Lansoprazole use while Breastfeeding
Drugs containing Lansoprazole: Prevacid, Prevpac, Prevacid SoluTab, Prevacid OTC, Prevacid 24HR, Prevacid NapraPAC 500, Prevacid NapraPAC, Prevacid IV, Prevacid NapraPAC 375
Lansoprazole Levels and Effects while Breastfeeding
Summary of Use during Lactation
Because no information is available on the use of lansoprazole during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
One case of elevated serum prolactin and galactorrhea was reported in a 21-year-old man. When omeprazole was substituted for lansoprazole, the serum prolactin decreased to the normal range and galactorrhea ceased.[1]
A 13-year-old girl with a recent history of bilateral galactorrhea and hyperprolactinemia from omeprazole and domperidone on separate occasions was given lansoprazole to prevent gastrointestinal irritation following intravenous diclofenac for a severe headache. After 3 days of lansoprazole therapy, she again developed galactorrhea and an elevated serum prolactin that returned to normal a week after discontinuing lansoprazole.[2]
Alternate Drugs to Consider
Cimetidine, Famotidine, Nizatidine, Omeprazole, Pantoprazole, Ranitidine, Sucralfate
References
1. Izquierdo Prieto OM, Moreno Alia E, Rosillo Gonzalez A. [Galactorrhea induced by lansoprazole]. Aten Primaria. 2004;34:325-6. PMID: 15491529
2. Jabbar A, Khan R, Farrukh SN. Hyperprolactinaemia induced by proton pump inhibitor. J Pak Med Assoc. 2010;60:689-90. PMID: 20726208
Lansoprazole Identification
Substance Name
CAS Registry Number
103577-45-3
Drug Class
- Anti-Ulcer Agents
Administrative Information
LactMed Record Number
411
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2010-10-04
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Lansoprazole use during Pregnancy
- Lansoprazole Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
