Skip to main content

Pramipexole User Reviews & Ratings (Page 3)

Brand names: Mirapex ER

Pramipexole has an average rating of 6.7 out of 10 from a total of 233 reviews on Drugs.com. 57% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Pramipexole

  • Anonymous
  • September 20, 2008

Mirapex (pramipexole) for Restless Legs Syndrome "Mirapex has worked like a miracle for me. I can go on long trips again without constant leg "stretching/wiggling/massaging/exercising/deep-knee-bending" to take away the terrible sensations in my legs! I also do not "twitch" and "kick" in bed, like I used too."

10 / 10
Was this helpful?YesNo
54 Report
  • wiggl...
  • Taken for 5 to 10 years
  • December 29, 2014

Mirapex (pramipexole) for Restless Legs Syndrome "This has been extremely useful in the stopping my restless legs at night. If I happen to stop or run out I'm experiencing the restless legs again. I hate that feeling and have to get up and shake my legs. It is a feeling I simply can't stand!"

8 / 10
Was this helpful?YesNo
37 Report
  • Oldve...
  • December 28, 2015

Mirapex (pramipexole) for Restless Legs Syndrome "On requip several yrs when it stopped working. Switched to Mirapex 1 mg and had immediate relief. Now, 6 months later, RLS back for 3 to 4 hours at bedtime. Also some symptoms during day, so sometimes take .5 mgs during day with some relief. No significant side effects."

9 / 10
Was this helpful?YesNo
33 Report

Frequently asked questions

  • Bos...
  • Taken for less than 1 month
  • January 31, 2015

Mirapex (pramipexole) for Restless Legs Syndrome "I'm writing from the UK! The main difference is that all our medication is free for over 65s and some others. I've been on Co-coda of (apologies, iPad won't let me spell this correctly), Tramadol and Gabapentin. My restlessness has been getting worse and worse for years and a couple of weeks ago I kicked a hole in my bed sheet during the night. So, a few days ago, I saw my GP and he stopped the Tramadol (I'd been tolerating it well) and last night I took my first Mirapex. Oh what a horrible experience! I felt dreadfully ill during the night and when I got up this morning I felt as if I had flu. I was dizzy, sneezy and in a cold sweat. Now I'm not sure whether to continue - maybe the side effects will settle."

7 / 10
Was this helpful?YesNo
35 Report
  • longt...
  • September 20, 2011

Mirapex (pramipexole) for Restless Legs Syndrome "Severe restless legs syndrome with Periodic Limb movement for over 45 yrs. Clonazepam worked fine for a long time, then became less effective. Doctor added Mirapex - it worked BUT: I gained 60 lbs in 3 yrs from obsessive eating, charged lot of money to my credit cards due to obsessive spending (both stated side effects) AND fell asleep without warning, mostly at night (twice while driving), so I tapered off. Have lost most of the weight, paying off the bills, but need more than clonazepam."

5 / 10
Was this helpful?YesNo
44 Report

Are you taking this medicine?

  • Bublez
  • April 18, 2015

Mirapex (pramipexole) for Restless Legs Syndrome "Have had RLS since I was 10 years old (now 62 yrs old). In my 20's RLS really started causing me problems. I have had different types of medications, dosages and combinations. My doctor put me on .5 mg Mirapex three times a day. Usually only take it twice, afternoon and bedtime, unless I am having a bad day of RLS. Mirapex has been fantastic for me. If I am very active during the day, I take a pill in the morning. Never experienced side effects. Some evenings the RLS stays active, I get up take a 15 minute hot bath, back to bed, this seems to resolve this problem. Every nerve in my body now becomes unnerved for about 5 minutes 30 minutes after taking Mirapex. My Neurologist said the RLS is problem since I have had RLS for over 50 years."

10 / 10
Was this helpful?YesNo
33 Report
  • Status
  • Taken for 1 to 6 months
  • May 29, 2020

For Restless Legs Syndrome "Completely knocks out my RLS like a charm. My RLS had been getting worse due to my SSRI treatment so my doctor prescribed Pramipexole in a relatively small 0.125 mg dose when needed before bedtime. “When needed” is a tough decision because, from what I’ve read, the drug could take up to 3 hours to kick in. But, for me, I have normally found relief in less than an hour. The problem is that I feel like a zombie the next day. Drowsy, cloudy head, sluggish for most of the day after taking it. I’ve started breaking the tablets in half to take down the dosage even more. It still works but the side effects are still there. I’m currently searching for another path towards RLS relief with a different medication."

7 / 10
Was this helpful?YesNo
17 Report
  • John
  • Taken for 10 years or more
  • June 18, 2018

Mirapex (pramipexole) for Periodic Limb Movement Disorder "I have had RLS for approximately 20 years. I have been taking Mirapex but only in the evenings before I went to bed. Part of what I attributed to RLS was in fact PLMD. During a sleep study for sleep apnea I kicked an average of 96 times an hour. My RLS remained under control by taking it in the evenings but my PLMD has gotten much worse to the point that I cannot even close my eyes and rest during the day without my legs kicking. I now have to take Mirapex at mid day , again in the late afternoon and then before bedtime. Without it I would be a crazy person."

