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Breast Cancer - Adjuvant News

'Nipple-Sparing' Mastectomies Don't Raise Odds of Cancer's Return: Study

Posted 9 days ago by Drugs.com

WEDNESDAY, July 19, 2017 – Surgeons performing mastectomies can offer a form of the procedure that allows women to retain the nipple for use in breast reconstruction. Now, a reassuring study finds that this type of mastectomy doesn't raise a woman's risk for breast cancer recurrence. "More women are requesting nipple-sparing mastectomy because of the superior cosmetic results. But doctors don't want to take any chances with breast cancer patients' safety for the sake of cosmetic improvement," explained lead researcher Dr. Barbara Smith. She's a surgical oncologist and director of the breast program at Massachusetts General Hospital in Boston. "Our study, which has one of the longest reported follow-ups after therapeutic nipple-sparing mastectomy in the United States, provides additional support that it's safe to leave the nipple intact during mastectomy with only a few exceptions," she ... Read more

Related support groups: Surgery, Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Surgical Prophylaxis, Osteolytic Bone Metastases of Breast Cancer, Breast Cancer - Male

Nerlynx Approved to Help Prevent Breast Cancer's Return

Posted 10 days ago by Drugs.com

TUESDAY, July 18, 2017 – Nerlynx (neratinib) has been approved by the U.S. Food and Drug Administration to help prevent HER2-positive breast cancer from returning. It's the first drug designed to prevent return of HER2-positive breast cancer, a genetic form of the disease that's particularly aggressive and can spread to other parts of the body, the agency said in a news release. The drug is meant for what's known as extended adjuvant therapy – given after initial treatment, to further reduce the risk that cancer will return. Breast cancer is the most common form of cancer in the United States, the FDA said. The disease is projected to be diagnosed in more than 250,000 women this year, and more than 46,000 are likely to die of the disease, according to the U.S. National Cancer Institute. Nerlynx, among a class of drugs designed to block enzymes that fuel cancer-cell growth, was ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Nerlynx, Neratinib

FDA Approves Nerlynx (neratinib) to Reduce the Risk of Breast Cancer Returning

Posted 10 days ago by Drugs.com

July 17, 2017 – The U.S. Food and Drug Administration today approved Nerlynx (neratinib) for the extended adjuvant treatment of early-stage, HER2-positive breast cancer. For patients with this type of cancer, Nerlynx is the first extended adjuvant therapy, a form of therapy that is taken after an initial treatment to further lower the risk of the cancer coming back. Nerlynx is indicated for adult patients who have been previously treated with a regimen that includes the drug trastuzumab. “HER2-positive breast cancers are aggressive tumors and can spread to other parts of the body, making adjuvant therapy an important part of the treatment plan,” said Richard Pazdur, M.D., director of the FDA’s Oncology Center of Excellence and acting director of the Office of Hematology and Oncology Products in the FDA’s Center for Drug Evaluation and Research. “Now, these patients have an option after ... Read more

Related support groups: Cancer, Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Nerlynx, Neratinib

FDA Widens Access to 'Cooling Cap' to Stop Hair Loss in Cancer Patients

Posted 5 Jul 2017 by Drugs.com

WEDNESDAY, July 5, 2017 – More cancer patients may be able to ward off hair loss during chemotherapy treatment. A cooling cap approved in 2015 for use in breast cancer patients has won expanded approval from the U.S. Food and Drug Administration. The DigniCap Cooling System can now be used for patients with solid tumors, the FDA announced. The computer-controlled cap contains liquid that circulates and cools the scalp, narrowing blood vessels. This reduces how much of the chemotherapy drugs reach hair follicle cells, the FDA said. Cooling also decreases activity of hair follicles and slows cell division. The result: Chemo drugs don't affect them as much, according to the FDA. Hair loss is a common side effect of chemotherapy, especially during treatment of most solid tumor cancers. Hair may fall out all at once, little by little or become thin. It's usually temporary – and upsetting. ... Read more

