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Related terms: Metastatic Breast Cancer

Tamoxifen May Get Blamed for Unrelated Symptoms

Posted 1 day 9 hours ago by Drugs.com

FRIDAY, Dec. 9, 2016 – Some high-risk women who take tamoxifen to prevent breast cancer may mistake naturally occurring nausea and vomiting for side effects of the drug and stop taking it, a new study finds. Previous research has shown that taking tamoxifen can reduce the risk of breast cancer by more than 30 percent in high-risk women, and the preventive effects last more than 20 years, the study authors said. But a study of women taking tamoxifen in the United Kingdom found that one-third didn't continue the treatment for the recommended five years. Those who experienced nausea and vomiting were more likely to stop taking the drug than those without such symptoms, the findings showed. However, women who were taking an inactive placebo and had the same symptoms were equally likely to stop. That suggests that some symptoms triggered by other causes were being mistaken for side effects ... Read more

Related support groups: Breast Cancer, Tamoxifen, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer, Tamoxifen Hexal, Soltamox, Tamone, Tamoxen, Genox, Nolvadex D, Tamofen, Tamosin, Emblon, Nolvadex

Could a Computer Someday Guide Breast Cancer Care?

Posted 1 day 9 hours ago by Drugs.com

FRIDAY, Dec. 9, 2016 – An artificially intelligent computer system is making breast cancer treatment recommendations on a par with those of cancer doctors, a new study reports. The IBM computer system – called Watson Oncology – made treatment recommendations that jibed nine out of 10 times with those of a multidisciplinary board of doctors at a top cancer hospital in India, researchers say. In cases involving more complex cancers, however, the computer did not hit that 90 percent mark. Another version of Watson famously defeated two former winners on the game show "Jeopardy!" in 2011, winning a first-place prize of $1 million. In its oncology role, Watson digests a patient's medical history and current cancer data in under a minute. It then spends another minute reviewing all existing medical evidence regarding their particular form of cancer, said study co-author Dr. S.P. ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer, Breast Cancer - Male

Certain Breast Cancer Drugs Tied to Blood Vessel Damage

Posted 1 day 9 hours ago by Drugs.com

FRIDAY, Dec. 9, 2016 – Women on breast cancer drugs called aromatase inhibitors may show signs of early blood vessel damage that could lead to heart disease, a small study suggests. Researchers found that compared with healthy women their age, women on aromatase inhibitors were more likely to show signs of "endothelial dysfunction." That refers to problems in how the blood vessel lining responds to blood flow. The findings are based on just 36 women who were prescribed the drugs. And experts stressed it's too early to know what to make of the results. Still, the study adds to evidence linking aromatase inhibitors to elevated risks of high blood pressure, high cholesterol and possibly full-blown heart disease. Aromatase inhibitors include the drugs Aromasin (exemestane), Arimidex (anastrozole) and Femara (letrozole). These drugs work by lowering a woman's estrogen levels, and are often ... Read more

Related support groups: Heart Disease, Breast Cancer, Arimidex, Femara, Breast Cancer, Metastatic, Anastrozole, Letrozole, Aromasin, Exemestane, Breast Cancer, Prevention, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer, Infectious Heart Disease, Teslac, Testolactone

New Drug Combo Shows Promise Curbing Tough-to-Treat Breast Cancer

Posted 2 days 8 hours ago by Drugs.com

THURSDAY, Dec. 8, 2016 – In women with a certain form of tough-to-treat breast cancer, treatment with a combination of two drugs appeared to keep the cancer at bay longer – from about five months to 10, a new study says. The cancer is known as "advanced hormone receptor positive, HER 2 negative" breast cancer. Women with these tumors are often given drugs called aromatase inhibitors, which work by reducing estrogen in the body and slowing the growth of the cancer. However, patients commonly develop resistance to aromatase inhibitor drugs, and they stop working. This is also known as endocrine therapy resistance. The new research may offer these patients some hope, researchers said. "Our study has shown that combining a newer medicine called everolimus [Afinitor] with a more established medicine, fulvestrant [Faslodex], has demonstrated benefit in aromatase inhibitor resistant breast ... Read more

Related support groups: Breast Cancer, Estradiol, Premarin, Ethinyl Estradiol, Estrace, Arimidex, Femara, Vagifem, Estrace Vaginal Cream, Vivelle, Breast Cancer, Metastatic, Anastrozole, Climara, Letrozole, Estring, Premarin Vaginal, Vivelle-Dot, Aromasin, Afinitor, Estradiol Patch

Breast Cancer Cells May Change When They Spread to Brain: Study

Posted 3 days ago by Drugs.com

WEDNESDAY, Dec. 7, 2016 – When breast cancer spreads to the brain, important molecular changes may occur in the cancer, a small study found. The discovery of these changes could lead to improved diagnosis and treatment, the researchers said. About 20 percent of breast cancers are a type known as HER2-positive, which typically respond to targeted therapies. However, HER2-negative breast cancer that has spread to the brain doesn't respond to the same therapies. In this study, researchers analyzed tumors from 20 patients in the United States and Ireland. They found that primary breast cancer identified as HER2-negative switched to HER2-positive when it spread to the brain. The findings show that treatments should target not only the original breast cancer, but also brain tumors, said study author Adrian Lee, director of the Institute for Precision Medicine, part of the University of ... Read more

