Pentazocine use while Breastfeeding
Drugs containing Pentazocine: Talwin, Talwin Nx, Talacen, Talwin Compound
Pentazocine Levels and Effects while Breastfeeding
Summary of Use during Lactation
Because no information is available on the use of pentazocine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. If the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness, a physician should be contacted immediately.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Pentazocine can increase serum prolactin.[1][2] However, the prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Alternate Drugs to Consider
Acetaminophen, Ibuprofen, Morphine
References
1. Manner T, Kanto J, Scheinin H et al. Meptazinol and pentazocine: effects on prolactin, growth hormone and vasopressin levels in plasma. Pharmacol Toxicol. 1987;61:301-4. PMID: 3438224
2. Rolandi E, Barreca T. Effects of two analgesic opiates (methadone and pentazocine) on the serum prolactin levels in breast cancer. Acta Endocrinol (Copenh). 1978;88:452-4. PMID: 581016
Pentazocine Identification
Substance Name
CAS Registry Number
359-83-1
Drug Class
- Analgesics, Opioid
- Narcotics
- Narcotic Antagonists
- Opiates
Administrative Information
LactMed Record Number
380
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2011-01-04
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Pentazocine use during Pregnancy
- Pentazocine Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
