Ioversol Side Effects
It is possible that some side effects of ioversol may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to ioversol: injectable solution
Some of the side effects of ioversol can occur up to 24 hours after you have received the medication.
Get emergency medical help if you have any of these signs of an allergic reaction while taking ioversol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
urinating less than usual or not at all;
severe muscle pain or weakness;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
feeling light-headed, fainting;
wheezing, trouble breathing;
fast or slow heartbeat;
easy bruising, unusual bleeding, or skin changes; or
swelling of your hands, ankles, or feet.
Other less serious side effects are more likely to occur, such as:
fever, warmth, or pain;
skin rash or redness;
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
For Healthcare Professionals
Applies to ioversol: injectable solution
Regardless of the contrast medium employed, the overall incidence of serious adverse reaction is higher with coronary arteriography than with other procedures. Cardiac decompensation, serious arrhythmias, myocardial ischemia, or myocardial infarction may occur during coronary arteriography and left ventriculography.
Cardiovascular side effects including angina pectoris, hypotension, blood pressure fluctuation, arterial spasm, bradycardia, conduction defect, false aneurysm, hypertension, transient arrhythmia, and vascular trauma have been reported in patients receiving ioversol. Serious, life-threatening, and fatal reactions, angioneurotic edema, peripheral edema, vasodilation, thrombosis, and rarely thrombophlebitis, disseminated intravascular coagulation, and shock have been associated with the administration of iodine-containing contrast media.
Respiratory side effects including laryngeal edema, pulmonary edema, sneezing, congestion, coughing, shortness of breath, and hypoxia have been reported. Choking, dyspnea, wheezing (which may be an initial manifestation of more severe and infrequent reactions including asthmatic attack), laryngospasm, bronchospasm, apnea, and cyanosis have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.
Gastrointestinal side effects including nausea, vomiting, and dry mouth have been reported.
Nervous system side effects including headache, cerebral infarct, vertigo, lightheadedness, visual hallucination, vasovagal reaction disorientation, paresthesia, dysphasia, muscle spasm, and syncope have been reported with the use of ioversol. Convulsions, aphasia, paralysis, coma, and death have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.
Ocular side effects including blurred vision have been reported with the use of ioversol. Visual field losses which are usually transient but may be permanent have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.
Dermatologic side effects including periorbital edema, urticaria, pruritus, facial edema, flush, and erythema have been reported. Maculopapular rash, erythema, conjunctival symptoms, ecchymosis, and tissue necrosis have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.
Local side effects including extravasation have been reported.
Hematologic side effects including hematoma have been reported.
General side effects including shaking chills, general pain, and fever have been reported with the use of ioversol. Hyperthermia has been reported with the use of other contrast agents and is possible with any water soluble, iodinated contrast agent.
Other side effects including bad taste have been reported.
Renal side effects including renal colic, urinary retention, and polyuria have been reported with the use of ioversol. Temporary anuria and other nephropathies have been reported with the use of other contrast agents and are possible with any water soluble, iodinated contrast agent.
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