Iloprost Side Effects

It is possible that some side effects of iloprost may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to iloprost: inhalation solution

Along with its needed effects, iloprost may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking iloprost:

Incidence not known
  • Black, tarry stools
  • chest pain
  • cough
  • difficult or labored breathing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • extreme fatigue
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • hives or rash
  • irregular breathing
  • itching
  • noisy breathing
  • pinpoint red spots on the skin
  • swelling of the eyelids, face, lips, fingers, feet, or lower legs
  • tightness in the chest
  • troubled breathing or swallowing
  • unusual bleeding or bruising

Some side effects of iloprost may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Back pain
  • chills
  • cough increased
  • coughing or spitting up blood
  • difficulty opening the mouth
  • feeling of warmth
  • headache
  • lockjaw
  • nausea
  • redness of the face, neck, arms, and occasionally, upper chest
  • sweating
  • trouble sleeping
Less common
  • Change in taste
  • mouth irritation
  • tongue irritation or pain
Incidence not known
  • Nosebleeds
  • stuffy nose

For Healthcare Professionals

Applies to iloprost: inhalation solution

Cardiovascular

Cardiovascular side effects have included congestive heart failure, chest pain, supraventricular tachycardia, peripheral edema, vasodilation (flushing), hypotension, palpitations and syncope.

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting. Postmarketing experience has included diarrhea.

Hepatic

Hepatic side effects have included increased GGT (gamma-glutamyltranspeptidase) and alkaline phosphatase levels.

Musculoskeletal

Musculoskeletal side effects have included muscle cramps, back pain, tongue pain and trismus.

Nervous system

Nervous system side effects have included headache, dizziness and insomnia.

Renal

Renal side effects have included kidney failure.

Respiratory

Respiratory side effects have included hemoptysis, pneumonia, dyspnea and increased cough. Postmarketing experience has included cases of bronchospasm and wheezing, particularly in susceptible patients with hyperreactive airways.

General

General side effects have included flu syndrome. Postmarketing reports have included mouth and tongue irritation and dysgeusia.

Other

Other side effects have included cases of epistaxis and gingival bleeding which have been reported within one month of starting iloprost treatment.

Hypersensitivity

Hypersensitivity side effects have included postmarketing reports of hypersensitivity and rash.

Dermatologic

Dermatologic side effects have included postmarketing reports of rash.

Hematologic

Hematologic side effects have included postmarketing reports of thrombocytopenia.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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