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Breast Cancer Cells May Change When They Spread to Brain: Study

Posted 10 hours ago by Drugs.com

WEDNESDAY, Dec. 7, 2016 – When breast cancer spreads to the brain, important molecular changes may occur in the cancer, a small study found. The discovery of these changes could lead to improved diagnosis and treatment, the researchers said. About 20 percent of breast cancers are a type known as HER2-positive, which typically respond to targeted therapies. However, HER2-negative breast cancer that has spread to the brain doesn't respond to the same therapies. In this study, researchers analyzed tumors from 20 patients in the United States and Ireland. They found that primary breast cancer identified as HER2-negative switched to HER2-positive when it spread to the brain. The findings show that treatments should target not only the original breast cancer, but also brain tumors, said study author Adrian Lee, director of the Institute for Precision Medicine, part of the University of ... Read more

Related support groups: Breast Cancer, Estradiol, Premarin, Ethinyl Estradiol, Estrace, Arimidex, Femara, Vagifem, Breast Cancer, Metastatic, Estrace Vaginal Cream, Vivelle, Anastrozole, Climara, Letrozole, Estring, Vivelle-Dot, Premarin Vaginal, Aromasin, Herceptin, Estradiol Patch

Taking Breast Cancer Prevention Drug Beyond 5 Years May Not Raise Survival

Posted 15 hours ago by Drugs.com

WEDNESDAY, Dec. 7, 2016 – Many breast cancer survivors take anti-estrogen drugs for at least five years to help lessen their risk of recurrence. Now, new research suggests that taking such a drug for an even longer period might not confer any added benefit – at least in terms of survival. The study of thousands of older breast cancer survivors found that taking the aromatase inhibitor drug letrozole (Femara) for more than the recommended five years did not help them live longer. However, other benefits were noted, so the decision to extend use of drugs like these is one best made on a case-by-case basis, cancer specialists said. One oncologist who reviewed the new findings said the study has been "eagerly awaited," since many breast cancer survivors are counseled to take an aromatase inhibitor. "For now, this trial reinforces the need to listen to our patients and weigh out the risk ... Read more

Related support groups: Breast Cancer, Arimidex, Femara, Breast Cancer, Metastatic, Anastrozole, Letrozole, Aromasin, Exemestane, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Breast Cancer - Male, Osteolytic Bone Metastases of Breast Cancer, Teslac, Testolactone

Could White Wine Boost Your Melanoma Risk?

Posted 7 days ago by Drugs.com

THURSDAY, Dec. 1, 2016 – A new study raises the possibility that people who enjoy a glass of white wine every day may face a slightly elevated risk of melanoma. Total alcohol intake was associated with a 14 percent higher risk of melanoma per drink per day, researchers found. But, when they looked at the type of alcohol consumed, white wine emerged as the potential culprit. Each drink per day of white wine was associated with a 13 percent higher risk of melanoma, the researchers said. "Per drink" risk was based on 12.8 grams of alcohol – the median amount of alcohol in a beer, a glass of wine or a shot of spirits. Beer, red wine and liquor did not significantly affect melanoma risk, the study authors added. The study does not prove that white wine causes this deadly skin cancer. It merely shows an association, though one worth exploring, the researchers said. "We are just adding one ... Read more

Related support groups: Cancer, Breast Cancer, Alcohol Dependence, Colorectal Cancer, Alcoholism, Basal Cell Carcinoma, Melanoma, Skin Cancer, Hangover, Melanoma - Metastatic, Squamous Cell Carcinoma, Head and Neck Cancer, Breast Cancer, Prevention, Acute Alcohol Intoxication, History - Skin Cancer

Never Too Old for a Mammogram?

Posted 10 days ago by Drugs.com

MONDAY, Nov. 28, 2016 – Women who think they're too old to worry about mammograms may want to reconsider the age at which their breast cancer screening years are behind them, a new study suggests. Based on an analysis of nearly 7 million mammograms over a seven-year period, "the benefit continues with increasing age up until 90," said study author Dr. Cindy Lee. She is an assistant professor in residence at the University of California, San Francisco. The question of when to stop having mammograms has been widely debated. In 2009, the U.S. Preventive Services Task Force issued new guidelines, saying there wasn't enough evidence to assess the balance of benefits and harms of screening mammography in women aged 75 and older. Lee and her colleagues looked at patient age, mammogram results, recall rates for more testing, biopsy referrals and biopsy results. The investigators also looked at ... Read more

Related support groups: Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Body Imaging

Depressed Women Less Likely to Get Best Breast Cancer Care: Study

Posted 20 days ago by Drugs.com

FRIDAY, Nov. 18, 2016 – Breast cancer patients with a history of depression are less likely to receive recommended care for their disease, a new study finds. The study included more than 45,000 Danish women diagnosed with early stage breast cancer between 1998 and 2011. Of those, 13 percent had been treated with antidepressants and 2 percent had previously visited a hospital for depression. Compared with those who never took antidepressants, patients who used antidepressants were much less likely to receive recommended breast cancer treatments and had shorter overall survival, according to Dr. Nis Suppli, of the Danish Cancer Society Research Center in Copenhagen, Denmark, and colleagues. In addition, the researchers found that antidepressant use was tied to shorter breast cancer-specific survival: five years after cancer diagnosis, 13 percent of patients who used antidepressants had ... Read more

