Neupro Side Effects
Generic Name: rotigotine
Note: This document contains side effect information about rotigotine. Some of the dosage forms listed on this page may not apply to the brand name Neupro.
Some side effects of Neupro may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to rotigotine: transdermal patch extended release
Along with its needed effects, rotigotine (the active ingredient contained in Neupro) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking rotigotine:More common
- Burning, itching, redness, skin rash, swelling, or soreness at the application site
- swelling of the hands, ankles, feet, or lower legs
- Bladder pain
- bloody or cloudy urine
- blurred vision or other changes in vision
- difficult, burning, or painful urination
- frequent urge to urinate
- lower back or side pain
- pounding in the ears
- seeing, hearing, or feeling things that are not there
- slow or fast heartbeat
Get emergency help immediately if any of the following symptoms of overdose occur while taking rotigotine:Symptoms of overdose
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness
Some side effects of rotigotine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Sleepiness or unusual drowsiness
- Acid or sour stomach
- difficulty having a bowel movement (stool)
- difficulty with moving
- dreaming abnormal
- dry mouth
- feeling of constant movement of self or surroundings
- loss of appetite
- muscle pain or stiffness
- pain in the joints
- sensation of spinning
- stomach discomfort, upset, or pain
- trouble sleeping
- unable to sleep
- weight loss
For Healthcare Professionals
Applies to rotigotine: transdermal film extended release
Cardiovascular side effects have included increased heart rate (9%), orthostatic hypotension (5% to 22%), increased blood pressure (4% to 9%), chest pain (greater than 2%), extremity edema (2% or greater), hypertension (2% or greater), syncope (1%), cardiac failure (0.1% to 1%), AV block (0.1% to 1%), bundle branch block (0.1% to 1%), atrial fibrillation (0.1% to 1%), ventricular arrhythmia (less than 0.1%), and ventricular tachycardia (less than 0.1%).
Gastrointestinal side effects have included nausea (2% to 5% or greater), vomiting (2% to 5% or greater), constipation (2% or greater), dyspepsia (2% or greater), and anorexia (2% or greater).
Nervous system side effects have included somnolence (5% or greater), insomnia (5% or greater), dizziness (2% to 5% or greater), headache (2% to 5% or greater), tremor (greater than 2%), increased sweating (2% or greater), vertigo (2% or greater), dry mouth (2% or greater), paresthesia (1%), confusion (1%), ataxia (1%), abnormal gait (1%), neuralgia (1%), hypesthesia (1%), hypertonia (1%), increased saliva (0.1% to 1%), increased appetite (0.1% to 1%), impotence (0.1% to 1%), flushing (0.1% to 1%), and convulsions (less than 0.1%). Dyskinesia has been reported (0.5%).
Musculoskeletal side effects have included back pain (2% or greater), arthralgia (2% or greater), and myalgia.
Respiratory side effects have included cough (greater than 2%), respiratory tract infection (greater than 2%), rhinitis (greater than 2%), and sinusitis (2% or greater).
Ocular side effects have included abnormal vision (2% or greater) and photopsia (0.1% to 1%).
Genitourinary side effects have included micturition frequency (greater than 2%), urinary tract infection (2% or greater), and urinary incontinence (1%).
Hypersensitivity side effects have included allergic reactions (0.1% to 1%).
Hepatic side effects have included increased gamma-glutamyl transferase (1%).
Metabolic side effects have included weight gain (1%), weight loss, and decreased blood glucose.
Renal side effects have included increased BUN.
Hematological side effects have included thrombocytopenia (0.1% to 1%) and decreased hemoglobin.
Dermatological side effects have included erythematous rash (2% or greater), contact dermatitis (1%), pruritus (1%), and purpura (1%).
Psychiatric side effects have included anxiety (greater than 2%), depression (greater than 2%), somnolence (2% or greater), insomnia (2% or greater), abnormal dreaming (2% or greater), hallucinations (2% or greater), paranoid reaction (0.1% to 1%), and psychosis (0.1% to 1%).
Local side effects have included application site reactions (2% to 5% or greater).
Other side effects have included abdominal pain (greater than 2%), influenza like symptoms (greater than 2%), asthenia (greater than 2%), fall (greater than 2%), fatigue (2% or greater), accident NOS (2% or greater), leg pain (1%), malaise (1%), fever (1%), rigors (0.1% to 1%), hot flushes (0.1% to 1%), hyperesthesia (0.1% to 1%), and tinnitus (0.1% to 1%).
More about Neupro (rotigotine)
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