Related support groups: Depo-Provera, Provera, Breast Cancer, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Gleevec, Breast Cancer, Metastatic, Anastrozole, Letrozole, Megestrol, Zoladex, Evista, Megace, Tasigna, Sprycel, Herceptin

Many Women Mistaken on 'Side Effects' of Breast Cancer Drug

Posted 29 Jun 2017 by Drugs.com

THURSDAY, June 29, 2017 – Many women at high risk for breast cancer do not take the drug tamoxifen to prevent the disease, often because they confuse naturally occurring symptoms with side effects from the drug. That's the finding of a new study of nearly 4,000 women tracked for almost five years in the United Kingdom. One U.S. expert in breast cancer care wasn't surprised by the findings. "It is true that many women who take the drug are perimenopausal, and it appears that the symptoms the women experience may have nothing to do with the drug and are rather simply due to age," explained oncologist Dr. Stephanie Bernik. "This was already known by physicians, but it is always helpful to have a scientific report to back up the information you give a patient," said Bernik, who is chief of surgical oncology at Lenox Hill Hospital in New York City. Tamoxifen is used to treat women with any ... Read more

Related support groups: Hot Flashes, Breast Cancer, Menopausal Disorders, Tamoxifen, Postmenopausal Symptoms, Breast Cancer, Metastatic, Atrophic Vaginitis, Perimenopausal Symptoms, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Vaginal Dryness, Tamoxifen Hexal, Tamone, Tamoxen, Genox, Nolvadex D, Tamofen, Tamosin, Emblon, Nolvadex

New Microscope Scans Breast Tumors During Surgery

Posted 28 Jun 2017 by Drugs.com

WEDNESDAY, June 28, 2017 – A new microscope could help surgeons remove breast tumors completely, reducing the number of women who must undergo repeat surgeries to remove cancer cells that were missed the first time. The microscope, developed by scientists and engineers at the University of Washington, effectively scans tumors and examines cells in three dimensions in under 30 minutes, researchers report. "Pathologists are currently very limited in how much they can look at on a glass slide," study co-author Adam Glaser, a postdoctoral fellow in the UW Molecular Biophotonics Laboratory, said in a university news release. "If we can give them three-dimensional data, we can give them more information to help improve the accuracy of a patient's diagnosis." When removing a breast tumor, known as a lumpectomy, surgeons attempt to remove the cancer but spare as much healthy tissue as ... Read more

Related support groups: Surgery, Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Surgical Prophylaxis, Breast Cancer - Palliative

Medicaid Cuts Tied to Delayed Breast Cancer Diagnoses

Posted 26 Jun 2017 by Drugs.com

MONDAY, June 26, 2017 – As Congress takes aim at replacing "Obamacare," a new study says Medicaid cuts could boost the number of women diagnosed with late-stage breast cancer. The study looked at what happened after a budget crunch caused Tennessee to cut nearly 170,000 people from its Medicaid rolls in 2005. Within the next few years, the researchers found, late-stage breast cancer cases rose in low-income areas of the state. "We can't say that Medicaid disenrollment was the direct cause," said researcher Lindsay Sabik, an associate professor at the University of Pittsburgh. But, she said, there was clearly a correlation. The findings come at a crucial time: Republicans in both houses of Congress have proposed legislation that would cut off federal funding for Obamacare's expansion of Medicaid. Medicaid is a government program that helps millions of low-income Americans pay their ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative

Drug Helps Fight Breast Tumors Tied to 'Cancer Genes'

