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User Reviews for Pramipexole

Also known as: Mirapex, Mirapex ER

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Restless Legs Syndrome 73 reviews 16 medications
   
8.3
Periodic Limb Movement Disorder 3 reviews 13 medications
   
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Summary of Pramipexole reviews 82 reviews 8.1

Reviews for Pramipexole

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Review by Bublez:

User Rating:  
   
10

Mirapex (pramipexole) for Restless Legs Syndrome: Have had RLS since I was 10 years old (now 62 yrs old). In my 20's RLS really started causing me problems. I have had different types of medications, dosages and combinations. My doctor put me on .5 mg Mirapex three times a day. Usually only take it twice, afternoon and bedtime, unless I am having a bad day of RLS. Mirapex has been fantastic for me. If I am very active during the day, I take a pill in the morning. Never experienced side effects. Some evenings the RLS stays active, I get up take a 15 minute hot bath, back to bed, this seems to resolve this problem. Every nerve in my body now becomes unnerved for about 5 minutes 30 minutes after taking Mirapex. My Neurologist said the RLS is problem since I have had RLS for over 50 years.

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April 18, 2015 12:42 AM

Review by hv2miracles (taken for 1 to 6 months):

User Rating:  
   
5.0

Mirapex (pramipexole) for Restless Legs Syndrome: I was taking Clonazepam then my doc suggested Primapexole as it is non-habit forming. It certainly took care of my restless legs but I woke up with headaches and went to sleep with headaches. Indigestion was also a side effect, so much so that I was constantly very bloated and did not feel well for the month I took Primapexole. The positives were that my RSL was non-existent and I did not feel tired in the am. As a matter of fact, I was able to get up 2 hours earlier every day. Don't know why that happened but it was nice to not feel so sleepy in the morning. Now I'm back on Clonazepam and I'm not sure if I'm that happy with it this time around. Is there anything else to try??

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April 15, 2015 10:35 AM

Review by Nicknameisalreadyinuse:

User Rating:  
   
10

For Restless Legs Syndrome: I have taken pramipexole and Requip for restless legs syndrome. Both are equally effective for me. There are other very good side effects that I get. Antidepressant qualities that I didn't need but I actually like. Also the sexual sides have been overwhelmingly positive. I have had no negative sides after the first few days. Oh, and my legs lay there like rocks and shut up instead of having to get up and walk around 3 times before falling asleep.

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February 6, 2015 4:28 PM

Review by Bo's mummy (taken for less than 1 month):

User Rating:  
   
7.0

Mirapex (pramipexole) for Restless Legs Syndrome: I'm writing from the UK! The main difference is that all our medication is free for over 65s and some others. I've been on Co-coda of (apologies, iPad won't let me spell this correctly), Tramadol and Gabapentin. My restlessness has been getting worse and worse for years and a couple of weeks ago I kicked a hole in my bed sheet during the night. So, a few days ago, I saw my GP and he stopped the Tramadol (I'd been tolerating it well) and last night I took my first Mirapex. Oh what a horrible experience! I felt dreadfully ill during the night and when I got up this morning I felt as if I had flu. I was dizzy, sneezy and in a cold sweat. Now I'm not sure whether to continue - maybe the side effects will settle.

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January 31, 2015 7:16 AM

Review by Peacox (taken for 5 to 10 years):

User Rating:  
   
10

For Restless Legs Syndrome: Pramipexole has changed my life! I have suffered with restless legs syndrome since I was about 25 years old and I am now 78. After starting this medication I have been able to get a good, full-nights sleep. As a result of sleeping well, I have a lot more day-time energy. I occasionally have bouts of RLS but with the consent of my doctor, just increasing the dosage for a few days will get me through these episodes. Sometimes I don't increase the dosage during one of these episodes but take a hot bath which helps. When I have been without the meds for a couple of days, not even a hot bath will help. This has been a WONDERFUL medicine for me. It literally has made my life full again.

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January 16, 2015 8:45 PM

Review by Peter Patti Anne:

For Restless Legs Syndrome: Almost immediate nausea which lasted well into the next day. Loss of appetite. Everything tasted off.

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January 16, 2015 4:21 PM

Review by Heather336 (taken for 10 years or more):

User Rating:  
   
10

For Restless Legs Syndrome: I've had restless leg for years now. I started getting it when I was 18 now I'm 40. I tried everything, the 30/500 Co-codomol did work. I did not want to take them long term, my doctor put me on pramipexole and they work great for me.

