Liraglutide Side Effects

Not all side effects for liraglutide may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to liraglutide: subcutaneous solution

In addition to its needed effects, some unwanted effects may be caused by liraglutide. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking liraglutide:

More common
  • Bladder pain
  • bloody or cloudy urine
  • cough or hoarseness
  • diarrhea
  • difficult, burning, or painful urination
  • fever or chills
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • runny nose
  • shivering
  • sore throat
  • sweating
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting
Less common
  • Blurred vision
  • dizziness
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
Rare
  • Anxiety
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • depression
  • hives or welts
  • increased hunger
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • nightmares
  • redness of the skin
  • seizures
  • shakiness
  • skin rash
  • slurred speech
Incidence not known
  • Agitation
  • confusion
  • decreased urine output
  • depression
  • difficulty with swallowing
  • hostility
  • irritability
  • lethargy
  • muscle twitching
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid weight gain
  • shortness of breath
  • stupor
  • swelling of the face, ankles, or hands
  • tightness in the chest
  • wheezing

Some of the side effects that can occur with liraglutide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Abdominal or stomach cramps, discomfort, or pain
  • acid or sour stomach
  • back pain
  • belching
  • body aches or pain
  • constipation
  • decreased appetite
  • difficulty with breathing
  • heartburn
  • indigestion
  • loss of voice
  • nasal congestion
  • pain or tenderness around the eyes and cheekbones
  • sneezing
  • stuffy nose
  • swollen mouth and tongue
  • unpleasant taste
  • urge to have bowel movement
  • weight loss
Less common
  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For Healthcare Professionals

Applies to liraglutide: subcutaneous solution

Gastrointestinal

Gastrointestinal side effects have included nausea, diarrhea, vomiting, constipation, abdominal pain, decreased appetite, anorexia, dyspepsia, and pancreatitis.

Metabolic

Metabolic side effects have included hypoglycemia, especially when combined with a sulfonylurea. Postmarketing side effects have included dehydration from nausea, vomiting and diarrhea.

Nervous system

Nervous system side effects have included headache and dizziness.

Respiratory

Respiratory side effects have included nasopharyngitis, upper respiratory tract infection, and sinusitis.

General

General side effects have included influenza and fatigue.

Cardiovascular

Cardiovascular side effects have included hypertension.

Genitourinary

Genitourinary side effects have included urinary tract infection.

Musculoskeletal

Musculoskeletal side effects have included back pain.

Local

Local side effects have included injection site rash and erythema.

Immunologic

Immunologic side effects have included urticaria and angioedema.

Hypersensitivity

Hypersensitivity side effects reported postmarketing have included angioedema and anaphylactic reactions, rash and pruritus.

Renal

Postmarketing side effects have included increased serum creatinine, acute renal failure or worsening of chronic renal failure, sometimes requiring hemodialysis.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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