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Related terms: Coagulopathy, Consumption coagulopathy, Disseminated Intravascular Coagulation (DIC), DIC

Nurses Learn How to Get Patients to Say 'Yes' to Blood Thinners

Posted 17 Aug 2017 by Drugs.com

THURSDAY, Aug. 17, 2017 – Online training for nurses increased hospital patients' use of medication that can prevent potentially deadly blood clots, a new study reveals. Nurses sometimes won't give the blood thinning drugs if patients don't want them. So researchers developed the training to teach nurses how to respond when patients say they don't want to take blood thinners. The study included more than 900 nurses at Johns Hopkins Hospital in Baltimore. After the online training, the number of patients who refused to take prescribed blood thinners dropped from 12.4 percent to 11.1 percent, the findings showed. "We teach in hopes of improving patient care, but there's actually very little evidence that online professional education can have a measurable impact. Our results show that it does," study senior author Dr. Elliott Haut said in a Johns Hopkins news release. Haut is vice chair ... Read more

Related support groups: Bleeding Disorder, Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Eliquis, Lovenox, Prevention of Thromboembolism in Atrial Fibrillation, Heparin, Rivaroxaban, Apixaban, Enoxaparin, Fragmin, Clexane, Arixtra, Hep-Pak, Dabigatran, Jantoven, Fondaparinux

Imbruvica Approval Expanded to Include Graft Versus Host Disease

Posted 3 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 2, 2017 – The U.S. Food and Drug Administration on Wednesday expanded approval for the anti-cancer drug Imbruvica (ibrutinib) to include adults with chronic graft versus host disease (cGVHD). cGVHD is a deadly condition that affects up to 70 percent of people who receive a stem cell transplant to treat cancers of the blood or bone marrow, the FDA said in a news release. The condition occurs when the transplanted cells attack healthy cells in a patient's tissues. "This approval highlights how a known treatment for cancer is finding a new use in treating a serious and life-threatening condition that may occur in patients with blood cancer who receive a stem cell transplant," said Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence. Use of Imbruvica to treat cGVHD was studied in a clinical trial of 42 people whose symptoms lingered despite standard ... Read more

Related support groups: Prednisone, Bleeding Disorder, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Dexamethasone, Cortisone, Triamcinolone, Betamethasone, Budesonide, Decadron, Blood Transfusion, Entocort, Solu-Medrol, Imbruvica, Entocort EC, Fludrocortisone, Florinef, Medrol Dosepak

10 Factors to Predict Bleeding Risk in Stroke Survivors

Posted 3 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 2, 2017 – Stroke survivors at high risk for bleeding from drugs meant to prevent another stroke can be identified using a new scoring system, new research contends. Many patients who have an ischemic stroke – which occurs when a clot blocks blood flow to the brain – are given drugs to prevent another clot. But these anti-clotting medications increase the risk of bleeding problems that can cause disability or death. In the new report, researchers analyzed data from six large studies of people who survived a stroke or mini-stroke (transient ischemic attack). Just over 43,000 people were included in the analysis. Of those, 1,530 had a major bleeding event – defined as bleeding within the skull or that led to death, a hospital stay or disability. The risk of such an event was 1.9 percent in the first year and 4.6 percent over three years, the investigators found. To ... Read more

Related support groups: Bleeding Disorder, Ischemic Stroke, Ischemic Stroke - Prophylaxis, Bleeding Associated with Coagulation Defect, Coagulation Defects and Disorders

FDA Approves New Drug, Endari, for Sickle Cell Disease

Posted 7 Jul 2017 by Drugs.com

FRIDAY, July 7, 2017 – The U.S. Food and Drug Administration on Friday approved the first new drug for sickle cell disease in nearly two decades. Endari (L-glutamine oral powder) helps reduce severe complications associated with the blood disorder, the agency said. Sickle cell disease is an inherited disorder in which the red blood cells are shaped like a sickle, which limits the flow of vital oxygen to organs and tissues. In turn, this triggers severe pain and organ damage. Approximately 100,000 Americans, mostly minorities, have sickle cell disease, according to the U.S. National Institutes of Health. "Endari is the first treatment approved for patients with sickle cell disease in almost 20 years," said Dr. Richard Pazdur, acting director of the Office of Hematology and Oncology Products at the FDA's Center for Drug Evaluation and Research. "Until now, only one other drug was ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Anemia, Anemia - Sickle Cell, Coagulation Defects and Disorders

