 9, 2017 – Women who take certain heartburn medications during pregnancy may have a child at increased risk of developing asthma, new research suggests. For the new study, investigators analyzed eight studies that included more than 1.3 million children. The researchers found that kids born to mothers who were prescribed drugs for acid reflux during pregnancy were at least one-third more likely to have been seen by a doctor for asthma symptoms. Some of the medications come from drug classes that include Tagamet, Zantac, Prilosec, Nexium and Pepcid. "Our study reports an association between the onset of asthma in children and their mothers' use of acid-suppressing medication during pregnancy," said researcher Dr. Aziz Sheikh. He's co-director of the Asthma UK Center for Applied Research, at the University of Edinburgh in Scotland. "It is important to stress that this ... Read more

Related support groups: GERD, Asthma, Omeprazole, Nexium, Asthma - Maintenance, Prilosec, Pantoprazole, Indigestion, Zantac, Protonix, Ranitidine, Lansoprazole, Dexilant, Prevacid, Pepcid, Asthma - Acute, Delivery, Duodenitis/Gastritis, Aciphex, Famotidine

Heartburn Drugs May Raise Risk of Stomach Infections: Study

Posted 5 Jan 2017 by Drugs.com

THURSDAY, Jan. 5, 2017 – People who take heartburn drugs such as Prilosec and Nexium may be at increased risk of two potentially serious gut infections, a new study suggests. The study, of nearly 565,000 adults, found those on certain heartburn drugs had higher risks of infection with C. difficile and Campylobacter bacteria. Both bugs cause abdominal pain and diarrhea, but can become more serious – especially C. diff. According to the U.S. Centers for Disease Control and Prevention, almost half a million Americans were sickened by the infection in 2011, and 29,000 of them died within a month. The heartburn drugs in question included both proton pump inhibitors (PPIs) – brands like Prilosec, Prevacid and Nexium – and H2 blockers, such as Zantac, Pepcid and Tagamet, the study authors said. All suppress stomach acid production, and the researchers suspect that may make some people more ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Indigestion, Zantac, Protonix, Ranitidine, Lansoprazole, Dexilant, Prevacid, Pepcid, Duodenitis/Gastritis, Aciphex, Famotidine, Heartburn Relief, Rabeprazole, Esomeprazole, Zantac 150

Could Common Heartburn Drugs Up Stroke Risk?

Posted 15 Nov 2016 by Drugs.com

TUESDAY, Nov. 15, 2016 – A popular category of heartburn medications – including Nexium, Prevacid, Prilosec and Protonix – may increase your risk of stroke, a new study suggests. Known as proton pump inhibitors (PPIs), these drugs increased people's overall stroke risk by 21 percent, said study lead author Dr. Thomas Sehested. However, the risk appears to be driven by people who take high doses, added Sehested, research director at the Danish Heart Foundation in Copenhagen. "People treated with a low dose of PPIs did not have a high risk of stroke," he said. "Those treated with the highest doses of PPIs had the highest risk of stroke." The extent of risk also depends on the specific PPI taken. At the highest dose, stroke risk ranged from 30 percent for lansoprazole (Prevacid) to 94 percent for pantoprazole (Protonix), the researchers said. Takeda Pharmaceutical, the maker of ... Read more

Related support groups: GERD, Heart Disease, Ischemic Stroke, Omeprazole, Nexium, Dementia, Prilosec, Pantoprazole, Indigestion, Zantac, Protonix, Alzheimer's Disease, Ranitidine, Lansoprazole, Dexilant, Transient Ischemic Attack, Prevacid, Pepcid, Barrett's Esophagus, Duodenitis/Gastritis

FDA Medwatch Alert: Over-the-Counter Antacid Products Containing Aspirin: FDA Drug Safety Communication - Serious Bleeding Risk

Posted 7 Jun 2016 by Drugs.com

ISSUE: The FDA is warning consumers about the risk of serious bleeding when using nonprescription, also known as over-the-counter or OTC, aspirin-containing antacid products to treat heartburn, sour stomach, acid indigestion, or upset stomach. Many other products for these conditions are available that do not contain aspirin. These widely used products already contain warnings about this bleeding risk on their labels; however, we are continuing to receive reports of this serious safety issue. As a result, we will continue to evaluate this safety concern and plan to convene an advisory committee of external experts to provide input regarding whether additional FDA actions are needed. BACKGROUND: OTC aspirin-antacid products are sold under various trade names, including Alka-Seltzer Original, Bromo Seltzer, Medique Medi Seltzer, Picot Plus Effervescent, Vida Mia Pain Relief, Winco Foods ... Read more

Related support groups: GERD, Gas, Indigestion, Hangover, Alka-Seltzer Original, Medique Medi-Seltzer, Alka-Seltzer Lemon-Lime, Bromo Seltzer, Picot Plus, Aspirin/Citric Acid/Sodium Bicarbonate

