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Related terms: Carcinoma, Malignant Disease, Malignant Tumor

Hopes Dashed for Rare Bone Cancer Treatment

Posted 1 day 19 hours ago by Drugs.com

FRIDAY, Aug. 26, 2016 – Adding extra drugs to chemotherapy doesn't benefit patients with a rare type of bone cancer, according to a new study. Osteosarcoma is diagnosed in about 600 people in the United States each year, mostly teenagers. With current treatments, only 65 to 70 percent of patients live three years after diagnosis without relapse or other cancers. Previous research suggested that more aggressive chemotherapy with extra drugs might help some patients, but this new study concluded that is not the case. "This trial matters because, in the past, we were treating a lot of patients with these drugs without realizing that they weren't helping," said lead author Dr. Neyssa Marina. She is a professor of pediatrics at Stanford University School of Medicine in Palo Alto, Calif. For the study, researchers assessed more than 600 osteosarcoma patients in 17 countries. Adding two drugs ... Read more

Related support groups: Cancer, Osteosarcoma, Diagnosis and Investigation, Osteogenic Sarcoma

Excess Weight Tied to Higher Risk for Many Cancers, Experts Say

Posted 2 days 22 hours ago by Drugs.com

WEDNESDAY, Aug. 23, 2016 – Staying slim throughout your life might lower your risk of developing at least eight types of cancer, an international cancer research group says. Those include cancers of the stomach, liver, gallbladder, pancreas, ovary and thyroid. The list also includes a form of brain cancer known as meningioma, as well as a type of blood cancer called multiple myeloma. What's more, the latest research builds on the findings of an earlier review by the International Agency for Research on Cancer (IARC), which is part of the World Health Organization. That research found that those who avoid gaining weight can curtail their risk for developing five other types of cancer, including cancer of the colon, esophagus, kidney, breast and uterus. "The review certainly concluded crystal clear, as you say, that obesity causes cancer," noted Dr. Graham Colditz, who chaired the IARC ... Read more

Related support groups: Obesity, Cancer, Breast Cancer, Renal Cell Carcinoma, Colorectal Cancer, Head and Neck Cancer, Urinary Tract Cancer

Cancer on Course to Become Top Killer of Americans

Posted 4 days ago by Drugs.com

WEDNESDAY, Aug. 24, 2016 – Cancer is on track to become the leading cause of death in the United States, closing in on heart disease as America's number one killer, a new government study shows. Heart disease has consistently been the leading cause of death for decades, and remained so in 2014, according to a report from the National Center for Health Statistics (NCHS) at the U.S. Centers for Disease Control and Prevention. But the gap between heart disease and the second-leading cause of death, cancer, has been narrowing since 1968, the researchers said. Cancer actually surpassed heart disease as the leading cause of death for 22 states in 2014, the study found. Back in 2000, Alaska and Minnesota were the only two states where cancer killed more people than heart disease. In addition, cancer is now the leading cause of death for a number of minority groups, including Hispanics, Asians ... Read more

Related support groups: Obesity, Cancer, Heart Disease, Smoking, Smoking Cessation, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Ischemic Heart Disease

Use of Cancer-Linked Fibroid Device Declines After FDA Warning

Posted 5 days ago by Drugs.com

TUESDAY, Aug. 23, 2016 – The use of power morcellators – cutting tools used in minimally invasive gynecological procedures – has dropped significantly for hysterectomies since the U.S. Food and Drug Administration warned against their use two years ago, a new study finds. Power morcellators have small blades that rotate rapidly. When used in minimally invasive hysterectomies or for the removal of noncancerous growths on the uterus known as fibroids, they slice the tissue into smaller pieces that are removed through a small opening in the abdomen. But tiny pieces of tissue can also spread to other areas of the body. And, sometimes, undetected cancers can be cut up with the healthy tissue. If that cancerous tissue isn't completely removed, those cells can cause cancer elsewhere. That's what prompted the FDA to issue its 2014 warning, the researchers explained. The new study looked only ... Read more

Related support groups: Surgery, Cancer, Hysterectomy, Ovarian Cancer, Uterine Leiomyomata / Fibroids, Genitourinary Surgical and Other Conditions, Urinary Tract Cancer

Fewer Cancer-Causing Chemicals in E-Cigs Than Regular Cigarettes: Study

Posted 9 days ago by Drugs.com

FRIDAY, Aug. 19, 2016 – Smokers who switch to electronic cigarettes get the same levels of nicotine, but lower levels of toxins and cancer-causing chemicals, new research shows. "This study suggests that smokers who completely switch to e-cigarettes and stop smoking tobacco cigarettes may significantly reduce their exposure to many cancer-causing chemicals," said lead author Maciej Goniewicz, an assistant professor of oncology at Roswell Park Cancer Institute in Buffalo, N.Y. The researchers recruited 20 daily-smoking adults who had smoked for an average of 12 years. For two weeks, they used e-cigarettes instead of tobacco cigarettes. During that time, their urine was analyzed for levels of nicotine and 17 "biomarkers" of toxins and carcinogens. Significant declines in 12 of the 17 biomarkers were noted during those two weeks. The declines were similar to those seen when people quit ... Read more

