Uloric
Generic Name: febuxostat (fe BUX oh stat)
Brand Names: Uloric
What is Uloric?
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Uloric is a prescription medicine called a xanthine oxidase inhibitor that reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.
Uloric is used to treat high blood concentrations of uric acid in patients with gout.
Uloric may also be used for other purposes not listed in this medication guide.
Important information about Uloric
You should not use Uloric if you are allergic to febuxostat, or if you are also being treated with azathioprine (Azasan, Imuran), mercaptopurine (Purinethol), or theophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).
Before taking Uloric, tell your doctor if you have kidney disease, liver disease, diabetes, heart disease, or high blood pressure.
You may have an increase in gout symptom flares when you first start taking Uloric. For best results, keep taking the medication as directed. Your doctor may prescribe other gout medications for you to use during the first 6 months of treatment with Uloric.
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Uloric.
What should I discuss with my healthcare provider before taking Uloric?
You should not use Uloric if you are allergic to febuxostat, or if you are being treated with the any of the following medications:
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azathioprine (Azasan, Imuran);
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mercaptopurine (Purinethol); or
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theophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking Uloric, tell your doctor if you have:
- kidney disease;
- liver disease;
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heart disease, high blood pressure; or
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diabetes.
FDA pregnancy category C. It is not known whether Uloric is harmful to an unborn baby. Before taking Uloric, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether febuxostat passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take Uloric?
Take Uloric exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose of Uloric to make sure you get the best results from this medication.
You may have an increase in gout symptom flares when you first start taking Uloric. For best results, keep taking the medication as directed. Your doctor may prescribe other gout medications for you to use during the first 6 months of treatment with Uloric.
To be sure this medication is helping your condition, your blood may need to be tested often. Do not miss any follow-up visits to your doctor.
Store Uloric at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
An overdose of Uloric is not expected to produce life-threatening symptoms.
What should I avoid while taking Uloric?
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Uloric.
Uloric side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Uloric and call your doctor at once if you have any of these serious side effects:
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chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
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sudden numbness or weakness, especially on one side of the body;
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sudden headache, confusion, problems with vision, speech, or balance;
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pale skin, easy bruising or bleeding;
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hearing problems, ringing in your ears;
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nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
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blood in your urine; or
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urinating less than usual;
Less serious Uloric side effects may include:
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fever, chills, body aches, flu symptoms;
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upset stomach;
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dry mouth, thirst;
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blurred vision;
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dizziness, spinning sensation;
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joint pain, swelling, or stiffness;
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muscle pain; or
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mild skin rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Uloric?
There may be other drugs that can interact with Uloric. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about Uloric.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Uloric only for the indication prescribed
- Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
Copyright 1996-2009 Cerner Multum, Inc. Version: 1.03. Revision Date: 05/14/2009 10:16:30 AM.
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