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Prevacid 24HR Side Effects

Generic name: lansoprazole

Medically reviewed by Drugs.com. Last updated on Jan 22, 2024.

Note: This document provides detailed information about Prevacid 24HR Side Effects associated with lansoprazole. Some dosage forms listed on this page may not apply specifically to the brand name Prevacid 24HR.

Applies to lansoprazole: oral capsule delayed release, oral powder for suspension, oral tablet disintegrating delayed release.

Serious side effects of Prevacid 24HR

Along with its needed effects, lansoprazole (the active ingredient contained in Prevacid 24HR) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lansoprazole:

More common

  • diarrhea
  • itching, skin rash

Less common

  • increased or decreased appetite
  • joint pain
  • nausea
  • stomach pain
  • vomiting

Rare

  • anxiety
  • blurred vision
  • chest pain or discomfort
  • colds
  • constipation
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • increased cough
  • lightheadedness, dizziness or fainting
  • mental depression
  • muscle pain
  • nervousness
  • pain or discomfort in the arms, jaw, back, or neck
  • pounding in the ears
  • rectal bleeding
  • slow or irregular heartbeat
  • sweating
  • unusual bleeding or bruising

Incidence not known

  • back or leg pains
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • bloating
  • bloody, black, or tarry stools
  • change in mental status
  • chest tightness
  • chills
  • clay colored stools
  • confusion
  • cough
  • dark or bloody urine
  • difficulty with swallowing
  • drowsiness
  • fast heartbeat
  • fever
  • general body swelling
  • hives
  • hoarseness
  • indigestion
  • loss of appetite
  • lower back or side pain
  • mood or mental changes
  • muscle cramps in the hands, arms, feet, legs, or face
  • muscle spasms (tetany) or twitching seizures
  • nosebleeds
  • numbness and tingling around the mouth, fingertips, or feet
  • painful or difficult urination
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pale skin
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • seizures
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stomach tenderness
  • swelling of the feet or lower legs
  • swollen or painful glands
  • trembling
  • trouble breathing
  • unusual tiredness or weakness
  • yellow eyes or skin

Other side effects of Prevacid 24HR

Some side effects of lansoprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • dizziness
  • headache

Less common

  • bleeding, blistering, burning, coldness, or discoloration of the skin
  • mild nausea

Rare

  • bad, unusual, or unpleasant (after) taste
  • bad breath
  • belching
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in taste
  • difficulty in moving
  • double vision
  • feeling of heat or warmth
  • flushing or redness of the skin, especially on the face and neck
  • lack or loss of strength
  • loss or thinning of the hair
  • mild diarrhea
  • mild headache
  • mild vomiting
  • persistent non-healing sore
  • reddish patch or irritated area
  • shiny bump
  • stomach discomfort or upset
  • swollen joints
  • white, yellow or waxy scar-like area

Incidence not known

  • decrease in passing urine (dribbling)
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficulty with speaking

For healthcare professionals

Applies to lansoprazole: compounding powder, intravenous powder for injection, oral delayed release capsule, oral granule for reconstitution, oral suspension, oral tablet disintegrating.

General

The most commonly reported side effects include headache, dizziness, fatigue, and malaise.[Ref]

Gastrointestinal

Pseudomembranous colitis may occur with triple therapy for the eradication of H. pylori.

The majority of patients with severe/protracted cases of diarrhea who discontinued treatment had symptom resolution.[Ref]

Dermatologic

Skin rashes, urticaria, and pruritus generally resolved upon discontinuation of therapy.[Ref]

Nervous system

Hepatic

Other

Respiratory

A definitive relationship between use of this drug and interstitial pneumonia has not been established.[Ref]

Musculoskeletal

Hematologic

Psychiatric

Cardiovascular

Metabolic

A definitive relationship between use of this drug and hyponatremia has not been established.[Ref]

Genitourinary

Hypersensitivity

Ocular

Renal

Some cases of interstitial nephritis resulted in renal failure.[Ref]

Endocrine

Oncologic

Immunologic

References

1. (2001) "Product Information. Prevacid (lansoprazole)." TAP Pharmaceuticals Inc

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare (2008) Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. https://cima.aemps.es/cima/publico/home.html

Further information

Prevacid 24HR side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.