Interferon gamma-1b Side Effects
Some side effects of interferon gamma-1b may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to interferon gamma-1b: solution
Along with its needed effects, interferon gamma-1b may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking interferon gamma-1b:Rare
- Black, tarry stools
- blood in urine or stools
- cough or hoarseness
- loss of balance control
- lower back or side pain
- mask-like face
- painful or difficult urination
- pinpoint red spots on skin
- shuffling walk
- stiffness of arms or legs
- trembling and shaking of hands and fingers
- trouble in speaking or swallowing
- trouble in thinking or concentrating
- trouble in walking
- unusual bleeding or bruising
Some side effects of interferon gamma-1b may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Aching muscles
- fever and chills
- general feeling of discomfort or illness
- nausea or vomiting
- skin rash
- unusual tiredness
- Back pain
- joint pain
- loss of appetite
- weight loss
For Healthcare Professionals
Applies to interferon gamma-1b: subcutaneous solution
General flu-like side effects have been reported most frequently. These have included fever (52%), headache (33%), chills (14%), fatigue (14%), myalgia (6%), and arthralgia (2%). Chest discomfort has been reported.
Gastrointestinal side effects have been reported frequently. These have included diarrhea (14%), vomiting (13%), and nausea (10%). Gastrointestinal bleeding has been reported rarely.
Dermatologic side effects have included rash (17%).
Local side effects have included erythema or tenderness at the site of injection (14%).
Cardiovascular side effects have been reported rarely. These have included hypotension, syncope, tachyarrhythmia, heart block, heart failure, and myocardial infarction.
Nervous system side effects have been reported rarely. These have included confusion, disorientation, gait disturbance, Parkinsonian symptoms, seizure, hallucinations, and transient ischemic attacks.
Respiratory side effects have included tachypnea, bronchospasm, and interstitial pneumonitis.
Hematologic side effects have been reported rarely. These have included deep venous thrombosis and pulmonary embolism.
Renal side effects have included renal insufficiency which was reversible.
Metabolic side effects have included hyponatremia, hyperglycemia, and hypertriglyceridemia.
Immunologic side effects have included increased autoantibodies and lupus-like syndrome.
More interferon gamma-1b resources
- interferon gamma-1b Concise Consumer Information (Cerner Multum)
- interferon gamma-1b MedFacts Consumer Leaflet (Wolters Kluwer)
- Interferon Gamma-1b Professional Patient Advice (Wolters Kluwer)
- Actimmune Prescribing Information (FDA)
- Actimmune Monograph (AHFS DI)
- Actimmune Advanced Consumer (Micromedex) - Includes Dosage Information
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