Iloprost Side Effects

Not all side effects for iloprost may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to iloprost: inhalation solution

In addition to its needed effects, some unwanted effects may be caused by iloprost. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking iloprost:

Incidence not known
  • Black, tarry stools
  • chest pain
  • cough
  • difficult or labored breathing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • extreme fatigue
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • hives or rash
  • irregular breathing
  • itching
  • noisy breathing
  • pinpoint red spots on the skin
  • swelling of the eyelids, face, lips, fingers, feet, or lower legs
  • tightness in the chest
  • troubled breathing or swallowing
  • unusual bleeding or bruising

Some of the side effects that can occur with iloprost may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Back pain
  • chills
  • cough increased
  • coughing or spitting up blood
  • difficulty opening the mouth
  • feeling of warmth
  • headache
  • lockjaw
  • nausea
  • redness of the face, neck, arms, and occasionally, upper chest
  • sweating
  • trouble sleeping
Less common
  • Change in taste
  • mouth irritation
  • tongue irritation or pain
Incidence not known
  • Nosebleeds
  • stuffy nose

For Healthcare Professionals

Applies to iloprost: inhalation solution

Cardiovascular

Cardiovascular side effects have included congestive heart failure, chest pain, supraventricular tachycardia, peripheral edema, vasodilation (flushing), hypotension, palpitations and syncope.

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting. Postmarketing experience has included diarrhea.

Hepatic

Hepatic side effects have included increased GGT (gamma-glutamyltranspeptidase) and alkaline phosphatase levels.

Musculoskeletal

Musculoskeletal side effects have included muscle cramps, back pain, tongue pain and trismus.

Nervous system

Nervous system side effects have included headache, dizziness and insomnia.

Renal

Renal side effects have included kidney failure.

Respiratory

Respiratory side effects have included hemoptysis, pneumonia, dyspnea and increased cough. Postmarketing experience has included cases of bronchospasm and wheezing, particularly in susceptible patients with hyperreactive airways.

General

General side effects have included flu syndrome. Postmarketing reports have included mouth and tongue irritation and dysgeusia.

Other

Other side effects have included cases of epistaxis and gingival bleeding which have been reported within one month of starting iloprost treatment.

Hypersensitivity

Hypersensitivity side effects have included postmarketing reports of hypersensitivity and rash.

Dermatologic

Dermatologic side effects have included postmarketing reports of rash.

Hematologic

Hematologic side effects have included postmarketing reports of thrombocytopenia.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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