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Tropicamide ophthalmic Side Effects

For the Consumer

Applies to tropicamide ophthalmic: ophthalmic solution

As well as its needed effects, tropicamide ophthalmic may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking tropicamide ophthalmic, check with your doctor or nurse as soon as possible:

Symptoms of too much medicine being absorbed into the body
  • Clumsiness or unsteadiness
  • confusion
  • fast heartbeat
  • flushing or redness of face
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • increased thirst or dryness of mouth
  • skin rash
  • slurred speech
  • swollen stomach in infants
  • unusual behavior, especially in children
  • unusual drowsiness, tiredness, or weakness

Some tropicamide ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Blurred vision
  • headache
  • sensitivity of eyes to light
  • stinging of the eye when the medicine is applied

For Healthcare Professionals

Applies to tropicamide ophthalmic: compounding powder, ophthalmic solution


Ocular side effects associated with tropicamide ophthalmic have included transient stinging, blurry vision, photophobia, and superficial punctate keratitis. Increased intraocular pressure has been reported with mydriatic agents.[Ref]


Gastrointestinal side effects have included dry mouth, nausea, and vomiting.[Ref]

Nervous system

Nervous system side effects have included headaches, psychotic reactions, and behavioral disturbances.[Ref]


Cardiovascular side effects have included pallor, tachycardia, and vasomotor or cardiorespiratory collapse.[Ref]


Musculoskeletal side effects have included muscle rigidity.[Ref]


Hypersensitivity reactions (unspecified) have been reported.[Ref]


1. "Multum Information Services, Inc. Expert Review Panel"

2. "Product Information. Mydriacyl (tropicamide ophthalmic)." Allscripts Pharmaceutical Company, Vernon Hills, IL.

It is possible that some side effects of tropicamide ophthalmic may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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