Related support groups: Breast Cancer, Estradiol, Premarin, Ethinyl Estradiol, Estrace, Arimidex, Femara, Vagifem, Estrace Vaginal Cream, Vivelle, Breast Cancer, Metastatic, Anastrozole, Climara, Letrozole, Estring, Premarin Vaginal, Vivelle-Dot, Aromasin, Estradiol Patch, Herceptin

Taking Breast Cancer Prevention Drug Beyond 5 Years May Not Raise Survival

Posted 3 days ago by Drugs.com

WEDNESDAY, Dec. 7, 2016 – Many breast cancer survivors take anti-estrogen drugs for at least five years to help lessen their risk of recurrence. Now, new research suggests that taking such a drug for an even longer period might not confer any added benefit – at least in terms of survival. The study of thousands of older breast cancer survivors found that taking the aromatase inhibitor drug letrozole (Femara) for more than the recommended five years did not help them live longer. However, other benefits were noted, so the decision to extend use of drugs like these is one best made on a case-by-case basis, cancer specialists said. One oncologist who reviewed the new findings said the study has been "eagerly awaited," since many breast cancer survivors are counseled to take an aromatase inhibitor. "For now, this trial reinforces the need to listen to our patients and weigh out the risk ... Read more

Related support groups: Breast Cancer, Arimidex, Femara, Breast Cancer, Metastatic, Anastrozole, Letrozole, Aromasin, Breast Cancer - Adjuvant, Exemestane, Breast Cancer, Prevention, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer, Breast Cancer - Male, Teslac, Testolactone

Depressed Women Less Likely to Get Best Breast Cancer Care: Study

Posted 18 Nov 2016 by Drugs.com

FRIDAY, Nov. 18, 2016 – Breast cancer patients with a history of depression are less likely to receive recommended care for their disease, a new study finds. The study included more than 45,000 Danish women diagnosed with early stage breast cancer between 1998 and 2011. Of those, 13 percent had been treated with antidepressants and 2 percent had previously visited a hospital for depression. Compared with those who never took antidepressants, patients who used antidepressants were much less likely to receive recommended breast cancer treatments and had shorter overall survival, according to Dr. Nis Suppli, of the Danish Cancer Society Research Center in Copenhagen, Denmark, and colleagues. In addition, the researchers found that antidepressant use was tied to shorter breast cancer-specific survival: five years after cancer diagnosis, 13 percent of patients who used antidepressants had ... Read more

Related support groups: Depression, Major Depressive Disorder, Breast Cancer, Dysthymia, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative

New Drug May Brighten Outlook for Advanced Breast Cancer

Posted 16 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 16, 2016 – A recently approved drug can help slow the progression of advanced breast cancer, a new clinical trial confirms. The drug, called palbociclib (Ibrance), was approved in the United States last year for treating advanced cases of ER-positive breast cancer. That means the cancer uses the hormone estrogen to help fuel its growth. The approval was based on an earlier-stage study where the drug, used along with a standard drug called letrozole (Femara), helped keep women's cancer at bay. Palbociclib doubled the time patients remained progression-free compared to letrozole alone. The new findings, published in the Nov. 17 New England Journal of Medicine, confirm the earlier results in a larger group of women. "We found that the degree of clinical benefit was, again, remarkable," said lead researcher Dr. Richard Finn, an assistant professor of medicine at the ... Read more

Related support groups: Breast Cancer, Femara, Breast Cancer, Metastatic, Letrozole, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Ibrance, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer, Palbociclib

Self-Exam of Breast Should Be Thorough

Posted 12 Nov 2016 by Drugs.com

FRIDAY, Nov. 11, 2016 – There are five steps women should follow to ensure a monthly breast self-exam is effective, an expert says. "The most important thing about a breast self-examination is to know your breasts," said Dr. Laura Kruper, a breast cancer surgeon at City of Hope in Duarte, Calif. "Many women detect breast cancers or breast lumps themselves and that can be the beginning of an important conversation with your doctor." "Start by looking for differences between your breasts. Good breast self-exams should be concerned with both the look and feel of breasts. The look element should be performed while either standing or sitting in front of a mirror, with your clothes removed," she added in a City of Hope news release. "Examine both breasts and look for: visible lumps; any unusual differences between the two breasts; dimpling or indentations in the breast tissue; redness, ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Diagnosis and Investigation, Fibrocystic Breast Disease

Vitamin D May Affect Breast Cancer Survival

Posted 10 Nov 2016 by Drugs.com

THURSDAY, Nov. 10, 2016 – Vitamin D levels may affect breast cancer patients' chances of survival, a new study suggests. Researchers analyzed data from nearly 1,700 breast cancer patients in California and found that higher vitamin D levels at diagnosis were associated with better overall survival. This link was strongest in premenopausal women. Researchers found lower vitamin D levels in patients with advanced-stage tumors and the lowest levels in premenopausal women with triple-negative cancer. Triple-negative cancer is the most common type of breast cancer found in women with changes in a gene called BRCA1. While the findings are consistent with previous studies, other factors may play a role and the study does not prove cause and effect, the researchers noted. "Our findings provide compelling observational evidence for inverse associations between vitamin D levels and risk of ... Read more