Related support groups: Depression, Major Depressive Disorder, Breast Cancer, Dysthymia, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative

New Drug May Brighten Outlook for Advanced Breast Cancer

Posted 16 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 16, 2016 – A recently approved drug can help slow the progression of advanced breast cancer, a new clinical trial confirms. The drug, called palbociclib (Ibrance), was approved in the United States last year for treating advanced cases of ER-positive breast cancer. That means the cancer uses the hormone estrogen to help fuel its growth. The approval was based on an earlier-stage study where the drug, used along with a standard drug called letrozole (Femara), helped keep women's cancer at bay. Palbociclib doubled the time patients remained progression-free compared to letrozole alone. The new findings, published in the Nov. 17 New England Journal of Medicine, confirm the earlier results in a larger group of women. "We found that the degree of clinical benefit was, again, remarkable," said lead researcher Dr. Richard Finn, an assistant professor of medicine at the ... Read more

Related support groups: Breast Cancer, Femara, Breast Cancer, Metastatic, Letrozole, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Ibrance, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer, Palbociclib

Exercise Good for Cancer Patients During, After Treatment

Posted 15 Nov 2016 by Drugs.com

TUESDAY, Nov. 15, 2016 – Exercising during and after cancer treatment is safe and improves quality of life, fitness and physical functioning, new research indicates. Benefits occurred with all types of exercise, said study author Brian Focht. "Overall, resistance exercise, aerobic exercise – and even a combination of aerobic and resistance – resulted in improvement in fitness and quality of life and physical function," said Focht. He directs the exercise and behavioral medicine lab at the Ohio State University Comprehensive Cancer Center in Columbus. More than 15 million people in the United States are cancer survivors. That number is expected to rise to 20 million within 10 years, according to background information with the study. But current guidelines about exercise for cancer survivors are broad, suggesting simply that patients should try to be active, Focht noted. The study ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative

Self-Exam of Breast Should Be Thorough

Posted 12 Nov 2016 by Drugs.com

FRIDAY, Nov. 11, 2016 – There are five steps women should follow to ensure a monthly breast self-exam is effective, an expert says. "The most important thing about a breast self-examination is to know your breasts," said Dr. Laura Kruper, a breast cancer surgeon at City of Hope in Duarte, Calif. "Many women detect breast cancers or breast lumps themselves and that can be the beginning of an important conversation with your doctor." "Start by looking for differences between your breasts. Good breast self-exams should be concerned with both the look and feel of breasts. The look element should be performed while either standing or sitting in front of a mirror, with your clothes removed," she added in a City of Hope news release. "Examine both breasts and look for: visible lumps; any unusual differences between the two breasts; dimpling or indentations in the breast tissue; redness, ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Diagnosis and Investigation, Breast Cancer - Palliative, Fibrocystic Breast Disease

Vitamin D May Affect Breast Cancer Survival

Posted 10 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – Vitamin D levels may affect breast cancer patients' chances of survival, a new study suggests. Researchers analyzed data from nearly 1,700 breast cancer patients in California and found that higher vitamin D levels at diagnosis were associated with better overall survival. This link was strongest in premenopausal women. Researchers found lower vitamin D levels in patients with advanced-stage tumors and the lowest levels in premenopausal women with triple-negative cancer. Triple-negative cancer is the most common type of breast cancer found in women with changes in a gene called BRCA1. While the findings are consistent with previous studies, other factors may play a role and the study does not prove cause and effect, the researchers noted. "Our findings provide compelling observational evidence for inverse associations between vitamin D levels and risk of ... Read more

Related support groups: Breast Cancer, Vitamin D Deficiency, Breast Cancer, Metastatic, Breast Cancer, Prevention, Caltrate 600 with D, Breast Cancer - Palliative, Citracal + D, Calcium/Vitamin D, Citracal Petites, Oysco 500 with D, Rickets, Osteolytic Bone Metastases of Breast Cancer, Calcium 600 D, Citracal Creamy Bites, Calcet, Oyster Shell Calcium, Calcarb with D, Sedecal D, UPCal D, Calcio Del Mar

Intense Chemo Offers Little Benefit for Early Breast Cancer: Study

Posted 9 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – A more intense type of chemotherapy offers little benefit over standard chemotherapy for women with high-risk early breast cancer, European researchers report. Known as tailored dose-dense chemotherapy, the treatments are given over a shorter period of time without increasing the overall dose. It has been suggested as a way to improve the effectiveness of the treatment for early breast cancer. However, the European study did not find a difference in recurrence-free survival or overall survival after five years of follow-up. The investigators did find that the dose-dense group had better event-free survival, defined as the time to any breast cancer relapse, cancer in the opposite breast, other malignant growths or death from any cause. Despite the results, a U.S. breast cancer expert said there is still a role for the approach in certain women. Researchers from ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Zoladex, Breast Cancer, Metastatic, Anastrozole, Evista, Letrozole, Megestrol, Megace, Herceptin, Aromasin, Exemestane, Breast Cancer - Adjuvant