Posted 4 Jun 2017 by Drugs.com

SUNDAY, June 4, 2017 – A twice-daily pill could help some advanced breast cancer patients avoid or delay follow-up sessions of chemotherapy, a new clinical trial reports. The drug olaparib (Lynparza) reduced the chances of cancer progression by about 42 percent in women with breast cancer linked to BRCA1 and BRCA2 gene mutations, according to the study. Olaparib delayed cancer progression by about three months. The drug also caused tumors to shrink in three out of five patients who received the medication, the researchers reported. "Clearly the drug was more effective than traditional chemotherapy," said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society. "This is a group where a response is more difficult to obtain – a young group with a more aggressive form of cancer – and nonetheless we saw a close to 60 percent objective response rate," he said. The ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Lynparza, Olaparib

Drug Xeloda Prolongs Survival for Some Breast Cancer Patients

Posted 31 May 2017 by Drugs.com

WEDNESDAY, May 31, 2017 – A drug called Xeloda can extend the lives of some women whose breast cancer is not wiped out by standard treatment, a new clinical trial finds. Oncologists said the results are "practice-changing." "This drug is already approved, and we've been using it for a long time in cancer treatment," said Dr. Stephen Malamud, an oncologist at Mount Sinai in New York City. Xeloda (capecitabine) is a pill, so it's easy to take and is "much less toxic" than standard chemotherapy, noted Malamud, who was not involved in the new research. "Most importantly," he said, "it extended overall survival in this study." In 1998, Xeloda was approved in the United States for advanced breast cancer that had spread to distant sites in the body. The new trial, done in Japan and South Korea, tested the drug for a different group of patients. It focused on 910 women whose breast tumors were ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Xeloda, Herceptin, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Capecitabine, Breast Cancer - Palliative

Yoga, Meditation May Ease Some Breast Cancer Symptoms

Posted 19 May 2017 by Drugs.com

FRIDAY, May 19, 2017 – The diagnosis and treatment of breast cancer can come with a lot of anxiety, depression and other symptoms that affect quality of life. But mind-body therapies, such as yoga or meditation, may help ease these troubling concerns, a new study suggests. The researchers reviewed previous studies done on 80 integrative therapies. "We have good evidence that [some] mind-body therapies – such as meditation, yoga, relaxation – can provide benefit to breast cancer patients during and after treatment," said study researcher Heather Greenlee. She's an assistant professor of epidemiology at Columbia University's Mailman School of Public Health. "And we do have evidence that acupuncture is very useful in managing pain," she added. Evidence about dietary supplements and botanicals, however, are lacking when it comes to helping symptoms and side effects, she said. Greenlee ... Read more

Related support groups: Depression, Cancer, Major Depressive Disorder, Breast Cancer, Breast Cancer, Metastatic, Dysthymia, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Breast Cancer - Male, Osteolytic Bone Metastases of Breast Cancer

More Cancers Caught Early Since Obamacare

Posted 18 May 2017 by Drugs.com

THURSDAY, May 18, 2017 – More cancers have been spotted in their early stages since the Affordable Care Act (ACA) became the law of the land, new research finds. Finding breast, colon, cervical and lung cancers early greatly improves the odds of successful treatment, said study author Xuesong Han. She's the strategic director of health policy and health care delivery research at the American Cancer Society. "We wanted to see if the introduction of the ACA affected the diagnosis of these cancers," she said. Although the increase in early-stage cancer diagnosis was only 1 percent, it's a significant increase that includes thousands of patients whose cancer might not have been found until it was too late for effective treatment and potential cure, Han noted. The increases in diagnosis of lung and cervical cancer were mostly among people on Medicaid, she said. A large part of the ACA is ... Read more

Related support groups: Cancer, Breast Cancer, Lung Cancer, Colorectal Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Cervical Cancer, Breast Cancer, Prevention, Diagnosis and Investigation, Breast Cancer - Palliative, Osteolytic Bone Metastases of Breast Cancer

Could Tai Chi Ease Insomnia in Breast Cancer Survivors?