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January 11, 2015 2:33 AM

Review by wiggleworm (taken for 5 to 10 years):

User Rating:  
   
8.0

Mirapex (pramipexole) for Restless Legs Syndrome: This has been extremely useful in the stopping my restless legs at night. If I happen to stop or run out I'm experiencing the restless legs again. I hate that feeling and have to get up and shake my legs. It is a feeling I simply can't stand!

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December 29, 2014 12:50 PM

Review by jou5703:

User Rating:  
   
10

For Restless Legs Syndrome: I have Restless Legs Syndrome so bad drove me nuts!! Treadmill at 02:00 am to take away the RLS. Pramipexole saved me from going crazy. I can sleep and live a normal life.

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December 12, 2014 7:21 PM

Review by Robert Reger:

User Rating:  
   
1.0

Mirapex (pramipexole) for Restless Legs Syndrome: I have taken this medicine before and it made my Restless Legs Syndrome much worse. For over 25 years I have taken Percocet. I may have to back to that. I read some where that side effects can last for up to a year, I hope not.

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September 2, 2014 3:13 PM

Review by Rip Van Winkle (taken for 2 to 5 years):

User Rating:  
   
10

Mirapex (pramipexole) for Restless Legs Syndrome: I was diagnosed with Restless Legs Syndrome about 4 yrs ago and was prescribed Mirapex. My symptoms were so bad I wouldn't sleep for days and was non functioning due to being sleep deprived. The doctor put me on 0.25mg every evening but my RLS was creeping into daylight hours, so I was prescribed 0.25mg twice a day. That did the trick and it has saved my sanity. I no longer have any symptoms of RLS --and as a side note - I have no side effects either from the medicine.

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July 15, 2014 11:28 PM

Review by RLS Advocate (taken for less than 1 month):

User Rating:  
   
1.0

For Restless Legs Syndrome: Restless Legs Syndrome in a nut-shell: Find your trigger. After a lot of experimentation, I've found that a number of things contribute to my RLS: -fatigue -iron-deficiency (possible other deficiencies) -anxiety -alcohol ... I'm sure there are more. In any case, I did try this medication as sometimes I can't determine the cause. It was awful! It made me restless throughout the night. I completely dried up. Finally, when the medicine started to wear off, I could barely move around from extreme fatigue as though I never slept. Sure it'll make you drowsy, but don't expect a goods nights rest. I've since found that fighting restless legs syndrome is best by fighting the above triggers.

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June 30, 2014 7:38 PM

Review by Ms. P'grass:

User Rating:  
   
10

Mirapex (pramipexole) for Restless Legs Syndrome: Can't live without this medication

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May 25, 2014 6:08 PM

Review by Catlizg (taken for less than 1 month):

User Rating:  
   
10

For Restless Legs Syndrome: I've dealt with 10+ years of restless legs and arms to the point I'd be in tears and have actually fallen out of my king sized bed. After trials of numerous medications (Ambien, Lunesta, leviteracetam, tranquilizers, mega vitamins) and months of little to no sleep I went begging for help to my GP. i was desperate at that point. With nothing else to try he sent me to a neurologist who specialized in sleep disorders and RLS. She started me on melatonin 1 mg at 6 pm, 5 mg at sleep along with pramipexole 0.25 mg in late afternoon if needed and 0.5 mg at 9 PM. WOW. Within one week I was getting far more sleep than I've seen in at least 2 years.

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April 4, 2014 11:37 PM

Review by Mischiefs Mommy (taken for 2 to 5 years):

User Rating:  
   
10

Mirapex (pramipexole) for Restless Legs Syndrome: I absolutely love this! If I don't have it I cannot sleep. And I kick my husband out of bed. So you could say this medicine has saved my marriage.

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January 17, 2014 11:43 PM

Review by KayInPA (taken for 1 to 2 years):

User Rating:  
   
10

Mirapex (pramipexole) for Periodic Limb Movement Disorder: I have been taking Mirapex for a number of years, and it has worked best for me. I take 1 tab during day, 2 in early evenings. I had taken a high does of gabapentin/Neutontin, but some suppliers have a huge pill that was just too difficult for me to take.

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January 11, 2014 6:15 AM

Review by a j l:

User Rating:  
   
9.0

Mirapex (pramipexole) for Restless Legs Syndrome: This is great. No more movements or discomfort at night.

