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Related terms: Brain Cancer, Brain Tumor, metastatic, Cancer, Brain, Intracranial Tumors

Gene Therapy May Fight Brain Cancer's Return

Posted 27 Oct 2017 by Drugs.com

FRIDAY, Oct. 27, 2017 – A new form of gene therapy shows promise in battling recurrent brain cancer. The phase 1 clinical trial included 56 patients with recurrent high-grade glioma brain cancer. Three years after the gene therapy treatment, more than a quarter of the patients were still alive. Median survival for patients was 14.4 months, compared with eight months typically seen in patients. "Given the deadly nature of this disease, three-year survival is rarely reported in the recurrent setting. It is notable that the survival benefit was seen across a range of patients, and not just limited to patients with specific genetic mutations," said study author Dr. Clark Chen. Chen is head of the department of neurosurgery at the University of Minnesota Medical School. He made his comments in news release from the American Association for Cancer Research. The study was sponsored by therapy ... Read more

Related support groups: Fluorouracil, Efudex, Brain Tumor, Carac, Glioblastoma Multiforme, Pituitary Tumor, Diagnosis and Investigation, Acromegaly, Fluoroplex, Pituitary Adenoma, Malignant Glioma, Tolak, Anaplastic Oligodendroglioma, Adrucil, Diclofenac/fluorouracil, Anaplastic Astrocytoma, Fluorac, Efudex Occlusion Pack, Angioblastoma

Obesity Linked to 13 Types of Cancer

Posted 3 Oct 2017 by Drugs.com

TUESDAY, Oct. 3, 2017 – There's a link between obesity and 40 percent of all the cancers diagnosed in the United States, health officials reported Tuesday. That doesn't mean too much weight is causing all these cancer cases, just that there's some kind of still-to-be explained association, according to the U.S. Centers for Disease Control and Prevention. Still, the study findings suggest that being obese or overweight was associated with cancer cases involving more than 630,000 Americans in 2014, and this includes 13 types of cancer. "That obesity and overweight are affecting cancers may be surprising to many Americans. The awareness of some cancers being associated with obesity and overweight is not yet widespread," Dr. Anne Schuchat, CDC deputy director, said during a midday media briefing. The 13 cancers include: brain cancer; multiple myeloma; cancer of the esophagus; ... Read more

Related support groups: Obesity, Weight Loss, Colorectal Cancer, Brain Tumor, Ovarian Cancer, Pancreatic Cancer, Stomach Cancer

Fewer Uninsured Cancer Patients After Medicaid Expansion

Posted 27 Sep 2017 by Drugs.com

WEDNESDAY, Sept. 27, 2017 – States that expanded Medicaid under the Affordable Care Act halved the number of uninsured cancer patients, a new U.S. study finds. This matters because "uninsured cancer patients are more likely to go without needed care and treatment, such as radiation therapy or surgery to remove tumors," said study lead author Dr. Fumiko Chino. She is a radiation oncology resident at the Duke University School of Medicine. Chino and her colleagues analyzed the records of more than 197,000 cancer patients ages 18 to 64. All were newly diagnosed with cancer between 2011 and 2014 and received radiation as part of their treatment. The percentage of uninsured patients fell 52 percent on average in states that expanded Medicaid, while Medicaid enrollment rose from 15 to 18 percent. Medicaid is the publicly funded insurance program for the poor. In states that did not expand ... Read more

Related support groups: Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Brain Tumor, Skin Cancer, Cervical Cancer, Testicular Cancer, Solid Tumors

