Febuxostat Pregnancy and Breastfeeding Warnings

Febuxostat is also known as: Uloric

Febuxostat Pregnancy Warnings

Febuxostat has been assigned to pregnancy category C by the FDA. Febuxostat was not teratogenic in animal studies at high human doses; however, increased neonatal mortality and a reduction in the neonatal body weight gain were observed when pregnant rats were treated with oral doses up to 40 times the human equivalent. There are no adequate and well-controlled studies in pregnant women. Febuxostat is only recommended for use during pregnancy when benefit outweighs risk.

Febuxostat Breastfeeding Warnings

There are no data on the excretion of febuxostat into human milk. Febuxostat is excreted into the milk of lactating rats. The manufacturer recommends that caution be used when administering febuxostat to nursing women.

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