10 / 10
Was this helpful?YesNo
23 Report
  • Franky...
  • December 29, 2012

Mirapex (pramipexole) for Periodic Limb Movement Disorder "I had terrible side effects on this medicine. I was over active and couldn't stop making things, knitting, etc. all through the night . I couldn't sleep and my balance was off. I fell in the shower and hurt my neck. This was a terrible time for me."

1 / 10
Was this helpful?YesNo
36 Report
  • Cookr...
  • Taken for 5 to 10 years
  • April 12, 2020

For Restless Legs Syndrome "I have taken pramipexole for RLS for at least seven years. It is still very effective for treating my RLS. I am taking 0.63 mg per day. No noticeable side-effects. Without it I get no sleep at all as my legs are moving constantly all night."

10 / 10
Was this helpful?YesNo
16 Report
  • hv2mi...
  • Taken for 1 to 6 months
  • April 15, 2015

Mirapex (pramipexole) for Restless Legs Syndrome "I was taking Clonazepam then my doc suggested Primapexole as it is non-habit forming. It certainly took care of my restless legs but I woke up with headaches and went to sleep with headaches. Indigestion was also a side effect, so much so that I was constantly very bloated and did not feel well for the month I took Primapexole. The positives were that my RSL was non-existent and I did not feel tired in the am. As a matter of fact, I was able to get up 2 hours earlier every day. Don't know why that happened but it was nice to not feel so sleepy in the morning. Now I'm back on Clonazepam and I'm not sure if I'm that happy with it this time around. Is there anything else to try??"

5 / 10
Was this helpful?YesNo
29 Report
  • Anonymous
  • January 1, 2011

Mirapex (pramipexole) for Restless Legs Syndrome "I've had restless leg syndrome for about 15 years and have tried several medications. Gabapentin worked most nights, but left me practically catatonic the next day. Klonopin did nothing to help my symptoms. Requip made me feel like I was going insane, and really scared me. I gave Mirapex a high rating because it has completely eliminated all my symptoms. Unfortunately, I have severe nasal congestion as a side effect which also keeps me up all night. If I don't take it, I can breathe, but my legs are jumping and jerking all night. If I do take it, my nose feels like it's filled with cement. Either way I can't sleep. I guess it's back to the doctor to try something else."

9 / 10
Was this helpful?YesNo
38 Report
  • Margo...
  • Taken for 1 to 6 months
  • March 18, 2016

Mirapex (pramipexole) for Periodic Limb Movement Disorder "My husband had PLMD and Restless Legs for decades and it continued to get worse. He was given Mirapex and the first night it was if a miracle had happened. It completely stopped all the crazy movements that we both had endured. Life changing."

10 / 10
Was this helpful?YesNo
26 Report
  • gbeagle
  • August 10, 2015

Mirapex (pramipexole) for Restless Legs Syndrome "I have had RLS for 25 years, and within the past two years has gotten much more uncontrollable. Ten years ago I took Requip for awhile, but the drowsiness during the day was a bother, and the RLS wasn't much improved. Last month I started on Mirapex and the relief from RLS was almost immediate. I'm currently taking .250 mg. two hours before bedtime. The only bothersome side effect has been some increased urination urges during the night. I haven't noticed any problems with dizziness but I do have occasional Benign Positional Vertigo anyway, so it certainly isn't any worse. Overall, I would say Mirapex has done the trick."

8 / 10
Was this helpful?YesNo
27 Report
  • ano
  • March 13, 2009

Mirapex (pramipexole) for Restless Legs Syndrome "I take half a pill around supper time so I can sleep. My restless leg syndrome usually kicks up right before bed. I wouldn't be able to sleep without it. It has been wonderful to just go to bed and really rest."

Was this helpful?YesNo
41 Report
  • Anonymous
  • September 16, 2008

Mirapex (pramipexole) for Restless Legs Syndrome "Mirapex is a godsend. Before Mirapex, sleep was non-existant unless I took a sleeping pill. Now I get peaceful nights sleep. The only drawback is, it's expensive and insurance barely covers any of the cost. But I can't live without it."

10 / 10
Was this helpful?YesNo
42 Report
  • wazzup
  • Taken for 2 to 5 years
  • July 4, 2015

Mirapex (pramipexole) for Restless Legs Syndrome "I have had RLS since I went through my last growing spurt at the age of 14. I am now 35 and have tried every over the counter drug, herb and supplement known to man. Nothing helped. I tried Mirapex and though it did not always fully work, it worked sometimes, and if you have RLS you know that sometimes is pretty awesome. I started taking tramadol for back pain and for the last year me RLS is completely gone. The only problem is that tramadol was like taking cold medicine and down right horrible most days and the withdrawal can be life-threatening in my opinion. As we all know, any opiate taken right before bed completely cures RLS. But if you stop taking it, your RLS will be 100 times worse, of course the time spent sleeping is worth it!"