FDA OKs First 'Biosimilar' Drug to Fight Cancer, Mvasi

Posted 14 Sep 2017 by Drugs.com

THURSDAY, Sept. 14, 2017 – The first approval of a biosimilar drug to treat cancer was announced Thursday by the U.S. Food and Drug Administration. Mvasi (bevacizumab-awwb) was approved as a biosimilar to Avastin (bevacizumab) for the treatment of adults with certain colon, lung, brain, kidney and cervical cancers. A biosimilar is a biological product that is approved because it is highly similar to an already-approved biologic drug and has no significant differences in safety and effectiveness from the first product, the FDA explained. "Bringing new biosimilars to patients, especially for diseases where the cost of existing treatments can be high, is an important way to help spur competition that can lower health care costs and increase access to important therapies," FDA Commissioner Dr. Scott Gottlieb said in an agency news release. Mvasi is marketed by Amgen, Inc., headquartered in ... Read more

Related support groups: Cancer, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Brain Tumor, Avastin, Cervical Cancer, Bevacizumab, Mvasi

'Cancer Pen' Could Help Surgeons Spot Tumor Cells in Seconds

Posted 6 Sep 2017 by Drugs.com

WEDNESDAY, Sept. 6, 2017 – A new "cancer pen" promises to help surgeons immediately detect and completely remove cancerous tumor tissue, without having to send samples off to a lab for testing while the patient languishes on the table. The MasSpec Pen is a hand-held device that allows doctors to test in real-time whether tissue is cancerous or not, delivering results in about 10 seconds, researchers report. The pen will make it easier to surgically clear out all the cancer cells surrounding a tumor, explained senior researcher Livia Eberlin, an assistant professor of chemistry with the University of Texas at Austin. In particular, cancers such as those of the breast, pancreas and brain "tend to invade surrounding normal tissue," Eberlin said. "For a surgeon, it can be really tricky, because these cells resemble normal tissue. Just judging by [the] eye, it can be very challenging." The ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Brain Tumor, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Diagnosis and Investigation

Could the Zika Virus Help Battle a Deadly Brain Cancer?

Posted 5 Sep 2017 by Drugs.com

TUESDAY, Sept. 5, 2017 – The Zika virus is well known for causing devastating brain defects in fetuses. But what if scientists could use that ability to do something good? Researchers report that they think they might be able to harness the virus' attraction to developing brain cells – instead of adult brain cells – as a potential treatment for a deadly type of brain cancer. In lab and animal experiments, scientists from Washington University School of Medicine in St. Louis and the University of California, San Diego, showed – that the virus was able to target and destroy stem cells that drive the growth of a deadly and common type of brain tumor, known as a glioblastoma. "Our study is a first step towards the development of safe and effective strains of Zika virus that could become important tools in neuro-oncology and the treatment of glioblastoma," said study co-leader Michael ... Read more

Related support groups: Brain Tumor, Glioblastoma Multiforme, Insect Bites, Zika Virus Infection

Researchers ID Genes in Mice That Cause Aggressive Brain Cancer

Posted 14 Aug 2017 by Drugs.com

MONDAY, Aug. 14, 2017 – Researchers say they've identified specific gene combinations that can cause the aggressive brain cancer glioblastoma in mice. Using new technology that can also identify genetic triggers of other cancers, a Yale University-led team assessed the impact of mutations in more than 1,500 genetic combinations. They reported finding multiple combinations in living mice that could cause glioblastoma. Two of the mutations could make glioblastoma resistant to chemotherapy – a finding that could help doctors tailor treatments for individual patients, according to the researchers. "The human cancer genome is now mapped and thousands of new mutations were associated with cancer, but it has been difficult to prove which ones or their combinations actually cause cancer," co-corresponding author Sidi Chen said in a university news release. "We can also use this information to ... Read more

Related support groups: Cancer, Brain Tumor, Glioblastoma Multiforme, Diagnosis and Investigation

