Isopto Homatropine Side Effects

Generic name: homatropine ophthalmic

Note: This document contains side effect information about homatropine ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Isopto Homatropine.

Some side effects of Isopto Homatropine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to homatropine ophthalmic: ophthalmic solution

If you experience any of the following serious side effects, stop using homatropine ophthalmic (the active ingredient contained in Isopto Homatropine) and seek emergency medical attention:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• an irregular or fast heart rate;

• hallucinations or unusual behavior (especially in children); or

• a swollen or distended stomach (in infants).

Other, less serious side effects may be more likely to occur. Continue to use homatropine ophthalmic and talk to your doctor if you experience

• blurred vision,

• sensitivity to sunlight,

• stinging and burning, or

• swelling of the eyelids.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For Healthcare Professionals

Applies to homatropine ophthalmic: compounding powder, ophthalmic solution

Ocular

Ocular side effects have included transient stinging and burning, eye irritation, and increased sensitivity to light. Prolonged use may produce local irritation characterized by follicular conjunctivitis, vascular congestion, edema, exudate and an eczematoid dermatitis.

Gastrointestinal

Gastrointestinal side effects have included thirst and dry mouth.

Nervous system

Nervous system effects due to chronic use of the drug can lead to a confusional state characterized by delirium, agitation, and rarely coma. This state is associated with use in the pediatric and geriatric age groups.

The specific antidote for this systemic anticholinergic syndrome is injectable physostigmine salicylate.

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