6 / 10
Was this helpful?YesNo
27 Report
  • Anonymous
  • September 1, 2011

Mirapex (pramipexole) for Restless Legs Syndrome "I have had restless leg syndrome all my life. I can remember when I was about 5 or 6 telling my mom my feet tickle...didn't know how else to explain it at that age. Today I am 39 yrs old and am only alive because of Mirapex. My RLS has become so severe that without this medication I would not sleep. One time I was without my medication and was up for 3 days straight. Ended up in the emergency room many times when I didn't have any medication just to get some form of relief. I currently take Mirapex 1mg at night, but sometimes will have to take a half during the day. My RLS will bother me mid afternoon at times and when it's really bad will go into my hands and forearms. I am eternally grateful for Mirapex despite the side effects of nausea, tired and weak."

10 / 10
Was this helpful?YesNo
35 Report
  • Catlizg
  • Taken for less than 1 month
  • April 4, 2014

For Restless Legs Syndrome "I've dealt with 10+ years of restless legs and arms to the point I'd be in tears and have actually fallen out of my king sized bed. After trials of numerous medications (Ambien, Lunesta, leviteracetam, tranquilizers, mega vitamins) and months of little to no sleep I went begging for help to my GP. i was desperate at that point. With nothing else to try he sent me to a neurologist who specialized in sleep disorders and RLS. She started me on melatonin 1 mg at 6 pm, 5 mg at sleep along with pramipexole 0.25 mg in late afternoon if needed and 0.5 mg at 9 PM. WOW. Within one week I was getting far more sleep than I've seen in at least 2 years."

10 / 10
Was this helpful?YesNo
29 Report
  • kasia...
  • March 17, 2009

Mirapex (pramipexole) for Restless Legs Syndrome "I took Mirapex for moderate RLS for about a year and it worked like a charm. Then I began to develop side effects bad enough to force me to quit. Eventually, within 30 minutes of taking Mirapex at night I would experience severe nausea and vomiting that would last for hours."

5 / 10
Was this helpful?YesNo
38 Report
  • Mr Ex...
  • Taken for 6 months to 1 year
  • January 13, 2020

For Restless Legs Syndrome "I was on Pramipexole for about eight months with no side effects. However, in the beginning I had two or three nights where the RLS seemed to be waning but it soon came back. My Dr increased the dosage twice but the RSL did not get any better. After eight months with no results, I gradually came off the medication . As soon as I stopped it, my RSL came back with a vengeance. I'm now getting it in the mornings, which I never did before. I'm getting it in my hands as well as my legs and feet, which I very rarely got before. It is ten times worse in intensity , and I now have difficulty getting and maintaining an erection, something which I had no problem doing until I stopped the Pramipexole."

1 / 10
Was this helpful?YesNo
15 Report
  • Anonymous
  • September 6, 2011

Mirapex (pramipexole) for Restless Legs Syndrome "Truly a God send. You don't feel like you've run a marathon all night. Other comments are true about running out of a prescription, or not taking it for a few days. You can tell! I just have one question --- if it feels like you've run a marathon all night, how come you don't wake up skinnier?"

10 / 10
Was this helpful?YesNo
33 Report
  • H6HSW
  • September 3, 2017

For Restless Legs Syndrome "I was prescribed this drug in April 2008 by a consultant neuro for RLS. I WAS NOT TOLD OF THE SIDE EFFECTS AS MY MEDS CAME IN BLISTER PACKS !!! I spent £130,000 due to compulsive shopping (yes, it is a side effect)! I was forced to set up an Individual Voluntary Arrangement (IVA) it ruined my life I was a different person it destroyed me. In the end my marriage fell apart , I lost my home £300,000.00, And my self respect. PLEASE please be very carefull on taking this drug as I know I'm not the only person to suffer."

Was this helpful?YesNo
20 Report
  • Robert...
  • September 2, 2014

Mirapex (pramipexole) for Restless Legs Syndrome "I have taken this medicine before and it made my Restless Legs Syndrome much worse. For over 25 years I have taken Percocet. I may have to back to that. I read some where that side effects can last for up to a year, I hope not."

1 / 10
Was this helpful?YesNo
26 Report
  • MJCRH
  • March 18, 2010

Mirapex (pramipexole) for Restless Legs Syndrome "I have been taking Mirapex for a number of years for RLS. I originally took 0.125mg once a day. After a few years it was increased to 0.125mg twice a day as my symptoms were rather severe. I have remained at the same dosage since then and have developed no side effects to the medication. I would seldom be able to sleep except for this medication."

10 / 10
Was this helpful?YesNo
34 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.