Childhood Cancer Radiation May Cause Unwanted Gene Mutation in Some

Posted 4 Aug 2017 by Drugs.com

FRIDAY, Aug. 4, 2017 – Some adult survivors of childhood cancer go on to develop brain tumors, and now researchers say they've found a gene mutation that seems to increase that risk. The researchers said their findings could lead to ways to prevent these brain tumors. Adults who had radiation to their head and spine to treat childhood cancer have a greater risk of meningiomas. These tumors, which are often benign, are the most common type of brain tumor in adults, according to the American Brain Tumor Association. In this study, Canadian researchers looked at 31 radiation-induced meningiomas in patients who underwent head and spine radiation during childhood. Most of them (74 percent) had survived either leukemia or pediatric brain cancer. These brain tumors were compared with 30 meningiomas among people in the general population. Gelareh Zadeh, the study's co-principal investigator, ... Read more

Related support groups: Brain Tumor, Diagnosis and Investigation, History - Radiation Therapy

Young Cancer Survivors Struggle to Resume Social Activities

Posted 1 Aug 2017 by Drugs.com

TUESDAY, Aug. 1, 2017 – Many young cancer survivors have trouble resuming their social lives. Researchers studied 215 cancer survivors between 14 and 39 years of age who completed questionnaires about their social functioning at four, 12 and 24 months after cancer diagnosis. About 1 in 3 reported low social functioning throughout the study period. The researchers said the difficulties might stem from the transition from treatment to "off-treatment survivorship, a time fraught with challenges." Those challenges include the negative impact of their disease and treatment on finances, body image, work plans, relationships with a spouse or significant other and plans for having children. Survivors with low scores on social functioning also had high levels of distress. The study "highlights the need to screen, identify and respond to the needs of high-risk adult-young adolescent patients at ... Read more

Related support groups: Anxiety, Anxiety and Stress, Cancer, Social Anxiety Disorder, Brain Tumor

Treatment Costs Can Be Another Blow to Cancer Patients

Posted 27 Jul 2017 by Drugs.com

THURSDAY, July 27, 2017 – The emotional and physical costs of cancer can be staggering. But the financial side of cancer is also a great burden, with many patients in the United States struggling to pay for treatment, new research reveals. "The current health law has greatly improved access to meaningful health coverage for cancer patients, survivors and all those with chronic diseases," Chris Hansen, president of the American Cancer Society Cancer Action Network, said in a network news release. "Yet costs remain a challenge for those facing cancer. Our country and our lawmakers should come together to find bipartisan solutions that begin to address patient costs without sacrificing the quality of coverage," he urged. Researchers surveyed financial navigators at 11 hospitals in nine states. Financial navigators – typically trained social workers or nurses – help cancer patients ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Breast Cancer, Lupron, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Gleevec, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Anastrozole, Brain Tumor, Letrozole, Skin Cancer, Tarceva

Sen. John McCain Has Brain Cancer

Posted 20 Jul 2017 by Drugs.com

THURSDAY, July 20, 2017 – Sen. John McCain, a respected longtime lawmaker, former prisoner of war and the Republican presidential nominee in 2008, has been diagnosed with an aggressive brain cancer. A statement released by McCain's office Wednesday night said the cancer, known as a glioblastoma, was discovered after a procedure to remove a blood clot above his left eye last week at Mayo Clinic Hospital in Phoenix. "Subsequent tissue pathology revealed that a primary brain tumor known as a glioblastoma was associated with the blood clot," the statement said. "Treatment options may include a combination of chemotherapy and radiation." McCain, 80, who has represented Arizona in the Senate since 1986, is known for his independent nature. He was a former Navy pilot who was captured, tortured and held for more than 5 years as a prisoner during the Vietnam War. "Senator John McCain has always ... Read more

