Nuedexta Side Effects

Generic Name: dextromethorphan / quinidine

Note: This page contains side effects data for the generic drug dextromethorphan / quinidine. It is possible that some of the dosage forms included below may not apply to the brand name Nuedexta.

It is possible that some side effects of Nuedexta may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to dextromethorphan / quinidine: oral capsule

As well as its needed effects, dextromethorphan / quinidine may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking dextromethorphan / quinidine, check with your doctor immediately:

Less common
  • Bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • chills
  • cough
  • diarrhea
  • difficult, burning, or painful urination
  • fever
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • rapid weight gain
  • runny nose
  • shivering
  • sore throat
  • sweating
  • tingling of the hands or feet
  • trouble sleeping
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • vomiting

If any of the following symptoms of overdose occur while taking dextromethorphan / quinidine, get emergency help immediately:

Symptoms of overdose
  • Aggressive and violent behavior
  • agitation
  • blurred vision
  • change in color vision
  • change in consciousness
  • chest pain or discomfort
  • confusion
  • confusion as to time, place, or person
  • continuing ringing or buzzing or other unexplained noise in the ears
  • decreased awareness or responsiveness
  • depression
  • difficulty seeing at night
  • dizziness or lightheadedness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • double vision
  • excitement
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • feeling of constant movement of self or surroundings
  • hallucinations
  • hearing loss
  • holding false beliefs that cannot be changed by fact
  • inability to move the eyes
  • increased blinking or spasms of the eyelid
  • increased sensitivity of the eyes to sunlight
  • irregular or slow heart rate
  • loss of consciousness
  • overactive reflexes
  • poor coordination
  • restlessness
  • seeing double
  • seizures
  • sensation of spinning
  • severe sleepiness
  • shakiness and unsteady walk
  • shivering
  • shortness of breath
  • sticking out of tongue
  • sweating
  • talking or acting with excitement you cannot control
  • trembling or shaking
  • trouble with breathing, speaking, or swallowing
  • twitching
  • uncontrolled eye movements
  • uncontrolled twisting movements of the neck, trunk, arms, or legs
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual excitement, nervousness, or restlessness
  • unusual facial expressions

Some dextromethorphan / quinidine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common
  • Bloated
  • excess air or gas in the stomach or intestines
  • full feeling
  • lack or loss of strength
  • passing gas

For Healthcare Professionals

Applies to dextromethorphan / quinidine: oral capsule

Nervous system

Nervous system side effects have included drowsiness, dizziness, asthenia, nervousness, and restlessness.[Ref]

Gastrointestinal

Gastrointestinal side effects have included diarrhea, vomiting, flatulence, and abdominal pain.[Ref]

Musculoskeletal

Musculoskeletal side effects have included muscle spasticity and muscle spasms.[Ref]

Respiratory

Respiratory side effects have included cough and respiratory failure.[Ref]

Genitourinary

Genitourinary side effects have included urinary tract infection.[Ref]

General

General side effects have included influenza and increased gamma-glutamyltransferase.[Ref]

Cardiovascular

Cardiovascular side effects have included peripheral edema.[Ref]

References

1. "Product Information. Nuedexta (dextromethorphan-quinidine)." Avanir Pharmaceuticals, Inc, Aliso Viejo, CA.

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