Posted 12 May 2017 by Drugs.com

FRIDAY, May 12, 2017 – For breast cancer survivors who struggle with sleep, a new study suggests that tai chi might calm their restless nights. Researchers found this slow-moving form of meditation was as good as talk therapy and more effective than medication in treating insomnia and reducing the risk for sleep loss-related health issues, including depression, fatigue and a weakened immune system. "Breast cancer survivors often don't just come to physicians with insomnia. They have insomnia, fatigue and depression," said study leader Dr. Michael Irwin. He directs UCLA's Cousins Center for Psychoneuroimmunology at the Semel Institute for Neuroscience and Human Behavior, in Los Angeles. "And this intervention, tai chi, impacted all those outcomes in a similar way, with benefits that were as robust as the gold standard treatment for insomnia [talk therapy]," Irwin added in a UCLA news ... Read more

Related support groups: Sleep Disorders, Insomnia, Fatigue, Breast Cancer, Breast Cancer, Metastatic, Drowsiness, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Hypersomnia, Breast Cancer - Palliative

Hope for 1st Drug Against Lymphedema, a Cancer Complication

Posted 10 May 2017 by Drugs.com

WEDNESDAY, May 10, 2017 – Many cancer patients, especially those who've undergone breast cancer treatment, experience painful, swollen limbs, a condition called lymphedema. Now researchers say they've found an underlying mechanism that could eventually lead to the first drug therapy for the debilitating condition. The findings come from research in mice and human cells. However, there's already a clinical trial underway to see whether these lab discoveries will translate into a new lymphedema treatment. It's estimated that 10 million Americans have lymphedema, said Dr. Stanley Rockson, one of the senior researchers on the study. "Even though many people might not recognize the term, it's a very common condition," said Rockson, a professor at Stanford University School of Medicine in Stanford, Calif. People with lymphedema have excess fluid buildup in parts of the body, usually the arms ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Ketoprofen, Breast Cancer, Prevention, Breast Cancer - Palliative, Orudis, Ketoprofen/lidocaine, Actron, Oruvail, Ketamine/ketoprofen/lidocaine, Orudis KT, Nexcede, Vopac, LidoProfen

Mammogram Guidelines Have Changed, But Are Doctors Listening?

Posted 10 Apr 2017 by Drugs.com

MONDAY, April 10, 2017 – Four of five doctors still recommend annual mammograms for women in their early 40s, despite guideline changes that have pushed back the age for yearly breast cancer screening, a new survey shows. Overall, 81 percent of physicians surveyed said they suggest annual mammograms for women aged 40 to 44, while more than two-thirds recommend regular mammograms for women aged 75 or older. "Gynecologists were, in general, more likely to recommend routine mammograms," added lead researcher Dr. Archana Radhakrishnan, an internist with Johns Hopkins University in Baltimore. These practices run counter to guidelines issued by the American Cancer Society, which recommends annual screening starting at 45 and screening every other year from age 55 onward, researchers said in background notes. The doctors also are ignoring the advice of the U.S. Preventive Services Task Force ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Body Imaging

Breast Cancer 'Immunotherapy' Helps Some With Tough-to-Treat Disease

Posted 3 Apr 2017 by Drugs.com

MONDAY, April 3, 2017 – Women with a particularly aggressive form of breast cancer who responded to an new immune-focused drug gained a significant survival benefit, a new study shows. The patients all had what's known as advanced, "triple-negative" breast cancers. "Triple-negative breast cancer is an aggressive subtype of breast cancer often affecting younger women and, unfortunately, the current treatment options for metastatic disease remain limited," explained Dr. Peter Schmid. He directs the Breast Centre at St. Bartholomew's Hospital and Barts Cancer Institute in London, England. However, oncologists also stressed that many women who took the new drug, called Tecentriq (atezolizumab), failed to respond. The results of this early, phase 1 trial were to be presented Monday at the annual meeting of the American Academy of Cancer Research (AACR), in Washington, D.C. The trial ... Read more

Related support groups: Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Tecentriq, Atezolizumab

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