Neupro Side Effects

Please note - some side effects for Neupro may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Side Effects of Neupro - for the Consumer

Neupro

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Neupro:

Back or joint pain; constipation; decreased appetite; dizziness; drowsiness; dry mouth; fatigue; headache; increased sweating; minor redness, swelling, or itching at the application site; nausea; trouble sleeping; upset stomach; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal dreams; chest pain; confusion; difficult or decreased urination; fainting; fast, slow, or irregular heartbeat; fever; hallucinations; leg pain; loss of coordination; numbness or tingling of the skin; rigid muscles; sudden, severe drowsiness or falling asleep during normal daily activities; swelling of the arms or legs; trouble swallowing; unusual tiredness or weakness; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

Side Effects by Body System - for Healthcare Professionals

Cardiovascular

Cardiovascular side effects have included increased heart rate (9%), orthostatic hypotension (5% to 22%), increased blood pressure (4% to 9%), chest pain (greater than 2%), extremity edema (2% or greater), hypertension (2% or greater), syncope (1%), cardiac failure (0.1% to 1%), AV block (0.1% to 1%), bundle branch block (0.1% to 1%), atrial fibrillation (0.1% to 1%), ventricular arrhythmia (less than 0.1%), and ventricular tachycardia (less than 0.1%).

Gastrointestinal

Gastrointestinal side effects have included nausea (2% to 5% or greater), vomiting (2% to 5% or greater), constipation (2% or greater), dyspepsia (2% or greater), and anorexia (2% or greater).

Nervous system

Nervous system side effects have included somnolence (5% or greater), insomnia (5% or greater), dizziness (2% to 5% or greater), headache (2% to 5% or greater), tremor (greater than 2%), increased sweating (2% or greater), vertigo (2% or greater), dry mouth (2% or greater), paresthesia (1%), confusion (1%), ataxia (1%), abnormal gait (1%), neuralgia (1%), hypesthesia (1%), hypertonia (1%), increased saliva (0.1% to 1%), increased appetite (0.1% to 1%), impotence (0.1% to 1%), flushing (0.1% to 1%), and convulsions (less than 0.1%). Dyskinesia has been reported (0.5%).

Musculoskeletal

Musculoskeletal side effects have included back pain (2% or greater), arthralgia (2% or greater), and myalgia.

Respiratory

Respiratory side effects have included cough (greater than 2%), respiratory tract infection (greater than 2%), rhinitis (greater than 2%), and sinusitis (2% or greater).

Ocular

Ocular side effects have included abnormal vision (2% or greater) and photopsia (0.1% to 1%).

Genitourinary

Genitourinary side effects have included micturition frequency (greater than 2%), urinary tract infection (2% or greater), and urinary incontinence (1%).

Hypersensitivity

Hypersensitivity side effects have included allergic reactions (0.1% to 1%).

Hepatic

Hepatic side effects have included increased gamma-glutamyl transferase (1%).

Metabolic

Metabolic side effects have included weight gain (1%), weight loss, and decreased blood glucose.

Renal

Renal side effects have included increased BUN.

Hematologic

Hematological side effects have included thrombocytopenia (0.1% to 1%) and decreased hemoglobin.

Dermatologic

Dermatological side effects have included erythematous rash (2% or greater), contact dermatitis (1%), pruritus (1%), and purpura (1%).

Psychiatric

Psychiatric side effects have included anxiety (greater than 2%), depression (greater than 2%), somnolence (2% or greater), insomnia (2% or greater), abnormal dreaming (2% or greater), hallucinations (2% or greater), paranoid reaction (0.1% to 1%), and psychosis (0.1% to 1%).

Local

Local side effects have included application site reactions (2% to 5% or greater).

Other

Other side effects have included abdominal pain (greater than 2%), influenza like symptoms (greater than 2%), asthenia (greater than 2%), fall (greater than 2%), fatigue (2% or greater), accident NOS (2% or greater), leg pain (1%), malaise (1%), fever (1%), rigors (0.1% to 1%), hot flushes (0.1% to 1%), hyperesthesia (0.1% to 1%), and tinnitus (0.1% to 1%).

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