Serax Side Effects

Generic Name: oxazepam

Note: This document contains side effect information about oxazepam. Some of the dosage forms listed on this page may not apply to the brand name Serax.

Some side effects of Serax may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to oxazepam: oral capsule, oral tablet

Along with its needed effects, oxazepam (the active ingredient contained in Serax) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking oxazepam:

Rare
  • Abdominal or stomach pain
  • black, tarry stools
  • chest pain
  • chills
  • clay-colored stools
  • cough
  • dark urine
  • dizziness
  • fainting
  • fever with or without chills
  • headache
  • itching
  • light-colored stools
  • loss of appetite
  • nausea and vomiting
  • painful or difficult urination
  • rash
  • shakiness and unsteady walk
  • shakiness in the legs, arms, hands, or feet
  • shortness of breath
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stomach pain
  • swelling
  • swollen glands
  • unpleasant breath odor
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting of blood
  • yellow eyes or skin
Incidence not known
  • Being forgetful
  • confusion about identity, place, and time
  • cough or hoarseness
  • decreased awareness or responsiveness
  • false or unusual sense of well-being
  • fever and sore throat
  • general feeling of tiredness or weakness
  • hallucinations
  • loss of bladder control
  • loss of memory
  • lower back or side pain
  • nightmares
  • pale skin
  • problems with memory
  • severe sleepiness
  • trouble sleeping
  • unusual excitement, nervousness, restlessness, or irritability

Get emergency help immediately if any of the following symptoms of overdose occur while taking oxazepam:

Symptoms of overdose
  • Blurred vision
  • change in consciousness
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • drowsiness
  • loss of consciousness
  • loss of strength or energy
  • muscle pain or weakness
  • sweating
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusual weak feeling

Some side effects of oxazepam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare
  • Decreased interest in sexual intercourse
  • feeling of constant movement of self or surroundings
  • inability to have or keep an erection
  • increased in sexual ability, desire, drive, or performance
  • increased interest in sexual intercourse
  • loss in sexual ability, desire, drive, or performance
  • rash with flat lesions or small raised lesions on the skin
  • sensation of spinning
Incidence not known
  • Double vision
  • menstrual changes
  • seeing double

For Healthcare Professionals

Applies to oxazepam: oral capsule, oral tablet

Nervous system

Nervous system side effects are common, particularly at higher doses. These effects include drowsiness, psychomotor retardation, decreased reaction time, lightheadedness, confusion, somnolence, perspiration, and euphoria.

Some patients have a paradoxical (disinhibition) reaction to oxazepam in the first few weeks of therapy. This reaction is usually self-limited.

Other

Other side effects have included withdrawal symptoms as a result of abrupt cessation of oxazepam (the active ingredient contained in Serax) Withdrawal symptoms have included anxiety, insomnia, tremors, seizures and depression.

Withdrawal symptoms occur most commonly after prolonged therapy (6 months or more). Rare cases of withdrawal seizures have been reported in some patients after abrupt cessation of high doses. Psychological dependence on benzodiazepines may develop after prolonged administration. Patients with a history of substance abuse are particularly prone to develop psychological dependence.

Genitourinary

Genitourinary side effects including urinary incontinence and sexual dysfunction have been reported.

Hepatic

In patients with liver disease, monitoring of liver function tests during oxazepam (the active ingredient contained in Serax) therapy may be helpful.

Hepatic side effects including mildly elevated liver function tests have been reported.

Hematologic

Hematologic side effects including cases of leukopenia have been reported rarely. A case of pancytopenia has also been reported.

Periodic monitoring of blood counts may be helpful.

Hypersensitivity

Hypersensitivity side effects including diffuse exanthemas and urticaria have been reported rarely. A case of fixed drug eruptions has also been reported.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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