Beware of Bleeding Risks With Antacids Containing Aspirin

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Antacids that contain aspirin may cause stomach or intestinal bleeding in rare cases, U.S. Food and Drug Administration officials said Monday. Since it issued a warning about serious bleeding risk with aspirin in 2009, the FDA has recorded eight new cases of serious bleeding caused by aspirin-containing antacid products sold over-the-counter, which include Alka Seltzer and Bromo Seltzer. In some of those cases, patients required a blood transfusion, the agency said in a news release. "Take a close look at the Drug Facts label, and if the product has aspirin, consider choosing something else for your stomach symptoms," Dr. Karen Murry Mahoney, deputy director of the division of nonprescription drug products, said in the release. "Unless people read the Drug Facts label when they're looking for stomach symptom relief, they might not even think about the possibility ... Read more

Related support groups: GERD, Aspirin, Ibuprofen, Naproxen, Advil, Aleve, Indigestion, Alcohol Dependence, Motrin, Excedrin, Tums, Milk of Magnesia, Aggrenox, Alka-Seltzer, Vicoprofen, Duodenitis/Gastritis, Caltrate, Alcoholism, Fiorinal, Excedrin Migraine

Health Tip: Is it Indigestion?

Posted 6 Jun 2016 by Drugs.com

-- If you've eaten too much or indulged in a food that's greasy, fatty or spicy, you may have an uncomfortable feeling known as indigestion. Here are common symptoms, courtesy of the Cleveland Clinic: A burning sensation in the stomach or upper abdomen. An acidic taste in the mouth. Pain in the abdomen. Occasional diarrhea. Bloatedness or gassiness. Vomiting or nausea. Growling stomach. Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Indigestion, Zantac, Protonix, Ranitidine, Lansoprazole, Dexilant, Prevacid, Pepcid, Tums, Milk of Magnesia, Duodenitis/Gastritis, Aciphex, Caltrate, Famotidine, Heartburn Relief

Health Tip: Talk to Your Doctor About Heartburn

Posted 31 May 2016 by Drugs.com

-- Your doctor can suggest ways to cope with heartburn, but it's up to you to start the conversation. The American Academy of Family Physicians suggests: Ask about recommended over-the-counter heartburn medications. Discuss possible causes and triggers of your heartburn, and what you can do to manage it. Talk about lifestyle changes that you can make. Ask about other health conditions that could be causing your heartburn. Discuss your favorite foods and whether they may be contributing to your heartburn. Read more

Related support groups: GERD, Indigestion, Duodenitis/Gastritis, Erosive Gastritis, Hypersecretory Conditions

Clues to How Popular Heartburn Drug Might Harm Arteries

Posted 10 May 2016 by Drugs.com

TUESDAY, May 10, 2016 – A popular over-the-counter heartburn medication accelerated aging of blood vessel cells in lab tests, raising red flags about its long-term effect on heart health, researchers say. Faster aging of blood vessel cells exposed to the antacid Nexium (esomeprazole) might potentially hinder the tasks these cells perform to prevent heart attack and stroke, the new study suggests. These lab results could explain why other studies have shown increased risk of heart disease in people who use proton pump inhibitors (PPIs) – the class of heartburn medication that includes Nexium, said study senior author Dr. John Cooke. "Our finding that the lining of blood vessels is impaired by proton pump inhibitors is a unifying mechanism for the reports that PPI users are at increased risk for heart attack, stroke and renal failure," said Cooke, chair of cardiovascular sciences at the ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Indigestion, Protonix, Lansoprazole, Dexilant, Prevacid, Tums, Milk of Magnesia, Duodenitis/Gastritis, Aciphex, Caltrate, Esomeprazole, Rabeprazole, Calcium Carbonate, Zegerid, Prevention of Cardiovascular Disease

Common Heartburn Drugs Linked to Kidney Disease in Study

Posted 15 Apr 2016 by Drugs.com

THURSDAY, April 14, 2016 – People who use certain drugs for chronic heartburn may be at increased risk of developing kidney disease, a new study suggests. The research is the latest to highlight potential risks from drugs called proton pump inhibitors (PPIs). PPIs include prescription and over-the-counter drugs, such as Prilosec, Prevacid and Nexium. But prolonged use of PPIs has been linked to certain nutrient deficiencies and bone-density loss. According to the U.S. Food and Drug Administration, bone fractures are considered a safety concern when people use PPIs for a year or more. More recently, research has hinted at additional hazards. Last year, for example, a study tied the medications to a slight increase in heart attack risk. However, neither that study nor this new one prove that PPIs are directly to blame for these problems. "I cannot say for certain that this is ... Read more

Related support groups: GERD, Omeprazole, Prilosec, Pantoprazole, Renal Failure, Protonix, Barrett's Esophagus, Chronic Kidney Disease, Zegerid, Prilosec OTC, Zegerid OTC, Omeclamox-Pak, Omeprazole/Sodium Bicarbonate/Magnesium Hydroxide, Protonix IV, Omeprazole/Sodium Bicarbonate, Renal and Genitourinary Disorders, Omesec, Amoxicillin/clarithromycin/omeprazole

Could a Low-Risk Surgery Help Your Chronic Heartburn?