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September 29, 2013 7:20 AM

Review by it's complicated (taken for 1 to 2 years):

User Rating:  
   
9.0

For Restless Legs Syndrome: Started using pramipexole when weaning from zolpidem at sleep clinic. Long term insomnia complicated by shift work/school/age/family history. Pramipexole at 0.125mg/qd worked for about 9 months. Less effective if taken with food. Now, after a year, about 3 X week, first dose insufficient, so I take a second and that works. No side effects in gastrointestinal or balance/reaction time.

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September 16, 2013 2:31 PM

Review by xanti:

User Rating:  
   
1.0

Mirapex (pramipexole) for Parkinson's Disease: I was recently diagnosed with Parkinson's disease. I was started on Mirapex, after 3 weeks of therapy I had to stop due to severe side effects: auditive hallucinations, nausea, peripheral edema, muscle pain, vivid dreams and the worst, difficulty sleeping having the need to get up and move constantly. I'm sure that this is a very good medication but I couldn't tolerate the side effects

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August 30, 2013 3:37 PM

Review by quiltrn:

User Rating:  
   
9.0

Mirapex (pramipexole) for Restless Legs Syndrome: Works great but I get very stuffy for about an hour after I take it.

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June 22, 2013 1:50 PM

Review by sumuji (taken for 1 to 6 months):

User Rating:  
   
7.0

Mirapex (pramipexole) for Restless Legs Syndrome: It takes care of the Restless Legs Syndrome symptoms but also seems to give me insomnia, which kind of defeats the purpose. I can initially go to sleep and get a 3-4 hours but then I'm suddenly wide awake. Requip worked for a while but you have to increase dosage fairly quickly and that causes some bad side effects. I may have to try a 3rd option.

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June 13, 2013 12:21 AM

Review by jdswanberg (taken for 6 months to 1 year):

User Rating:  
   
10

For Restless Legs Syndrome: I had suffered restless legs syndrome periodically for many years. Then, suddenly, I was getting RLS every night. The weird thing, to me, is that I also had the feelings in my arms, but certainly not as frequently as the legs. After weeks of trying to reposition my legs, ignoring it (impossible!), I finally went to my doctor. I took my first dose that night, and haven't had symptoms ever since. I read up on the long-term usage, and am a little concerned about it. I'll cross that bridge if and when I cross it.

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May 16, 2013 9:37 PM

Review by Saro (taken for less than 1 month):

User Rating:  
   
1.0

Mirapex (pramipexole) for Restless Legs Syndrome: Delighted to hear others have benefited by taking Mirapex, I have had very mixed results. It certainly has alleviated my symptoms connected with Restless Legs Syndrome. But the relief came with a price. I became so nauseated that I was up all night, so after three nights I had to stop taking the medicine. I found Percocet the ideal replacement.

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May 2, 2013 2:49 PM

Review by SWS Canadian (taken for 10 years or more):

User Rating:  
   
9.0

Mirapex (pramipexole) for Restless Legs Syndrome: I was diagnosed with Restless Legs Syndrome back in the '90's. I was first prescribed levodopa/carbidopa and it was wonderful at first. However it started losing effectiveness and making me sick during the day at times. Then a new medicine came out- Mirapex and I was put on it at 0.25mg before bedtime. It worked well for several years but had to be upped to 0.5mg. I found that Mirapex controlled my RLS fairly well and I was on it for 12 years! The last year I forced myself to cut back to 0.25mg again and put up with some symptoms. Then, I recently stopped taking it altogether. I have been taking strong vitamin supplements, but they didn't stop the RLS. However, when I started taking Magnesium, Potassium, and Calcium, and bathing in bath salts the RLS has disappeared.

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March 27, 2013 1:29 PM

Review by this works for me. (taken for 1 to 6 months):

User Rating:  
   
9.0

Mirapex (pramipexole) for Restless Legs Syndrome: I started getting Restless Legs Syndrome in 2010, caught me off guard. I was taking Requip, and that worked for awhile, but I found that I was getting leg shaking during the day. Since I sit at a computer all day, this was very annoying and would actually interfere with my job. So I started taking the Requip during the day to alleviate the shaking, that made me very tired. I went to a neurologist, and he changed my script to Mirapex. The 1st night was wonderful, the next full day, I was sleepy. He had put me on 0.5 tabs 3x a day. I found that if I cut a tab into quarters, I could take 1/4 during the day with miminal sleepiness, and 1/2 tab at night when I wanted to sleep real good. So I end up taking the pill just 2x a day.

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March 14, 2013 10:41 AM

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