Locoid Lipocream Side Effects
Generic Name: hydrocortisone topical
Note: This page contains information about the side effects of hydrocortisone topical. Some of the dosage forms included on this document may not apply to the brand name Locoid Lipocream.
Not all side effects for Locoid Lipocream may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to hydrocortisone topical: topical application cream, topical application ointment
Other dosage forms:
- topical application cream
- topical application cream, topical application lotion, topical application ointment, topical application solution
- topical application cream, topical application foam, topical application gel/jelly, topical application kit, topical application liquid, topical application lotion, topical application ointment, topical application pad, topical application paste, topical application solution, topical application spray, topical application stick
In addition to its needed effects, some unwanted effects may be caused by hydrocortisone topical (the active ingredient contained in Locoid Lipocream). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking hydrocortisone topical:More common
- Skin rash, encrusted, scaly, and oozing
- Burning, itching, redness, skin rash, swelling, or soreness at the application site
- cough or hoarseness
- dry skin
- fever or chills
- itching in the genital or other skin areas
- lower back or side pain
- painful or difficult urination
- rash with flat lesions or small raised lesions on the skin
- skin irritation
- Blistering, burning, crusting, dryness, or flaking of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
- redness and scaling around the mouth
- thinning of the skin with easy bruising, especially when used on facial or intertriginous areas
Some of the side effects that can occur with hydrocortisone topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Less common
- loss of appetite
- nausea or vomiting
- passing of gas
- stomach pain, fullness, or discomfort
- Acne or pimples
- burning and itching of the skin with pinhead-sized red blisters
- burning, itching, and pain in hairy areas, or pus at the root of the hair
- increased hair growth on the forehead, back, arms, and legs
- lightening of normal skin color
- lightening of treated areas of dark skin
- reddish purple lines on the arms, face, legs, trunk, or groin
- softening of the skin
For Healthcare Professionals
Applies to hydrocortisone topical: compounding powder, rectal cream with applicator, rectal foam, rectal ointment, rectal solution, rectal suppository, topical cream, topical gel, topical kit, topical lotion, topical ointment, topical pad, topical paste, topical solution, topical spray, topical stick
Endocrine side effects of topical corticosteroids are rare. Glucose intolerance and hyperglycemia may be induced by corticosteroids. These drugs can rarely suppress the hypothalamic-pituitary-adrenal axis. This suppression is more likely when higher potency topical steroids are used over extensive areas and when occlusive dressings are used.[Ref]
Local adverse effects of hydrocortisone application may commonly include burning, itching, or irritation, especially if applied to denuded skin or with occlusive dressings. Long-term use of topical corticosteroids may result in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis is occasionally reported.[Ref]
Skin on the face, axillae, and groin appear to be most susceptible to the adverse, long-term effects of topical steroids.
Topical corticosteroid use may inhibit local immune response rendering the skin more susceptible to infections. Folliculitis has occasionally been reported.
Perioral dermatitis or rosacea-like dermatitis has occurred in patients treated with potent topical corticosteroids who are of seborrheic skin type. This condition may flare temporarily upon discontinuation of topical steroids, prompting patients to continue their use. If topical corticosteroids are discontinued, this flare and the initial dermatitis generally resolves over a few weeks.[Ref]
Gastrointestinal side effects of rectally administered hydrocortisone include diarrhea, cramps, flatulence, rectal irritation, and rectal bleeding.[Ref]
Musculoskeletal side effects from rectal administration may include muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis of femoral and humeral heads, and pathologic fracture of long bones.[Ref]
1. "Product Information. Pandel (hydrocortisone topical)." Savage Laboratories, Melville, NY.
2. Patel L, Clayton PE, Addison GM, Price DA, David TJ "Adrenal function following topical steroid treatment in children with atopic dermatitis." Br J Dermatol 132 (1995): 950-5
3. Jorizzo J, Levy M, Lucky A, Shavin J, Goldberg G, Dunlap F, Hinds A, Strelka L, Baker M, Tuley M, Czernielewski JM "Multicenter trial for long-term safety and efficacy comparison of 0.05% desonide and 1% hydrocortisone ointments in the treatment of atopic dermatitis in pediatric patients." J Am Acad Dermatol 33 (1995): 74-7
4. Lima JJ, Giller J, Mackichan JJ, Jusko WJ "Bioavailability of hydrocortisone retention enemas in normal subjects." Am J Gastroenterol 73 (1980): 232-7
More about Locoid Lipocream (hydrocortisone topical)
- Locoid Lipocream
- Locoid Lipocream (Advanced Reading)
- Locoid Lipocream Topical application (Advanced Reading)
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