Related support groups: Cancer, Smoking, Smoking Cessation, Nicotine, Nicorette, Nicoderm CQ, Nicotrol Inhaler, Commit, Habitrol, Nicorelief, Nicorette DS, Nicotrol NS, ProStep, Nicotrol TD

Women's Cancer Risk Rises With Years Spent Overweight

Posted 12 days ago by Drugs.com

TUESDAY, Aug. 16, 2016 – The longer a woman is overweight, the higher her risk of several cancers, researchers report. The study, which followed nearly 74,000 U.S. women, found that the longer a woman carried excess poundage, the greater her risk of breast, endometrial, colon and kidney cancers. "We've known for a long time that excess weight is important in cancer risk," said Susan Gapstur, vice president of epidemiology for the American Cancer Society. The cancer society says excess weight contributes to as many as 20 percent of all cancer deaths. "This study is interesting because it suggests that the number of years you spend being overweight also matters," said Gapstur, who was not involved in the research. And that, she said, should provide further incentive to avoid excess weight gain in the first place. Currently, about 7 out of 10 adults in the United States are overweight, ... Read more

Related support groups: Obesity, Cancer, Breast Cancer, Weight Loss, Colorectal Cancer, Pancreatic Cancer, Ovarian Cancer, Bladder Cancer, Urinary Tract Cancer

Cancer Now Leading Killer in 12 European Nations

Posted 13 days ago by Drugs.com

MONDAY, Aug. 15, 2016 – Cancer has overtaken heart disease and stroke as the leading cause of death in 12 European countries, a new study reports. However, cardiovascular disease (heart disease and stroke) is still the leading cause of death worldwide, killing more than 17 million people a year, according to the study. In the 53 countries defined as the European region by the World Health Organization, heart disease killed more than 4 million people in 2016. Those deaths accounted for 45 percent of all deaths in those nations. Cancer accounted for less than half the number of deaths from heart disease in Europe as a whole, researchers said. However, success in preventing and treating heart disease seems to have led to large declines in heart disease deaths in a number of countries. Cancer now kills more men than heart disease in these 12 countries: Belgium, Denmark, France, Israel, ... Read more

Related support groups: Cancer, Heart Disease, Breast Cancer, Colorectal Cancer, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction

Cancer Survivors More Prone to Obesity, Study Finds

Posted 16 days ago by Drugs.com

FRIDAY, Aug. 12, 2016 – Obesity is more common among cancer survivors in the United States than in the general population, a new study finds. The problem is particularly high among survivors of colorectal and breast cancer, the study authors said. The researchers analyzed data gathered from nearly 539,000 American adults between 1997 and 2014. Among people with no history of cancer, 21 percent were considered obese in 1997, compared to 29 percent in 2014. Among cancer survivors, the obesity rate went from 22 percent to 32 percent over that time. Colorectal cancer survivors had the largest increases in obesity rates, followed by breast cancer survivors. The increases were particularly high among blacks who had survived colorectal, breast or prostate cancers, the findings showed. Specifically, for women who had survived colorectal cancer, the largest increases in obesity rates were among ... Read more

Related support groups: Obesity, Cancer, Breast Cancer, Colorectal Cancer

6 Million Americans Drink Carcinogen-Tainted Water: Report

Posted 19 days ago by Drugs.com

TUESDAY, Aug. 9, 2016 – Millions of Americans are exposed to unsafe levels of dangerous chemicals in their drinking water that may trigger a host of health problems, researchers report. Those health problems can range from cancer to higher cholesterol levels to compromised immune systems and hormonal disruptions, the scientists said. The levels of these chemicals, known as polyfluoroalkyl and perfluoroalkyl substances (PFASs), exceed government-recommended safety levels for at least 6 million people in the United States, the study found. "These chemicals may have complicated names, but people are exposed to them in nonstick cookware and packaging – things we use in our lives," said lead researcher Cindy Hu, from Harvard T.H. Chan School of Public Health's department of environmental health. "These chemicals have concerning health effects, and drinking water is one of the main ways ... Read more

Related support groups: Cancer, High Cholesterol, Poisoning, Toxic Reactions Incl Drug and Substance Abuse

Health Insurance Status May Affect Cancer Patients' Survival

Posted 20 days ago by Drugs.com

MONDAY, Aug. 8, 2016 – Two large studies suggest that surviving certain cancers in America could depend on your health insurance status. Despite improvements in cancer diagnosis and treatment, patients who were uninsured or had Medicaid coverage were more likely to suffer worse outcomes, compared with people who have other forms of health insurance, the studies found. People who were uninsured or relied on Medicaid were diagnosed at a later stage, received sub-optimal treatment and had shorter survival, the findings showed. In the case of testicular cancer, they were at greater risk of death from their disease than patients with other insurance, the researchers found. The findings, published online Aug. 8 in the journal Cancer, add to evidence linking poor outcomes and inadequate health insurance. Dr. Christopher Sweeney, a medical oncologist at the Dana-Farber Cancer Institute in ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Basal Cell Carcinoma, Brain Tumor, Melanoma, Skin Cancer, Pancreatic Cancer, Ovarian Cancer, Cervical Cancer, Melanoma - Metastatic

