Liraglutide Side Effects

Some side effects of liraglutide may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to liraglutide: subcutaneous solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking liraglutide: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• swelling or a lump in your throat area;

• hoarse voice, trouble swallowing, feeling short of breath;

• urinating less than usual or not at all;

• weakness, confusion, increased thirst, loss of appetite, pounding heartbeats or fluttering in your chest;

• swelling, weight gain, feeling short of breath;

• pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate; or

• signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), mouth sores, unusual weakness.

Less serious side effects of liraglutide may include:

• headache, dizziness;

• upset stomach, loss of appetite;

• nausea, vomiting;

• diarrhea, constipation;

• cold symptoms such as stuffy nose, sneezing, sinus pain, sore throat;

• back pain;

• tired feeling;

• mild skin rash; or

• redness or rash where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to liraglutide: subcutaneous solution

Gastrointestinal

Gastrointestinal side effects have included nausea, diarrhea, vomiting, constipation, abdominal pain, decreased appetite, anorexia, dyspepsia, and pancreatitis.

Metabolic

Metabolic side effects have included hypoglycemia, especially when combined with a sulfonylurea. Postmarketing side effects have included dehydration from nausea, vomiting and diarrhea.

Nervous system

Nervous system side effects have included headache and dizziness.

Respiratory

Respiratory side effects have included nasopharyngitis, upper respiratory tract infection, and sinusitis.

General

General side effects have included influenza and fatigue.

Cardiovascular

Cardiovascular side effects have included hypertension.

Genitourinary

Genitourinary side effects have included urinary tract infection.

Musculoskeletal

Musculoskeletal side effects have included back pain.

Local

Local side effects have included injection site rash and erythema.

Immunologic

Immunologic side effects have included urticaria and angioedema.

Hypersensitivity

Hypersensitivity side effects reported postmarketing have included angioedema and anaphylactic reactions, rash and pruritus.

Renal

Postmarketing side effects have included increased serum creatinine, acute renal failure or worsening of chronic renal failure, sometimes requiring hemodialysis.

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