Related support groups: Cancer, Brain Tumor, Glioblastoma Multiforme

Insured, But Still Barred From Top-Tier Cancer Centers

Posted 20 Jul 2017 by Drugs.com

THURSDAY, July 20, 2017 – Choosing a cheaper health plan could cost you access to cream-of-the-crop cancer doctors and facilities, a new study reports. Less-expensive "narrow network" health plans are much less likely to cover treatment by doctors at centers affiliated with the U.S. National Cancer Institute, said study lead author Laura Yasaitis. "We found that the narrower networks were more likely to systematically exclude NCI-affiliated physicians," said Yasaitis, a postdoctoral researcher with the University of Pennsylvania School of Medicine. "The oncologists they included in their networks were about half as likely to be NCI-affiliated as those they excluded." NCI-Designated Cancer Centers are the nation's top-flight facilities for cancer care, and studies have shown that patients treated at these centers tend to have better outcomes, Yasaitis said. Access to these centers is ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Brain Tumor, Cervical Cancer, Breast Cancer, Prevention, Head and Neck Cancer, Gastric Cancer

Senator McCain Faces a Tough Cancer Foe

Posted 20 Jul 2017 by Drugs.com

THURSDAY, July 20, 2017 – Sen. John McCain faces an uphill battle fighting the aggressive cancer discovered in his brain last week, experts say. The cancer, glioblastoma, is the most common malignant tumor that originates in brain cells, as opposed to cancers that spread to the brain from elsewhere in the body, said Dr. Manmeet Ahluwalia, dean of the Cleveland Clinic's Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center. But it's a very tough cancer to treat. Glioblastoma is difficult to surgically remove, resists attempts to kill it with radiation and chemotherapy, and nearly always comes back, cancer experts said. "The tumor many times responds to treatment initially but it tends to grow back," said Dr. Kurt Jaeckle, a neuro-oncologist and co-director of the Gerald J. Glasser Brain Tumor Center at Overlook Medical Center's Atlantic Neuroscience Institute in New Jersey. "It's ... Read more

Related support groups: Cancer, Brain Tumor, Glioblastoma Multiforme

Many Terminal Cancer Patients Remain in Denial

Posted 20 Jul 2017 by Drugs.com

WEDNESDAY, July 19, 2017 – Nearly 10 percent of patients with terminal cancer don't want to know they're dying, which can make their final days more difficult, a new study finds. Unwillingness to face poor prospects can lead to unnecessary treatments and keep patients from making end-of-life plans, the researchers reported recently in The Oncologist. "Health care professionals should appropriately assess patients' readiness for prognostic information," said study leader Siew-Tzuh Tang, a professor at Chang Gung University School of Nursing in Taiwan. Doctors should respect patients' reluctance to confront their poor prognosis if they are not ready to know, "but sensitively coach them to cultivate their accurate prognostic awareness," Tang said in a journal news release. The study involved nearly 250 terminal cancer patients in Taiwan. They were questioned several times over their last ... Read more

Related support groups: Anxiety, Generalized Anxiety Disorder, Anxiety and Stress, Cancer, Post Traumatic Stress Disorder, Social Anxiety Disorder, Breast Cancer, Prostate Cancer, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Non-Small Cell Lung Cancer, Brain Tumor, Breast Cancer, Metastatic, Skin Cancer, Ovarian Cancer, Pancreatic Cancer, Cervical Cancer, Breast Cancer, Prevention, Stomach Cancer

Doctors' Group Offers Ideas for Easing Cancer Costs

Posted 19 Jul 2017 by Drugs.com

WEDNESDAY, July 19, 2017 – New cancer drugs routinely cost $100,000 a year or more, and older cancer drugs are rising in price, too. Now, the American Society of Clinical Oncology (ASCO) has some suggestions for easing patients' money woes. The proposals include allowing Medicare to negotiate drug prices, legalizing the importation of drugs, and adopting bundled, or group, payment programs. In the new policy statement, ASCO also says it supports creation of a panel of "stakeholders" in health care to determine the effectiveness of its proposals. Such a group might also outline a uniform approach for assessing the value of drugs. "In what, undoubtedly, is one of the most difficult times in their lives, individuals with cancer should be focused on getting the best care possible, not worrying about financial strain on their families," said Dr. Clifford Hudis. He's CEO of ASCO, a leading ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Breast Cancer, Lupron, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Colorectal Cancer, Anastrozole, Brain Tumor, Votrient, Letrozole

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