Related support groups: Breast Cancer, Vitamin D Deficiency, Breast Cancer, Metastatic, Breast Cancer, Prevention, Caltrate 600 with D, Breast Cancer - Palliative, Citracal + D, Calcium/Vitamin D, Rickets, Osteolytic Bone Metastases of Breast Cancer, Citracal Petites, Oysco 500 with D, Calcium 600 D, Citracal Creamy Bites, Calcet, Oyster Shell Calcium, Calcarb with D, Dical-D, Oysco D with Calcium, Caltrate Colon Health

Intense Chemo Offers Little Benefit for Early Breast Cancer: Study

Posted 9 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – A more intense type of chemotherapy offers little benefit over standard chemotherapy for women with high-risk early breast cancer, European researchers report. Known as tailored dose-dense chemotherapy, the treatments are given over a shorter period of time without increasing the overall dose. It has been suggested as a way to improve the effectiveness of the treatment for early breast cancer. However, the European study did not find a difference in recurrence-free survival or overall survival after five years of follow-up. The investigators did find that the dose-dense group had better event-free survival, defined as the time to any breast cancer relapse, cancer in the opposite breast, other malignant growths or death from any cause. Despite the results, a U.S. breast cancer expert said there is still a role for the approach in certain women. Researchers from ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Evista, Zoladex, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Casodex, Breast Cancer - Adjuvant

Breast, Cervical Cancer More Deadly in Developing Nations: Report

Posted 2 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 2, 2016 – Women in developing countries are more likely to die of breast and cervical cancer than those in richer nations, researchers report. But, they added, many of the deaths in these low- and middle-income countries could be prevented with cost-effective treatment. "The global community cannot continue to ignore the problem – hundreds of thousands of women are dying unnecessarily every year, and the need for affordable access to cancer care is projected to increase in the coming decades, as many of the poorest countries face rising rates of cancers," said study co-author Richard Sullivan. Sullivan is a professor of cancer and global health at King's College London in England. The number of breast cancer cases diagnosed worldwide could almost double, from 1.7 million in 2015 to 3.2 million by 2030 if urgent action is not taken, the researchers said. Meanwhile, the ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer

Breast Reconstruction Worthwhile for Older Women: Study

Posted 28 Oct 2016 by Drugs.com

FRIDAY, Oct. 28, 2016 – Older women who have had a breast removed due to cancer benefit as much as younger women from breast reconstruction, a new study shows. Since the researchers also found that older women did not suffer more complications than younger women, age alone should not disqualify a woman from having the surgery, they added. Their study involved more than 1,500 women in the United States and Canada who had breast reconstruction after breast removal (mastectomy). The study authors included almost 500 women under age 45; about 800 between 45 and 60; and 234 over 60. Women in the two younger groups were just as satisfied with their new breasts as before the surgery while women 60 and older were slightly less so. Women who got breast implants had fewer complications than those whose own tissue was used for breast reconstruction. Among those who had implants, 22 percent of the ... Read more

Related support groups: Surgery, Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention

Rates of Preventive Mastectomy Doubled in a Decade, and Fear Is a Factor

Posted 18 Oct 2016 by Drugs.com

TUESDAY, Oct. 18, 2016 – Fear of cancer recurrence seems to be a primary reason why breast cancer patients choose to have their cancer-free breast removed at the same time as their affected breast, a new study finds. The rate of this type of surgery – called contralateral prophylactic mastectomy (CPM) – doubled in the United States in the past 10 years. Recent data suggest that up to 25 percent of newly diagnosed breast cancer patients undergo this procedure, the study authors noted. The researchers wanted to find out why so many patients decide to have the surgery. They looked at breast cancer patient postings in an online health community. Along with fear of cancer recurrence, many women believe that a double mastectomy is the best treatment for breast cancer, the investigators found. Some patients had already had a breast cancer recurrence and decided on preventive mastectomy in ... Read more

Related support groups: Surgery, Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative

Breast Cancer Deaths Continue to Decline in U.S.

Posted 14 Oct 2016 by Drugs.com

THURSDAY, Oct. 13, 2016 – The racial gap for breast cancer deaths is closing, particularly among younger women, U.S. health officials reported Thursday. Breast cancer death rates are down overall for both white and black women, though there's still a disparity between the races. Between 2010 and 2014, death rates dropped faster among white women than among black women, about 2 percent a year versus 1.5 percent, according to the study from the U.S. Centers for Disease Control and Prevention. However, among women under 50, the death rate was the same for both races, the researchers found. "We hope that the signal we are seeing in younger women we will see in older women as time progresses," said lead author Dr. Lisa Richardson. She's director of the division of cancer prevention and control at the CDC. "Historically, black women have had higher mortality rates and they still do overall, ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative

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