Treanda
Generic Name: bendamustine (BEN da MUS teen)
Brand Names: Treanda
What is Treanda?
Treanda is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body. It is classified as an alkylating agent and works by blocking the growth of cancer cells.
Treanda is used to treat chronic lymphocytic leukemia.
Treanda may also be used for other purposes not listed in this medication guide.
Important information about Treanda
You should not receive Treanda if you are allergic to bendamustine or mannitol (Osmitrol).Before you receive Treanda, tell your doctor if you have a weak immune system, fever or other signs of infection, a metabolic disorder or electrolyte imbalance, liver or kidney disease, or if you smoke.
Tell your doctor about all other medications you use, especially carbamazepine (Carbatrol, Equetro, Tegretal), cimetidine (Tagamet), ciprofloxacin (Cipro), fluvoxamine (Luvox), omeprazole (Prilosec), thiabendazole (Mintezol), or a barbiturate such as phenobarbital (Solfoton) and others.
Do not use Treanda without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. Tell your caregiver right away if you have a fever, chills, itching, or skin rash during or shortly after the injection.Other serious side effects to tell your doctor about include fever, chills, cough, sore throat, feeling short of breath, pale skin, easy bruising or bleeding, severe skin rash or itching, vomiting, diarrhea, pain, urinating less than usual, weak pulse, muscle weakness or stiffness, confusion, hallucinations, or white patches or sores inside your mouth or on your lips.
To be sure Treanda is not causing harmful effects, your blood may need to be tested on a regular basis. Your blood pressure may also need to be checked. Do not miss any scheduled appointments.
Before I receive Treanda
You should not receive Treanda if you are allergic to bendamustine or mannitol (Osmitrol).If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you receive Treanda, tell your doctor if you have:
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a weak immune system;
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fever or other signs of infection;
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a metabolic disorder or electrolyte imbalance;
- liver disease;
- kidney disease; or
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if you smoke.
How is Treanda given?
Treanda is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take at least 30 minutes to complete.
Treanda is usually given for 2 days in a row every 28 days. You may receive up to 6 treatments altogether. Follow your doctor's instructions.
You may be given other medications to help prevent certain side effects of Treanda.
To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your blood pressure may also need to be checked. Do not miss any scheduled appointments.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Treanda injection.
What happens if I overdose?
Seek emergency medical attention if you think you have received too much of this medicine.Overdose symptoms may include drowsiness, tremors, slow or shallow breathing, loss of balance or coordination, or seizure (convulsions).
What should I avoid while receiving Treanda?
Treanda can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.Treanda side effects
Some people receiving a Treanda injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you have fever, chills, itching, or skin rash during or shortly after the injection. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:-
fever, chills, body aches, flu symptoms;
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cough, sore throat, feeling short of breath;
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pale skin, easy bruising or bleeding, extreme weakness;
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severe skin rash or itching;
-
nausea, vomiting, diarrhea, loss of appetite, lower back pain, urinating less than ususal;
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slow heart rate, weak pulse, muscle weakness or stiffness;
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confusion, hallucinations; or
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white patches or sores inside your mouth or on your lips.
Less serious side effects may include:
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mild nausea, vomiting, constipation;
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dry mouth;
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drowsiness, tired feeling;
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headache; or
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weight loss.
This is not a complete list of Treanda side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect Treanda?
Tell your doctor about all other medications you use, especially:
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carbamazepine (Carbatrol, Equetro, Tegretal);
-
cimetidine (Tagamet);
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ciprofloxacin (Cipro);
-
fluvoxamine (Luvox);
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omeprazole (Prilosec);
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thiabendazole (Mintezol); or
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a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Solfoton).
This list is not complete and there may be other drugs that can interact with Treanda. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your doctor or pharmacist can provide more information about Treanda.
- Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
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