Posted 30 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – A minimally invasive surgery to treat chronic heartburn is safer than generally believed, and could be a desirable alternative to long-term use of acid reflux medications, new research indicates. Scientists found the death rate following so-called laparoscopic fundoplication surgery for gastroesophageal reflux disease, or GERD, was far lower than the 1 percent often quoted. Experts contended the surgery might be underutilized, especially in light of increasing safety concerns about acid reflux drugs. "One of the main arguments against surgery when choosing between [drug] and surgical treatment for severe GERD is the risk of mortality," said study author Dr. John Maret-Ouda. He is a physician and doctoral student in upper gastrointestinal surgery at the Karolinska Institute in Sweden. But, "this study found only one death associated with [this surgery] among ... Read more

Related support groups: GERD, Indigestion, Gastrointestinal Disorders, Endoscopy, Barrett's Esophagus, Duodenitis/Gastritis, Gastric Bypass Surgery, Gastrointestinal Surgery, Erosive Gastritis, Duodenitis/Gastritis with Hemorrhage, Hypersecretory Conditions

Widely Used Heartburn Drugs Linked to Dementia Risk in Study

Posted 15 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – A popular class of heartburn medications might raise a senior's risk of dementia, a new study suggests. Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. But German researchers found that people 75 or older who regularly take the medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs. The study only found an association, however, and not a cause-and-effect link. "To evaluate cause-and-effect relationships between long-term PPI use and possible effects on cognition in the elderly, randomized, prospective clinical trials are needed," said corresponding author Britta Haenisch, from the German Center for Neurodegenerative Diseases in Bonn. In the meantime, "Clinicians should follow guidelines for PPI ... Read more

Related support groups: GERD, Gas, Omeprazole, Nexium, Dementia, Prilosec, Pantoprazole, Indigestion, Protonix, Alzheimer's Disease, Stomach Ulcer, Dexilant, Lansoprazole, Prevacid, Gastric Ulcer, Duodenitis/Gastritis, Aciphex, Peptic Ulcer, Prevpac, Esomeprazole

FDA Approves Takeda's Dexilant SoluTab (dexlansoprazole)

Posted 3 Feb 2016 by Drugs.com

DEERFIELD, Ill., Jan. 27, 2016 /PRNewswire/ – Takeda Pharmaceuticals U.S.A., Inc., (Takeda) (TSE: 4502) today announced that the United States (U.S.) Food and Drug Administration (FDA) approved Dexilant SoluTab delayed-release orally disintegrating tablets, a new formulation of dexlansoprazole that can be taken by allowing the tablet to melt in the patient's mouth. Dexilant SoluTab is a proton pump inhibitor (PPI) indicated for the treatment of heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD) and the maintenance of healed erosive esophagitis (EE) and relief of heartburn in adults 18 years and older. Dexilant SoluTab is a PPI with dual delayed release (DDR) technology that is designed to provide two separate releases of medication. "Our more than 20 years of leadership in gastroenterology has allowed us to provide another option that offers ... Read more

Related support groups: GERD, Dexilant, Dexlansoprazole

Heartburn Meds Linked to Chronic Kidney Disease

Posted 11 Jan 2016 by Drugs.com

MONDAY, Jan. 11, 2016 – A type of heartburn medication called proton pump inhibitors may be linked to long-term kidney damage, a new study suggests. Prilosec, Nexium and Prevacid belong to this class of drugs, which treat heartburn and acid reflux by lowering the amount of acid produced by the stomach. People who use proton pump inhibitors (PPIs) have a 20 percent to 50 percent higher risk of chronic kidney disease compared with nonusers, said lead author Dr. Morgan Grams, an assistant professor of epidemiology at Johns Hopkins University in Baltimore. The study was published Jan. 11 in JAMA Internal Medicine. The study doesn't establish a direct cause-and-effect relationship between the drugs and chronic kidney disease. However, Grams said, "We found there was an increasing risk associated with an increasing dose. That suggests that perhaps this observed effect is real." Proton pump ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Pantoprazole, Renal Failure, Protonix, Lansoprazole, Dexilant, Prevacid, Aciphex, Chronic Kidney Disease, Rabeprazole, Esomeprazole, Zegerid, Prilosec OTC, Dexlansoprazole, Prevacid SoluTab, Kapidex, Zegerid OTC

Health Tip: Struggling With Chronic Cough?

Posted 22 Dec 2015 by Drugs.com

-- Chronic cough occurs when you've been coughing steadily for eight weeks or longer. It's not always a sign of a serious health problem, but it can be annoying nonetheless. To help calm your chronic cough, the Mayo Clinic suggests: Avoiding exposure to allergens that are known to trigger your cough. Quitting smoking, which is a common cause of chronic bronchitis. Managing acid reflux, which can worsen cough. To help tame acid reflux, cut portion sizes, stay upright for several hours after eating, and sleep with the head of your bed elevated. Read more

Related support groups: Cough, GERD, Allergic Reactions, Allergies, Smoking, Smoking Cessation, Allergic Rhinitis, Hay Fever, Cough and Nasal Congestion, Anaphylaxis, Nasal Polyps, Oral Allergy Syndrome

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