Blood Shortage Prompts Call for Donations

Posted 6 Jul 2017 by Drugs.com

THURSDAY, July 6, 2017 – The American Red Cross needs your blood, and it needs it now. The group issued an emergency call for donations on Wednesday. Over the past two months, there have been about 61,000 fewer donations than what is needed, the organization said. "The decline in summer donations is causing a significant draw-down of our overall blood supply, and we urgently need people to give now to restock hospital shelves and help save lives," said Shaun Gilmore, president of Red Cross Biomedical Services. The July 4th holiday has been especially challenging: Nearly 700 fewer blood drives were held this week than during an average week. That's the equivalent of no blood drives nationwide for an entire day, the agency explained. "Every day, patients recovering from accidents or those receiving treatments for cancer or blood disorders rely on lifesaving blood products, regardless of ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Iron Deficiency Anemia, Blood Transfusion, Thalassemia, Coagulation Defects and Disorders, Blood Cell Transplantation

Study Tracks Bleeding Risk From Common Blood Thinners

Posted 28 Feb 2017 by Drugs.com

TUESDAY, Feb. 28, 2017 – Blood thinners can help prevent dangerous clots, but they also come with risks for excess bleeding. Now, new research shows that use of the medications does boost the odds of "subdural hematomas" – bleeds occurring within the skull and near the brain. And some blood thinners carry higher risk than others. The Danish research team stressed that the results don't mean patients who need blood thinners should avoid them altogether – just that their data adds to decisions around their use. "The present data add one more piece of evidence to the complex risk-benefit equation of [blood thinner] use," wrote a team led by Dr. David Gaist, of Odense University Hospital and the University of Southern Denmark. Despite the bleeding risk, "it is known that these drugs result in net benefits overall in patients with clear therapeutic indications," the study authors added. ... Read more

Related support groups: Bleeding Disorder, Aspirin, Warfarin, Coumadin, Plavix, Xarelto, Pradaxa, Eliquis, Clopidogrel, Excedrin, Aggrenox, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Ecotrin, Fiorinal with Codeine, Norgesic, Bayer Aspirin, Arthritis Pain Formula

Could a Therapy for Irregular Heartbeat Harm the Brain?

Posted 24 Jan 2017 by Drugs.com

TUESDAY, Jan. 24, 2017 – Catheter ablation is a common treatment for a form of irregular heartbeat known as premature ventricular contractions. Now, a small new study suggests the approach may put some patients at risk for brain injury. The findings are preliminary, but are "relevant to a large number of patients undergoing this procedure," study senior author Dr. Gregory Marcus said in a news release from the University of California, San Francisco. The study suggests that the procedure may help encourage the formation of brain lesions. Marcus, who directs clinical research at UCSF's department of cardiology, said he hopes the research "will inspire many studies to understand the meaning of and how to mitigate these lesions." The study included 18 patients who underwent catheter ablation for premature ventricular contractions (PVCs) – a type of abnormal heartbeat originating in a ... Read more

Related support groups: Bleeding Disorder, Arrhythmia, Diagnosis and Investigation, Brain Anomalies incl Congenital, Coagulation Defects and Disorders, Premature Ventricular Depolarizations, Head Imaging

Blood Banks Face Seasonal Shortages, New Screening Rules

Posted 23 Dec 2016 by Drugs.com

FRIDAY, Dec. 23, 2016 – There's typically a shortage of both blood and platelets during the holiday season. But, tighter testing for a rare complication of transfusions makes the need for platelets even more urgent, experts at UT Southwestern Medical Center in Dallas say. Platelets are a component of blood that are essential for clotting. The complication, called transfusion-related acute lung injury (TRALI), is the leading cause of death due to transfusions, the experts said. "One reason the supply of blood platelets has decreased is that we now have additional required testing of platelets after donation," said Dr. Thomas Froehlich, medical director at the Harold C. Simmons Comprehensive Cancer Center. Blood and platelet shortages are traditionally common during the holidays. The shortages put cancer patients undergoing chemotherapy, trauma victims and people with health issues that ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Anemia, Blood Transfusion, Folic Acid Deficiency, Coagulation Defects and Disorders, Bleeding Associated with Coagulation Defect, Anemia Associated with Chronic Disease, Blood Cell Transplantation