Breast, Cervical Cancer More Deadly in Developing Nations: Report

Posted 2 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 2, 2016 – Women in developing countries are more likely to die of breast and cervical cancer than those in richer nations, researchers report. But, they added, many of the deaths in these low- and middle-income countries could be prevented with cost-effective treatment. "The global community cannot continue to ignore the problem – hundreds of thousands of women are dying unnecessarily every year, and the need for affordable access to cancer care is projected to increase in the coming decades, as many of the poorest countries face rising rates of cancers," said study co-author Richard Sullivan. Sullivan is a professor of cancer and global health at King's College London in England. The number of breast cancer cases diagnosed worldwide could almost double, from 1.7 million in 2015 to 3.2 million by 2030 if urgent action is not taken, the researchers said. Meanwhile, the ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer

1 in 4 Seniors Doesn't Discuss End-of-Life Care

Posted 31 Oct 2016 by Drugs.com

MONDAY, Oct. 31, 2016 – More than one-quarter of American seniors have never discussed end-of-life care, a new study finds. "Despite decades of work to improve advance care planning, over a quarter of older adults have still not engaged in any type of discussion or planning for their end-of-life preferences or plans," said lead author Krista Harrison, a geriatrics research fellow at the University of California, San Francisco. The researchers looked at more than 2,100 Medicare beneficiaries aged 65 and older. Data from the group included self-reported age, gender, race/ethnicity, education, income, self-rated health, number of chronic conditions, disability in activities of daily living, and dementia. The researchers found that 60 percent of the beneficiaries said they'd had discussions on end-of-life care, 50 percent on power of attorney, and 52 percent on other advanced directives. ... Read more

Related support groups: Cancer, Breast Cancer, Dementia, Alzheimer's Disease, Colorectal Cancer, Endometrial Cancer, Mild Cognitive Impairment, Cervical Cancer, Stomach Cancer, Breast Cancer, Prevention, Breast Cancer - Palliative, Gastric Cancer

Breast Reconstruction Worthwhile for Older Women: Study

Posted 28 Oct 2016 by Drugs.com

FRIDAY, Oct. 28, 2016 – Older women who have had a breast removed due to cancer benefit as much as younger women from breast reconstruction, a new study shows. Since the researchers also found that older women did not suffer more complications than younger women, age alone should not disqualify a woman from having the surgery, they added. Their study involved more than 1,500 women in the United States and Canada who had breast reconstruction after breast removal (mastectomy). The study authors included almost 500 women under age 45; about 800 between 45 and 60; and 234 over 60. Women in the two younger groups were just as satisfied with their new breasts as before the surgery while women 60 and older were slightly less so. Women who got breast implants had fewer complications than those whose own tissue was used for breast reconstruction. Among those who had implants, 22 percent of the ... Read more

Related support groups: Surgery, Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention

Rates of Preventive Mastectomy Doubled in a Decade, and Fear Is a Factor

Posted 18 Oct 2016 by Drugs.com

TUESDAY, Oct. 18, 2016 – Fear of cancer recurrence seems to be a primary reason why breast cancer patients choose to have their cancer-free breast removed at the same time as their affected breast, a new study finds. The rate of this type of surgery – called contralateral prophylactic mastectomy (CPM) – doubled in the United States in the past 10 years. Recent data suggest that up to 25 percent of newly diagnosed breast cancer patients undergo this procedure, the study authors noted. The researchers wanted to find out why so many patients decide to have the surgery. They looked at breast cancer patient postings in an online health community. Along with fear of cancer recurrence, many women believe that a double mastectomy is the best treatment for breast cancer, the investigators found. Some patients had already had a breast cancer recurrence and decided on preventive mastectomy in ... Read more

Related support groups: Surgery, Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative

Little Gains in Efforts to Boost Outpatient Care

Posted 17 Oct 2016 by Drugs.com

MONDAY, Oct. 17, 2016 – Efforts to improve the quality of care in the United States have had little impact on many aspects of outpatient care, a new, sweeping analysis shows. The researchers examined the quality of office-based care – meaning visits to physicians, physician assistants and nurse practitioners – between 2002 and 2013. Ongoing deficits in care "pose serious hazards to the health of the American public," the study authors concluded. One in four eligible Americans, for example, failed to receive recommended cancer screening. "That didn't change at all over 10 years and, in fact, got worse in places like mammography and cervical cancer screening," said study author Dr. David Levine. Levine is an internist and research fellow at Brigham & Women's Hospital and Harvard Medical School in Boston. Levine and his team also identified wasteful spending and possible harm due to ... Read more

Related support groups: Diabetes, Type 2, Cancer, Colonoscopy, Cervical Cancer, Breast Cancer, Prevention, Body Imaging

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