Visicol Side Effects

Generic name: sodium biphosphate / sodium phosphate

Note: This document contains side effect information about sodium biphosphate / sodium phosphate. Some of the dosage forms listed on this page may not apply to the brand name Visicol.

Some side effects of Visicol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to sodium biphosphate / sodium phosphate: oral solution, oral tablet, rectal enema

Get emergency medical help if you have any of these signs of an allergic reaction while taking sodium biphosphate / sodium phosphate: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sodium biphosphate and sodium phosphate and call your doctor at once if you have a serious side effect such as:

• rectal bleeding;

• no bowel movement after use;

• sores or ulcers around your rectum;

• seizure (black-out or convulsions);

• fast, slow, or uneven heart rate;

• urinating less than usual or not at all;

• drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting; or

• swelling, weight gain, feeling short of breath.

Less serious side effects of sodium biphosphate / sodium phosphate may include:

• bloating, stomach pain;

• tightness in your throat;

• dizziness; or

• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to sodium biphosphate / sodium phosphate: oral solution, oral tablet, rectal enema

Gastrointestinal

Gastrointestinal side effects associated with sodium biphosphate-sodium phosphate tablets have included bloating (up to 47%), nausea (up to 37%), abdominal pain (up to 30%), and vomiting (up to 10%). Anal irritation, diarrhea, nausea, and stomach cramps have been reported with the enema formulation. Possible side effects associated with the enema formulation have included vomiting, abdominal pain, abdominal distension, gastrointestinal pain, and anal discomfort.

Metabolic

Metabolic side effects associated with sodium biphosphate-sodium phosphate tablets have included changes in serum electrolytes (including phosphate, calcium, potassium, and sodium). Possible side effects associated with the enema formulation have included dehydration, hyperphosphatemia, hypocalcemia, hypernatremia, and metabolic acidosis.

Renal

Renal side effects associated with sodium biphosphate-sodium phosphate tablets have included renal impairment, increased blood urea nitrogen (BUN), increased creatinine, acute renal failure, acute phosphate nephropathy, nephrocalcinosis, and renal tubular necrosis during postmarketing experience.

Nervous system

Nervous system side effects have included dizziness and headache. Seizures have been reported during postmarketing experience.

Cardiovascular

Cardiovascular side effects associated with sodium biphosphate-sodium phosphate tablets have included arrhythmias during postmarketing experience.

Hypersensitivity

Hypersensitivity side effects associated with sodium biphosphate-sodium phosphate tablets have included anaphylaxis, rash, pruritus, urticaria, throat tightness, bronchospasm, dyspnea, pharyngeal edema, dysphasia, paresthesia, swelling of the lips and tongue, and facial swelling during postmarketing experience. Possible side effects associated with the enema formulation have included hypersensitivity and pruritus.

Respiratory

Respiratory side effects associated with sodium biphosphate-sodium phosphate tablets have included bronchospasm, dyspnea, and dysphagia during postmarketing experience; these side effects were associated with hypersensitivity reactions.

Other

Other possible side effects associated with the enema formulation have included chills, blistering, and stinging.

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