Isopto Homatropine Side Effects

Please note - some side effects for Isopto Homatropine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Isopto Homatropine - for the Consumer

Isopto Homatropine Drops

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Isopto Homatropine Drops:

Blurred vision; eye itching, burning, or stinging; irritation at the application site.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; dry mouth; eye pain; fever; flushing or dryness of the skin; irregular or rapid heartbeat; unsteadiness on your feet.

Side Effects by Body System

Ocular

Ocular side effects have included transient stinging and burning, eye irritation, and increased sensitivity to light. Prolonged use may produce local irritation characterized by follicular conjunctivitis, vascular congestion, edema, exudate and an eczematoid dermatitis.

Gastrointestinal

Gastrointestinal side effects have included thirst and dry mouth.

Nervous system

Nervous system effects due to chronic use of the drug can lead to a confusional state characterized by delirium, agitation, and rarely coma. This state is associated with use in the pediatric and geriatric age groups.

The specific antidote for this systemic anticholinergic syndrome is injectable physostigmine salicylate.

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