Taking a Holiday Trip? Protect Yourself From Blood Clots

Posted 16 Dec 2016 by Drugs.com

FRIDAY, Dec. 16, 2016 – Many Americans will travel afar to celebrate the holidays, potentially putting themselves at risk for deadly blood clots. Sitting for long periods in a car or airplane can limit blood circulation and cause a condition called deep vein thrombosis (DVT). In DVT, blood clots form in the deep veins of the lower legs and thighs. A clot can travel through the bloodstream and lodge in the brain, lungs, heart and other areas, causing severe organ damage and even death. But deep vein thrombosis is easy to prevent, according to Dr. Alan Lumsden, chief of cardiovascular surgery at Houston Methodist DeBakey Heart & Vascular Center. "If you plan to travel overseas or cross-country, make sure you get up and walk around at least every two hours, and try not to sleep more than four hours at a time. Drink plenty of water or juices, wear loose-fitting clothing, eat light meals ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Deep Vein Thrombosis (DVT), Pulmonary Embolism, Deep Vein Thrombosis, Deep Vein Thrombosis - First Event, Deep Vein Thrombosis - Recurrent Event, Deep Vein Thrombosis - Prophylaxis, Coagulation Defects and Disorders

Gene Therapy Offers Hope to Some Hemophilia Patients

Posted 6 Dec 2016 by Drugs.com

TUESDAY, Dec. 6, 2016 – Preliminary research suggests that a single dose of an experimental gene therapy may help patients with hemophilia B. As explained by the National Hemophilia Foundation, hemophilia B is a genetic disorder where people lack a protein needed for blood clotting called factor IX, or that the type of factor IX they produce is defective. The condition can lead to excess bleeding and occurs in about one in every 5,000 births, the foundation said. But researchers said they've never seen a medical treatment boost factor IX to the level seen in the new trial. According to the findings, patients who got the gene therapy were able to stop getting infusions of the clotting factor. "Our goal in this trial was to evaluate the safety of the gene therapy product and secondarily, to determine if we could achieve levels of factor IX that could decrease bleeding events in ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Hemophilia, Hemophilia B

Another Step Closer to Artificial Blood

Posted 4 Dec 2016 by Drugs.com

SATURDAY, Dec. 3, 2016 – Artificial blood stored as a powder could one day revolutionize emergency medicine and provide trauma victims a better chance of survival. Researchers have created an artificial red blood cell that effectively picks up oxygen in the lungs and delivers it to tissues throughout the body. This artificial blood can be freeze-dried, making it easier for combat medics and paramedics to keep on hand for emergencies, said senior researcher Dr. Allan Doctor. He is a critical care specialist at Washington University School of Medicine in St. Louis. "It's a dried powder that looks like paprika, basically," Doctor said. "It can be stored in an IV plastic bag that a medic would carry, either in their ambulance or in a backpack, for a year or more. When they need to use it, they spike the bag with sterile water, mix it, and it's ready to inject right then and there." The ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Anemia, Blood Transfusion, Diagnosis and Investigation, Coagulation Defects and Disorders, Blood Cell Transplantation

Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode: Study

Posted 2 Dec 2016 by Drugs.com

THURSDAY, Dec. 1, 2016 – Use of a blood thinner is routine for many heart patients, but these drugs come with a risk of episodes of excess bleeding. What, if any, anticoagulant (blood thinner) should these patients take after such episodes arise? A new study suggests that the blood thinner Pradaxa (dabigatran) may be a better choice than the standby drug warfarin in these cases. The reason: Pradaxa is less likely than warfarin to cause recurrent bleeding in patients who recently suffered a bleeding stroke or other major bleeding event, the researchers found. "Our results should encourage clinicians to seriously consider resuming anticoagulation among patients who survived a major bleeding event, particularly if the source of bleeding was identified and addressed," said study senior author Dr. Samir Saba. He's associate chief of cardiology at the University of Pittsburgh Heart and ... Read more

