Ioversol Side Effects
Not all side effects for ioversol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to ioversol: injectable solution
Get emergency medical help if you have any of these signs of an allergic reaction while taking ioversol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some of the side effects of ioversol can occur up to 24 hours after you have received the medication.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
slow heart rate;
swelling, rapid weight gain, little or no urinating;
wheezing or trouble breathing;
heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; or
signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.
Common side effects may include:
warmth or pain when the medicine is injected;
confusion, dizziness, spinning sensation;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to ioversol: injectable solution
Regardless of the contrast medium employed, the overall incidence of serious adverse reaction is higher with coronary arteriography than with other procedures. Cardiac decompensation, serious arrhythmias, myocardial ischemia, or myocardial infarction may occur during coronary arteriography and left ventriculography.[Ref]
Cardiovascular side effects including angina pectoris, hypotension, blood pressure fluctuation, arterial spasm, bradycardia, conduction defect, false aneurysm, hypertension, transient arrhythmia, and vascular trauma have been reported in patients receiving ioversol. Serious, life-threatening, and fatal reactions, angioneurotic edema, peripheral edema, vasodilation, thrombosis, and rarely thrombophlebitis, disseminated intravascular coagulation, and shock have been associated with the administration of iodine-containing contrast media.[Ref]
Respiratory side effects including laryngeal edema, pulmonary edema, sneezing, congestion, coughing, shortness of breath, and hypoxia have been reported. Choking, dyspnea, wheezing (which may be an initial manifestation of more severe and infrequent reactions including asthmatic attack), laryngospasm, bronchospasm, apnea, and cyanosis have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.[Ref]
Gastrointestinal side effects including nausea, vomiting, and dry mouth have been reported.[Ref]
Nervous system side effects including headache, cerebral infarct, vertigo, lightheadedness, visual hallucination, vasovagal reaction disorientation, paresthesia, dysphasia, muscle spasm, and syncope have been reported with the use of ioversol. Convulsions, aphasia, paralysis, coma, and death have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.[Ref]
Ocular side effects including blurred vision have been reported with the use of ioversol. Visual field losses which are usually transient but may be permanent have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.
Dermatologic side effects including periorbital edema, urticaria, pruritus, facial edema, flush, and erythema have been reported. Maculopapular rash, erythema, conjunctival symptoms, ecchymosis, and tissue necrosis have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.[Ref]
Local side effects including extravasation have been reported.[Ref]
Hematologic side effects including hematoma have been reported.[Ref]
General side effects including shaking chills, general pain, and fever have been reported with the use of ioversol. Hyperthermia has been reported with the use of other contrast agents and is possible with any water soluble, iodinated contrast agent.[Ref]
Other side effects including bad taste have been reported.[Ref]
Renal side effects including renal colic, urinary retention, and polyuria have been reported with the use of ioversol. Temporary anuria and other nephropathies have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.[Ref]
1. "Product Information. Optiray 350 (ioversol)." Mallinckrodt Medical Inc, St. Louis, MO.
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