FDA Approves Merck’s Keytruda (pembrolizumab) for Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Posted 8 Aug 2016 by Drugs.com

KENILWORTH, N.J.--(BUSINESS WIRE)--August 5, 2016 Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved Keytruda (pembrolizumab), the company’s anti-PD-1 (programmed death receptor-1) therapy, at a fixed dose of 200 mg every three weeks, for the treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) with disease progression on or after platinum-containing chemotherapy. Under the FDA’s accelerated approval regulations, this indication for Keytruda is approved based on tumor response rate and durability of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in the confirmatory trials. For HNSCC patients, PD-L1 testing is not needed prior to use of Keytruda. The approval is based on data ... Read more

Related support groups: Cancer, Head and Neck Cancer, Keytruda, Pembrolizumab

Some Advanced Kidney Cancer Patients May Postpone Treatment

Posted 4 Aug 2016 by Drugs.com

THURSDAY, Aug. 4, 2016 – Not all adults with advanced kidney cancer that has spread require immediate, aggressive treatment, a small new study suggests. "A subset of adults with advanced kidney cancer have slow-growing disease that can be safely managed using active surveillance," explained study lead author Brian Rini, of the Cleveland Clinic's Taussig Cancer Institute. This "watch and wait" approach, instead of active treatment, "could spare them the inconvenience and debilitating side effects of aggressive treatments for about a year, and in some cases several years, without worsening anxiety and depression," Rini said in a news release from The Lancet Oncology. The journal published the findings Aug. 4. In advanced kidney cancer, drugs such as sunitinib and sorafenib are typically used. While they can slow disease progression, they do not cure it, the researchers said. Could some ... Read more

Related support groups: Cancer, Renal Failure, Chronic Kidney Disease, Sutent, Nexavar, Sunitinib, Sorafenib, Wilms' Tumor, Urinary Tract Cancer

Nearly 1 in 4 U.S. Seniors Has Some Form of Disability

Posted 3 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 3, 2016 – A new U.S. government report on aging finds that close to a quarter of Americans over 65 have some form of disability. "Many Americans enjoy longer lives, though with some functional limitations," according to a news release from the Federal Interagency Forum on Aging-Related Statistics, which authored the report. The Forum found that in 2014, "22 percent of the population age 65 and over say they have at least one limitation in vision, hearing, mobility, communication, cognition, or self-care." That finding means millions of Americans – often spouses or children – are becoming caregivers for disabled, aging loved ones. The report found that, in most cases, the burden isn't excessive. Overall, "about 86 percent reported that informal caregiving gives them satisfaction that the care recipient is well cared for," the Forum said. Caregivers often reported a ... Read more

Related support groups: Anxiety and Stress, Cancer, Cardiovascular Conditions and Disorders

Archeological Finds Push First Known Cancer Back 2 Million Years

Posted 29 Jul 2016 by Drugs.com

FRIDAY, July 29, 2016 – Researchers report that they have unearthed the earliest evidence of bone tumors and cancers, dating back almost 2 million years. The discoveries challenge the belief that cancer is a disease of modern life, the study authors said. "Modern medicine tends to assume that cancers and tumors in humans are diseases caused by modern lifestyles and environments. Our studies show the origins of these diseases occurred in our ancient relatives millions of years before modern industrial societies existed," said researcher Edward Odes. He is a doctoral candidate at the University of the Witwatersrand (Wits) in Johannesburg, South Africa. First, a 1.7-million-year-old foot bone with cancer was found at the Swartkrans cave in South Africa. The exact species is unknown, but it is a hominin, or bipedal human relative, the researchers said. Scientists also found a benign tumor ... Read more

Related support groups: Cancer, Osteosarcoma, Diagnosis and Investigation, Osteolytic Bone Metastases of Solid Tumors, Solid Tumors, Osteogenic Sarcoma

New Guidelines Issued for Cancer Patients' Post-Treatment Pain

Posted 29 Jul 2016 by Drugs.com

FRIDAY, July 29, 2016 – More people are surviving cancer, but many are left with persistent pain after treatment. New guidelines from the American Society of Clinical Oncology (ASCO) recommend that doctors routinely screen for such pain. The guidelines also advise doctors to consider the use of non-traditional treatments for pain. These include hypnosis, meditation and medical marijuana where it's legal. ASCO also cautioned doctors to assess patients' risk for overuse of opioid painkillers. "Many oncologists and primary care physicians are not trained to recognize or treat long-term pain associated with cancer," guideline panel co-chair Judith Paice said in an ASCO news release. "This guideline will help clinicians identify pain early and develop comprehensive treatment plans, using a broad range of approaches," she said. Advances in cancer diagnosis and treatment have led to a record ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, Cancer, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Codeine, Lortab, Tylenol, Opana, Chronic Pain, Ibuprofen, Subutex

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