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Related terms: Metastatic Breast Cancer

FDA Approves Talzenna (talazoparib) for gBRCAm HER2-Negative Locally Advanced or Metastatic Breast Cancer

Posted 5 days ago by Drugs.com

On October 16, 2018, the Food and Drug Administration approved talazoparib (Talzenna, Pfizer Inc.), a poly (ADP-ribose) polymerase (PARP) inhibitor, for patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), HER2‑negative locally advanced or metastatic breast cancer. Patients must be selected for therapy based on an FDA-approved companion diagnostic for talazoparib. A ...

Four Myths About Breast Cancer Debunked

Posted 13 days ago by Drugs.com

TUESDAY, Oct. 9, 2018 – There are four common myths about breast cancer that can affect prevention and treatment of the most common type of cancer in American women, an oncologist says. The first is believing you're not at risk because no one in your family has cancer. "Less than 10 percent of breast cancers are linked to genetics or linked to genes that you get from your family," said Dr. ...

Bills Mount for Breast Cancer Survivors

Posted 24 Aug 2018 by Drugs.com

FRIDAY, Aug. 24, 2018 – Surviving breast cancer is certainly its own reward, but a new study finds that many who do are saddled with thousands in out-of-pocket expenses for years. On average, breast cancer survivors get hit with an extra $1,100 in yearly out-of-pocket cancer-driven costs, researchers found. But interviews with 129 breast cancer survivors further revealed that the so-called ...

Study Explores New Way to Stop Cancer's Spread

Posted 22 Aug 2018 by Drugs.com

WEDNESDAY, Aug. 22, 2018 – Scientists say they're researching a way to destroy cancer cells that travel to other parts of the body. Many cancers become especially dangerous only when they spread (metastasize) from the initial location to other tissues such as the lungs, brain or bone, the University of Colorado Cancer Center researchers explained. The investigators found that when a crucial part ...

Breast Cancer Drug Promising in Phase 3 Trial

Posted 16 Aug 2018 by Drugs.com

WEDNESDAY, Aug. 15, 2018 – For women with advanced breast cancer who carry the BRCA1 and BRCA2 gene mutations, an experimental drug could improve survival, a new study suggests. The BRCA mutations are linked with a greater risk for aggressive breast and ovarian cancer. The drug, talazoparib, works by blocking an enzyme called poly ADP ribose polymerase (PARP), thus preventing cancer cells from ...

Triple-Negative Breast Cancer Genes ID'd

Posted 8 Aug 2018 by Drugs.com

WEDNESDAY, Aug. 8, 2018 – More genes associated with an increased risk of triple-negative breast cancer have been identified by researchers. Until now, only mutations in the BRCA1 gene have been linked with this type of breast cancer. "Triple-negative breast cancer is an aggressive type of cancer that cannot be treated using targeted therapies," study leader Fergus Couch, a geneticist at the ...

Heart Monitoring a Must for Breast Cancer Patients on Herceptin

Posted 7 Aug 2018 by Drugs.com

TUESDAY, Aug. 7, 2018 – The widely used chemotherapy drug trastuzumab (Herceptin) can be life-saving for women with HER2-positive breast cancer, a particularly aggressive form of the disease. But new research now adds to mounting evidence that the treatment can take a toll on the heart, increasing the risk for heart failure. The complication is uncommon, and in many cases, the benefits of the ...

Surgeons Make the Call on Gene Tests for Breast Cancer Patients

Posted 3 Jul 2018 by Drugs.com

TUESDAY, July 3, 2018 – When it comes to genetic testing for breast cancer patients, their surgeons wield great influence on that decision, new research shows. Genetic testing can provide important information that might affect treatment choices for breast cancer, but previous research shows that only about half of women who could benefit received such testing. This new study found that surgeons ...

Breakthrough Therapy Seems to Rid Woman of Advanced Breast Cancer

Posted 5 Jun 2018 by Drugs.com

TUESDAY, June 5, 2018 – Judy Perkins was 49 and battling breast cancer that had spread, but chemotherapy and hormone treatments had failed to rein in her disease. So, her doctors tried a highly sophisticated, but experimental, immunotherapy. It worked beyond their wildest expectations: Her body was cleared of all signs of cancer. And the research team that tried the cutting edge treatment hope ...

Experimental Drug, Taselisib, Shows 'Modest' Benefit in Slowing Advanced Breast Cancer

Posted 4 Jun 2018 by Drugs.com

SATURDAY, June 2, 2018 – A new and highly targeted drug slowed the growth of advanced breast cancers by about an average of two months, researchers report. "The findings in this study show a modest benefit to a subgroup of women with estrogen receptor-positive tumors," said Dr. Stephanie Bernik, a breast cancer specialist who wasn't involved in the research. Estrogen receptor-positive tumors are ...

Many Breast Cancer Survivors Not Getting Needed Mammograms

Posted 1 Jun 2018 by Drugs.com

THURSDAY, May 31, 2018 – After surviving a diagnosis of breast cancer, women still need regular screening. But many of them, especially black women, aren't getting the mammograms they need, a new study finds. It's essential to screen for a return of cancer so it can be treated before symptoms appear, the researchers explained. "The use of regular mammograms to detect a return of breast cancer ...

Breast Cancer Patients May Shorten Herceptin Regimen: Study

Posted 17 May 2018 by Drugs.com

WEDNESDAY, May 16, 2018 – For years, the drug Herceptin has helped women with an aggressive form of breast cancer beat the disease. But there's one downside: In a minority of cases, the drug can trigger heart damage. Now, a new study finds that women who need the drug might get away with taking a shorter, less toxic course of Herceptin. "This new trial shows that a shorter length of treatment ...

Earlier Mammograms May Mean Less Need for Aggressive Treatments

Posted 3 May 2018 by Drugs.com

THURSDAY, May 3, 2018 – Much of the debate over when to start having mammograms has focused on lives saved, but new research suggests that early screening might also translate into smaller tumors and less aggressive breast cancer treatments. "There are multiple benefits of mammography in terms of early detection. Not only do we save lives, but we reduce the likelihood of needing more aggressive ...

Breast Cancer Prognosis May Be Worse If Diagnosis Follows 'Negative' Mammogram

Posted 3 May 2018 by Drugs.com

THURSDAY, May 3, 2018 – About 15 percent of breast cancers are diagnosed in the interval between regularly scheduled mammograms, where the last mammogram showed no signs of a cancer. Now, new research suggests that these "interval cancers" may have a worse prognosis, especially for younger women. The take-home message is "that we need to identify patients at risk for an interval cancer and ...

End-of-Life Care Saves Money

Posted 30 Apr 2018 by Drugs.com

MONDAY, April 30, 2018 – Giving very ill and dying patients palliative care shortens hospital stays and lowers costs, researchers report. Palliative care focuses on providing relief from the symptoms and stress of a serious illness to reduce suffering for patients and their families. "People with serious and complex medical illness account heavily for health care spending, yet often experience ...

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