Related support groups: Bleeding Disorder, Warfarin, Coumadin, Ischemic Stroke, Xarelto, Pradaxa, Eliquis, Lovenox, Transient Ischemic Attack, Heparin, Rivaroxaban, Apixaban, Ischemic Stroke - Prophylaxis, Fragmin, Enoxaparin, Clexane, Arixtra, Intracranial Hemorrhage, Hep-Pak, Dabigatran

Testosterone Therapy May Be Linked to Serious Blood Clots

Posted 1 Dec 2016 by Drugs.com

WEDNESDAY, Nov. 30, 2016 – Testosterone treatment can increase a man's risk of potentially fatal blood clots, a new study suggests. Researchers found that men taking the male hormone seem to have a 63 percent increased risk of a blood clot forming in a vein, a condition known as venous thromboembolism (VTE). These clots can cause a heart attack, stroke, organ damage or even death, according to the American Heart Association. "Risk peaks rapidly in the first six months of treatment and lasts for about nine months, and fades gradually thereafter," said lead researcher Dr. Carlos Martinez of the Institute for Epidemiology, Statistics and Informatics in Frankfurt, Germany. Millions of American men currently use testosterone pills, gels or injections, hoping that the male hormone will boost their sex drive, stamina and strength. It's been known for a while that the estrogen in birth control ... Read more

Related support groups: Bleeding Disorder, Testosterone, Deep Vein Thrombosis (DVT), AndroGel, Testim, Deep Vein Thrombosis, Axiron, Androderm, Depo-Testosterone, Fortesta, Testopel, Sexual Deviations or Disorders, Testopel Pellets, Hypoactive Sexual Desire Disorder, Venous Thromboembolism, Coagulation Defects and Disorders, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation

Drug Combo for Irregular Heartbeat Might Raise Bleeding Risk

Posted 21 Nov 2016 by Drugs.com

MONDAY, Nov. 21, 2016 – Because the irregular heartbeat known as atrial fibrillation can trigger stroke-inducing clots, many patients are prescribed a blood thinner. But a new Canadian study suggests that combining one blood thinner, Pradaxa, with certain statin medications could raise the odds for bleeding in these patients. "An increase in the risk of bleeding requiring hospital admission or emergency department visits was seen with lovastatin [Mevacor] and simvastatin [Zocor] compared with the other statins," said study author Tony Antoniou, a pharmacist at St. Michael's Hospital in Toronto. His team tracked outcomes for nearly 46,000 patients ages 65 and older. All had atrial fibrillation and took Pradaxa (dabigatran) to reduce their risk of stroke. Those who also took either lovastatin or simvastatin had a 40 percent higher risk of bleeding than those who took other statins, the ... Read more

Related support groups: Bleeding Disorder, Atrial Fibrillation, Lipitor, Simvastatin, Crestor, Atorvastatin, Pradaxa, Pravastatin, Zocor, Lovastatin, Prevention of Thromboembolism in Atrial Fibrillation, Vytorin, Rosuvastatin, Pravachol, Livalo, Red Yeast Rice, Caduet, Simcor, Lescol, Dabigatran

Health Tip: Control a Bleeding Wound

Posted 9 Nov 2016 by Drugs.com

-- Rinsing a wound with cold water helps clean it, but it may not be enough to prevent infection. Bleeding is the body's natural way of cleansing a wound. Then again, too much bleeding isn't healthy either. Here's how to stop heavy bleeding, courtesy of the American Academy of Family Physicians: If available, use a sterile or clean piece of cloth, gauze or tissue. Hold the material over the wound, gently applying pressure. Have another piece of clean material on hand. If the bleeding soaks the first piece, apply another clean piece on top, but don't remove the first piece. Hold the clean material in place for another 20 minutes with firm pressure. Raise a bleeding leg or arm above the level of your heart. Read more

Related support groups: Bleeding Disorder, Scrapes, Coagulation Defects and Disorders, Wound Cleansing, Minor Cuts, Wound Debridement, Minor Skin Conditions

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