Talwin Side Effects

Generic name: pentazocine

Note: This document contains side effect information about pentazocine. Some of the dosage forms listed on this page may not apply to the brand name Talwin.

Some side effects of Talwin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to pentazocine: injectable solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking pentazocine (the active ingredient contained in Talwin) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• skin or muscle changes, or a hard lump where the medicine was injected;

• confusion, hallucinations;

• feeling like you might pass out;

• weak or shallow breathing; or

• increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).

Less serious side effects of pentazocine may include:

• mild stinging from the injection;

• drowsiness, dizziness, headache, ringing in your ears;

• feeling restless or excited;

• nausea, vomiting, constipation;

• sleep problems (insomnia), strange dreams;

• warmth or redness under your skin;

• blurred vision;

• sweating; or

• mild itching or skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

For Healthcare Professionals

Applies to pentazocine: injectable solution

Nervous system

Nervous system side effects including sweating, dizziness, lightheadedness, hallucinations, sedation, euphoria, headache, confusion, and disorientation have been reported. Weakness, flushing, disturbed dreams, insomnia, and syncope have been reported infrequently. Tremor, chills, paresthesia, irritability, and excitement have been reported rarely.

Gastrointestinal

Gastrointestinal side effects including nausea and vomiting have been reported. Constipation has been reported infrequently. Abdominal distress, anorexia, and diarrhea have been reported rarely.

Hematologic

Depression of the white blood cell count is usually reversible.

Hematologic side effects including depression of the white blood cell count (especially granulocytes) and moderate transient eosinophilia have been reported.

Hypersensitivity

Hypersensitivity reactions including rash have been reported infrequently. Urticaria and edema of the face have been reported rarely. One instance of an apparent anaphylactic reaction has been reported.

Dermatologic

Dermatologic side effects including erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis have been reported rarely.

Cardiovascular

Cardiovascular side effects including a decrease in blood pressure and tachycardia have been reported infrequently.

Respiratory

Respiratory side effects including respiratory depression have rarely been reported.

Other

Other side effects including tinnitus have been reported.

Ocular

Ocular side effects including visual blurring and focusing difficulty have been reported infrequently.

Psychiatric

Psychiatric side effects including depression have been reported infrequently.

Genitourinary

Genitourinary side effects including urinary retention have rarely been reported.

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