Interferon gamma-1b Side Effects
Brand Names: Actimmune
Please note - some side effects for Interferon gamma-1b may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
Side Effects of Interferon gamma-1b - for the Consumer
Interferon Gamma-1B
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Interferon Gamma-1B:
Seek medical attention right away if any of these SEVERE side effects occur when using Interferon Gamma-1B:Diarrhea; fatigue; flu-like symptoms (eg, low-grade fever, chills, general body discomfort); headache; joint pain; muscle pain; nausea; pain, redness, or swelling at the injection site; tiredness; vomiting; weakness.
TopSevere allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; confusion; dizziness; fainting; fast or irregular heartbeat; high or persistent fever; mood or mental changes; seizures; signs of infection (eg, chills, persistent sore throat); stomach pain; trouble walking; unusual bruising or bleeding; yellowing of the eyes or skin.
Side Effects by Body System
General
General flu-like side effects have been reported most frequently. These have included fever (52%), headache (33%), chills (14%), fatigue (14%), myalgia (6%), and arthralgia (2%). Chest discomfort has been reported.
Gastrointestinal
Gastrointestinal side effects have been reported frequently. These have included diarrhea (14%), vomiting (13%), and nausea (10%). Gastrointestinal bleeding has been reported rarely.
Dermatologic
Dermatologic side effects have included rash (17%).
Local
Local side effects have included erythema or tenderness at the site of injection (14%).
Cardiovascular
Cardiovascular side effects have been reported rarely. These have included hypotension, syncope, tachyarrhythmia, heart block, heart failure, and myocardial infarction.
Nervous system
Nervous system side effects have been reported rarely. These have included confusion, disorientation, gait disturbance, Parkinsonian symptoms, seizure, hallucinations, and transient ischemic attacks.
Respiratory
Respiratory side effects have included tachypnea, bronchospasm, and interstitial pneumonitis.
Hematologic
Hematologic side effects have been reported rarely. These have included deep venous thrombosis and pulmonary embolism.
Renal
Renal side effects have included renal insufficiency which was reversible.
Metabolic
Metabolic side effects have included hyponatremia, hyperglycemia, and hypertriglyceridemia.
Immunologic
Immunologic side effects have included increased autoantibodies and lupus-like syndrome.
TopMore resources:
Actimmune - Includes detailed dosage instructions.
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